Results 11 to 20 of about 594,054 (108)
Journal of Diabetes, Volume 15, Issue 10, Page 866-880, October 2023., 2023 Highlights Nattokinase rescued endothelial dysfunction and pericyte loss in the diabetic retina. Nattokinase attenuated diabetes‐induced retinal inflammation and neurodegeneration. High mobility group box 1 signaling was involved in nattokinase‐mediated retinal protection.
Zijing Huang +11 more
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Veterinary Dermatology, Volume 34, Issue 5, Page 393-403, October 2023., 2023 Background – Grass leaf has been suspected to cause immunoglobulin (Ig)E‐mediated immediate hypersensitivity reactions both in humans and in dogs. However, most studies in this area are case control studies without in vitro data showing the involvement of IgE in the reaction.
Ken Mason, Janet Davies, Merja Ruutu
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The safety of rush immunotherapy in the management of canine atopic dermatitis—230 cases
Veterinary Dermatology, Volume 34, Issue 5, Page 385-392, October 2023., 2023 Background – The duration of the induction phase of allergen‐specific immunotherapy conventionally is a period of several weeks, during which the volume of an allergen solution, administered by injection, is gradually increased until the maintenance dose is reached.
Tamara Weitzer, Ralf Mueller
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电压依赖性阴离子通道1介导的炎症与睡眠呼吸暂停综合征 [PDF]
, 2023 线粒体电压依赖性阴离子通道1（VDAC1）是线粒体外膜上重要的通道蛋白，调控线粒体自噬，参与炎症因子的调节及炎症小体的激活，从而对炎症反应起着重要的作用。睡眠呼吸暂停综合征（OSAS）患者由于间歇性缺氧，氧化应激增加引起神经炎症，导致慢性损伤和神经元细胞凋亡，最终形成认知功能障碍。由于炎症在OSAS患者认知障碍的形成过程中起着重要的作用，而VDAC1调控着炎症小体的激活，因此本文综述了OSAS与炎症、OSAS与自噬之间的关系，并分析了VDAC1介导的炎症与线粒体自噬之间的相互作用 ...
刘纯飞, 徐平
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, 2018 目的:探讨除湿降气汤治疗反流性食管炎60例的临床效果。方法:选取2016年7月—2017年12月在我院就诊的反流性食管炎患者120例,根据随机数表法分为对照组和观察组,各60例。对照组采用常规西药治疗,观察组给予除湿降气汤治疗,比较两组治疗前、治疗8周时临床症状积分、食管黏膜炎症反应程度、疗效及不良反应情况。结果:观察组治疗8周时胃脘痛、胸骨后疼痛、烧心、反酸积分均较对照组低,差异有统计学意义 ...
赖畅钦
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, 2020 目的探讨甘露糖（Man）对炎症反应的调控及其机制，为甘露糖在炎症疾病中的应用提供依据。方法利用不同浓度的甘露糖处理RAW264.7巨噬细胞24 h或48 h，细胞计数检测增殖情况。低浓度（2 mmol/L）和高浓度（20 mmol/L）Man预处理RAW264.7细胞12 h，然后脂多糖（LPS）处理8 h或24 h，收集mRNA、蛋白质及培养上清，通过Q-PCR、Western blot和ELISA检测炎症相关指标以及甘露糖受体（CD206）的变化。结果在5 mmol/L以下 ...
胡因铭 +4 more
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Rare Metals, Volume 45, Issue 9, September 2026.ABSTRACT Ti‐15Mo‐2.5Ag alloy exhibited a low modulus and strong antibacterial ability but poor bioactivity. To resolve this problem, sandblasting and anodization were used to create a hydrophilic and nano‐Ag2O‐containing TiO2 coating. Subsequently, the microstructure and physicochemical properties were investigated by scanning electron microscopy, X ...
Yanchun Xie +11 more
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Rare Metals, Volume 45, Issue 7, July 2026.ABSTRACT Biodegradable zinc (Zn)‐based materials are considered promising candidates for orthopedic applications because of their favorable mechanical properties, controllable biodegradability, and good biosafety profiles. However, their clinical translation is limited by early‐stage corrosion‐induced cytotoxicity and inflammation, as well as ...
Jinlong Mao +9 more
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Rare Metals, Volume 45, Issue 7, July 2026.ABSTRACT The pathogenesis of diabetic foot ulcers is complex, often involving polymicrobial infection and persistent inflammatory responses, which lead to delayed or nonhealing wounds, posing a formidable clinical challenge. Existing photodynamic therapy reagents and traditional treatments generally address only a single pathological aspect, and the ...
Yu Zhang +16 more
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