Results 21 to 30 of about 14,134 (153)
Smart Biomaterials and Dressings for the Treatment of Chronic Inflammatory Skin Diseases
ABSTRACT Chronic inflammatory skin diseases, encompassing immune‐inflammatory conditions and infection‐associated dermatoses, pose significant clinical challenges due to high prevalence, recurrence, and therapeutic resistance, affect over 30% of the global population.
Zehao Lan +5 more
wiley +1 more source
Background: Normal hydration of the canine epidermis is imperative for cutaneous homeostasis. Xerosis may be encountered in canine atopic dermatitis and may be aggravated by topical antiseptics. Hypothesis and Objectives: To evaluate the hydrating properties and the safety of a spray (Sensiderm spray; MP Labo) when applied after shampooing healthy dogs
Adamantia Pseftogka +3 more
wiley +1 more source
ABSTRACT Objective To evaluate the use of twin vs singleton growth charts for detecting small‐for‐gestational‐age (SGA) twins at risk of adverse neonatal outcomes. Methods MEDLINE, EMBASE, CINAHL, Cochrane and Scopus databases were searched electronically from inception to May 2024.
S. Sorrenti +9 more
wiley +1 more source
The preliminary study on the dyslipidemia in rats with autoimmune myocarditis [PDF]
目的:心肌炎是心肌间质中局限或弥漫性的急性或慢性炎症,目前关于心肌炎中血脂代谢的相关研究较少,本课题通过建立大鼠实验性自身免疫性心肌炎模型(EAM模型),初步探讨心肌炎中血脂代谢紊乱可能的分子调节机制。 方法:利用猪心肌肌球蛋白和完全弗氏佐剂充分混合后,于第0天皮下注射建立大鼠EAM模型,留取心脏标本行组织切片H&E染色、心脏体重比、RealtimePCR、Westernblot评估心肌组织炎症程度;GPO-PAP法血脂试剂盒检测血脂水平;Filipin染色检测心肌组织内胆固醇水平 ...
戴东黎
core
Hydrocortisone Aceponate for Chronic Otitis: Long‐Term Efficacy
Effective management of otitis externa (OE) requires addressing all contributing factors to prevent chronicity and recurrence. Evidence on the long‐term efficacy of topical corticosteroids in preventing recurrence and secondary infections remains limited. This retrospective noncontrolled study evaluated the efficacy of hydrocortisone aceponate (HCA) in
C. Lorente‐Méndez, D. Alonso‐Miguel
wiley +1 more source
目的 探讨维持性血液透析(MHD)患者热休克蛋白70(HSP70)检测与炎症状态的关系。方法 将MHD患者92例根据超敏C反应蛋白(hs-CRP)水平分为2组:非炎症组(hs ...
刘琨
doaj
The relationship between the levels of white blood cell and lipopolysaccharide binding protein and intrahepatic triglyceride content , metabolic abnormalities in obese adults [PDF]
研究目的 非酒精性脂肪性肝病(NAFLD)常常伴随炎性因子的增多,且其发生发展与代谢综合征和胰岛素抵抗紧密相关。本研究针对中心性肥胖人群进行横断面数据分析,探讨白细胞(WBC)及脂多糖结合蛋白水平(LBP)与肝脏脂质含量(IHTC)及其相关代谢异常的关系。 研究方法 本研究纳入485名40-65岁中心性肥胖受试者,进行问卷调查包括病史、生活方式等;测定生化指标并进行胰岛功能评估;通过氢质子磁共振波谱(1H-MRS)技术定量分析肝内甘油三酯含量;进行内脏脂肪含量等测定 ...
孙倩
core
Background – Canine atopic dermatitis (cAD) is a chronic, inflammatory, multifactorial and pruritic disease. The presence of skin barrier impairment (e.g. filaggrin alterations), along with abnormal immune responses, can negatively impact cutaneous barrier function.
Wendie Roldan Villalobos +5 more
wiley +1 more source
微炎症是慢性肾脏病(CKD)患者在尿毒症毒素、补体、免疫复合物的刺激下,单核巨噬细胞系统被激活,促使血液中急性时相反应蛋白(CRP)、白介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)等炎性细胞因子升高,是一种长期低度非显性的炎症状态。慢性肾脏病早期即可出现微炎症状态,随着慢性肾脏病的进展呈加重趋势,是肾脏病众多并发症尤其是动脉粥样硬化的重要非传统致病因素。CRP、IL-6、TNF-α是最能反应微炎症状态的指标。
杨爽 +4 more
doaj
The effect and mechanism of IL-1 R II / IL-1 RAcp in Autoimmune Myocarditis [PDF]
【目的】白介素-1(IL-1)是一种T淋巴细胞激活因子,大量研究报道,在心肌炎急性期表达量明显升高。白介素1受体II型(IL-1RII)可以招募白介素1受体辅助蛋白(IL-1RAcp),从而拮抗IL-1β的作用。本课题目的为评估IL-1RII和IL-1RAcp的重组质粒对大鼠自身免疫性心肌炎(EAM)的作用,并进一步探讨其机制,为心肌炎的临床治疗提供理论基础。 【方法】首先在临床实验中,我们选取厦门市心血管病医院诊断明确的心肌炎住院患者28例,应用bio ...
宋颖
core

