Results 11 to 20 of about 194,577 (104)
免疫抑制宿主肺炎与淋巴细胞的相关性及激素对重症患者结局的影响
Zhongshan Daxue xuebao. Yixue kexue ban, 2022 目的探究免疫抑制宿主肺炎患者外周血中淋巴细胞与疾病严重程度的相关性，和不同剂量激素使用方案对重症患者临床结局的影响。方法收集免疫抑制宿主肺炎患者的临床资料，根据ATS/IDSA指南重症肺炎标准，将患者分为重症组和非重症组。采用logistic回归分析筛出与免疫抑制宿主肺炎患者发展为重症肺炎相关的危险因素，并绘制受试者工作曲线（ROC）以评估各危险因素对重症免疫抑制宿主肺炎的预测价值。同时，根据重症组的激素使用情况，将重症患者分为重症+高剂量激素组（泼尼松龙用量≥1 mg·kg-1·d-1或等效剂量激素）、
吴燕茹, 曾勉
doaj
Rare Metals, Volume 45, Issue 9, September 2026.ABSTRACT Cisplatin‐related acute kidney injury (CP‐AKI) is a serious complication of cisplatin (CP) treated patients with cancer with high morbidity and mortality rates. It is directly related to the abnormal accumulation of CP in renal tubular epithelial cells, causing metabolic toxicity, DNA damage, and oxidative stress.
Minghe Jiang +12 more
wiley +1 more source
Rare Metals, Volume 45, Issue 9, September 2026.ABSTRACT Ti‐15Mo‐2.5Ag alloy exhibited a low modulus and strong antibacterial ability but poor bioactivity. To resolve this problem, sandblasting and anodization were used to create a hydrophilic and nano‐Ag2O‐containing TiO2 coating. Subsequently, the microstructure and physicochemical properties were investigated by scanning electron microscopy, X ...
Yanchun Xie +11 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2021 葡萄膜炎是一类世界范围内的眼科疾病,又称为色素膜炎,是虹膜、睫状体、脉络膜炎症的总称,因其发病机制复杂,引起的并发症和后遗症有致盲的风险,目前备受医学领域的关注[1-2]。葡萄膜炎与强直性脊柱炎(AS)作为免疫性疾病,关系密切。葡萄膜炎是AS的最常见的关节外表现,发病率约占10%-40%[3-4]。葡萄膜炎也可作为AS的首发症状出现[5]。AS是一种起病隐匿的慢性疾病,
杜连泽 +4 more
doaj
Rare Metals, Volume 45, Issue 7, July 2026.ABSTRACT Biodegradable zinc (Zn)‐based materials are considered promising candidates for orthopedic applications because of their favorable mechanical properties, controllable biodegradability, and good biosafety profiles. However, their clinical translation is limited by early‐stage corrosion‐induced cytotoxicity and inflammation, as well as ...
Jinlong Mao +9 more
wiley +1 more source
Rare Metals, Volume 45, Issue 7, July 2026.ABSTRACT Deep skin infections and dense biofilm barriers caused by Propionibacterium acnes (P. acnes) remain significant challenges in recurrent acne vulgaris, exacerbated by the poor stratum corneum penetration of conventional therapies and rising antibiotic resistance.
Bingran Qi +3 more
wiley +1 more source
間質性肺炎合併自己免疫性炎症性筋疾患におけるADAM-17の検討 [PDF]
, 2018 A disintegrin and metalloprotease （ADAM） familyは組織障害や炎症反応において重要な役割を担っていると考えられている．ADAM-17はtumor necrosis factor （TNF）-αをsheddingする蛋白分解酵素として最初に発見された．今回，われわれは，自己免疫性炎症性筋疾患におけるADAM-17の発現と間質性肺炎での炎症における役割を検討した．自己免疫性炎症性筋疾患（多発性筋炎26名，皮膚筋炎34名，clinically amyopathic ...
西見, 愛里 +2 more
core +2 more sources
Rare Metals, Volume 45, Issue 7, July 2026.ABSTRACT Bone defect repair in elderly patients is frequently compromised by reduced osteogenic capacity and delayed healing. Chronic inflammation‐driven inflammaging is a critical contributor to this impairment, characterized by dysfunctional autophagy in senescent macrophages (S‐MΦs), excessive reactive oxygen species (ROS) accumulation, and ...
Ruiyue Hang +6 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2015 肺炎是指由不同病原体或其他（如吸入、过敏反应）因素等所引起的肺部炎症反应。按病情轻、重程度不同分为轻症肺炎和重症肺炎。轻症肺炎以呼吸系统受累为主要表现,呼吸系统外的其他系统仅轻度受累,且不伴有全身中毒症状;重症肺炎除重度呼吸系统症状外,循环系统、神经系统、消化系统等其他系统也严重受累。支气管肺炎常合并的多脏器损害最常见的是心脏损害 ...
陈彦伶, 盛岩
doaj
Rare Metals, Volume 45, Issue 7, July 2026.ABSTRACT The pathogenesis of diabetic foot ulcers is complex, often involving polymicrobial infection and persistent inflammatory responses, which lead to delayed or nonhealing wounds, posing a formidable clinical challenge. Existing photodynamic therapy reagents and traditional treatments generally address only a single pathological aspect, and the ...
Yu Zhang +16 more
wiley +1 more source