Results 21 to 30 of about 594,054 (108)
ABSTRACT Managing diabetic wounds requires simultaneously addressing their infectious, oxidative, and regenerative impairments. To address this, this study integrates a piezoelectric BiOCl@CuSe heterojunction (PFM‐verified) into an injectable F127/HA hydrogel, creating an ultrasound‐responsive smart dressing.
Jiayan Guo +5 more
wiley +1 more source
Biodegradable Mg Alloys: Enhancing Anti‐tumor Immunity in Cancer Therapy
ABSTRACT Magnesium (Mg) alloys, as biodegradable metallic materials with excellent biocompatibility and mechanical properties, demonstrate significant advantages. In the field of immunotherapy, they present a promising potential option for enhancing therapeutic outcomes and hold broad prospects for application.
Can Feng +8 more
wiley +1 more source
Use of a Cytobrush for Sampling the Ear Canal of Dogs With Otitis Externa
Cytological examination of the ear canal is essential for evaluating dogs with otitis externa (OE). The conventional sampling method uses a swab. However, the cytobrush (gynaecological cervical brush), already used for cytological collection from other anatomical sites, has not been adequately investigated for this purpose in dogs with OE.
Nicoly Radaeli Atanasio +3 more
wiley +1 more source
ABSTRACT Skin wound injuries are often accompanied by bacterial infections and severe inflammation. Especially, M1‐type macrophages at the wound site can trigger a cascade of inflammatory responses, mediating a vicious cycle of inflammation. Meanwhile, hypoxia further exacerbates vascular damage and constriction in the wound microenvironment, thereby ...
Xianfeng Wang +6 more
wiley +1 more source
Smart Biomaterials and Dressings for the Treatment of Chronic Inflammatory Skin Diseases
ABSTRACT Chronic inflammatory skin diseases, encompassing immune‐inflammatory conditions and infection‐associated dermatoses, pose significant clinical challenges due to high prevalence, recurrence, and therapeutic resistance, affect over 30% of the global population.
Zehao Lan +5 more
wiley +1 more source
目的:从炎症反应相关信号探讨焦虑症肝郁化火的形成机制。方法:采用单笼饲养和不确定性空瓶饮水应激建立肝郁化火焦虑模型。Wistar大鼠随机分成空白对照组、模型组,在应激第7天和14天用高架十字迷宫试验、旷场实验及明暗箱实验行为学评价,ELISA法测定外周血清和杏仁核中炎症因子IL-1β、IL-6、TNF-α、IL-10含量及mRNA表达水平。结果:模型组肝郁化火时(应激第14天)血清和杏仁核IL-1β、IL-6、TNF-α含量均显著增加 ...
邓潇斐 +7 more
core
Background: Normal hydration of the canine epidermis is imperative for cutaneous homeostasis. Xerosis may be encountered in canine atopic dermatitis and may be aggravated by topical antiseptics. Hypothesis and Objectives: To evaluate the hydrating properties and the safety of a spray (Sensiderm spray; MP Labo) when applied after shampooing healthy dogs
Adamantia Pseftogka +3 more
wiley +1 more source
ABSTRACT Objective To evaluate the use of twin vs singleton growth charts for detecting small‐for‐gestational‐age (SGA) twins at risk of adverse neonatal outcomes. Methods MEDLINE, EMBASE, CINAHL, Cochrane and Scopus databases were searched electronically from inception to May 2024.
S. Sorrenti +9 more
wiley +1 more source
表皮生长因子受体抑制剂对外源锌离子致大鼠急性呼吸道炎症的影响 [PDF]
目的:探讨表皮生长因子受体(EGFR)抑制剂对外源锌离子致大鼠呼吸道急性炎症的影响。方法:将100μmol/L硫酸锌溶液经气管灌注大鼠肺部复制动物炎症模型,于灌注后4h、8h和24h处死大鼠,以PBS为对照,分别测定支气管肺泡灌洗液(BALF)中白细胞计数、总蛋白、白细胞介素8(IL-8)以及乳酸脱氢酶(LDH)的含量,以选择炎症最明显的时间点。进一步用二甲基亚砜(DMSO)和EGFR抑制剂PD153035预灌注大鼠,观察其对硫酸锌溶液所致呼吸道炎症的影响。结果:不同灌注液作用后大鼠白细胞计数(F=12.
关文池 +7 more
core
Hydrocortisone Aceponate for Chronic Otitis: Long‐Term Efficacy
Effective management of otitis externa (OE) requires addressing all contributing factors to prevent chronicity and recurrence. Evidence on the long‐term efficacy of topical corticosteroids in preventing recurrence and secondary infections remains limited. This retrospective noncontrolled study evaluated the efficacy of hydrocortisone aceponate (HCA) in
C. Lorente‐Méndez, D. Alonso‐Miguel
wiley +1 more source

