Results 11 to 20 of about 161,714 (162)
炎症小体是一类多蛋白复合物,主要由识别炎症的胞浆型模式识别受体、衍接蛋白和效应蛋白三部分组成。 炎症小体组装激活可以自我切割生成活性形式的caspase-1,并进一步促进白细胞介素-1β(IL-1β)和白细胞介素-18(IL- 18)等炎症因子的成熟和释放,引起炎症反应。此外炎症小体激活可介导caspase-1依赖的细胞焦亡,从而促进炎症反应的 扩散。炎症小体根据识别信号的模式识别受体命名,其中NLRP3炎症小体是目前研究最多了解相对最清楚的炎症小体 ...
谭红梅
doaj +1 more source
肺炎球菌性肺炎の成立機序として,呼吸器ウイルスの先行感染による気道上皮細胞への菌付着の重要性が示唆される.本邦の114症例の成人における肺炎球菌 性肺炎症例の臨床像と起炎菌の薬剤耐性を検討した.患者の平均年齢は67.4歳で,菌血症頻度(2.6%),致命率(4.4%)は欧米の成績に比較して低 率であった.起炎菌のペニシリンおよびマクロライド耐性は高いものの ...
吉嶺, 裕之, 大石, 和徳
core +2 more sources
oai:jichi-ir.repo.nii.ac.jp:000000102000年からの10年間で経験した当科における劇症肝炎28例について臨床的に検討し,2007年全国調査集計結果と比較検討を行った。平均年齢は53(26~73)歳。男女比は15:13。急性型,亜急性型の比は14:14であった。成因としてはB型肝炎ウィルスが17例(60%)で最も多かった。全例で血漿交換を行い,肝庇護療法としてはステロイドパルス療法が21例(75%)に行われた。生体肝移植は2例(7.1%)行われた。28例中12例(42 ...
佐藤, 慎 +9 more
core
ABSTRACT Managing diabetic wounds requires simultaneously addressing their infectious, oxidative, and regenerative impairments. To address this, this study integrates a piezoelectric BiOCl@CuSe heterojunction (PFM‐verified) into an injectable F127/HA hydrogel, creating an ultrasound‐responsive smart dressing.
Jiayan Guo +5 more
wiley +1 more source
ABSTRACT Diabetic wound infections are a common complication of diabetes, which severely impact patients' quality of life. Effective treatment of diabetic wound infections remains one major challenge in the clinic, partially due to the formation of bacterial biofilm and antibiotic resistance.
Liang Zhou +8 more
wiley +1 more source
炎症和免疫是脑血管病病理生理的重要部分,其动态变化影响着脑血管病的进程和预后。缺血性卒中急性期的炎症激活造成大脑病灶的炎症损伤,还参与衰老相关的脑小血管病的脑损害,引起血管性痴呆等认知功能障碍。本文就炎症和免疫与脑血管病相互作用机制的研究进展进行综述 ...
陆正齐
core
肺炎是指由不同病原体或其他(如吸入、过敏反应)因素等所引起的肺部炎症反应。按病情轻、重程度不同分为轻症肺炎和重症肺炎。轻症肺炎以呼吸系统受累为主要表现,呼吸系统外的其他系统仅轻度受累,且不伴有全身中毒症状;重症肺炎除重度呼吸系统症状外,循环系统、神经系统、消化系统等其他系统也严重受累。支气管肺炎常合并的多脏器损害最常见的是心脏损害 ...
陈彦伶, 盛岩
doaj
Biodegradable Mg Alloys: Enhancing Anti‐tumor Immunity in Cancer Therapy
ABSTRACT Magnesium (Mg) alloys, as biodegradable metallic materials with excellent biocompatibility and mechanical properties, demonstrate significant advantages. In the field of immunotherapy, they present a promising potential option for enhancing therapeutic outcomes and hold broad prospects for application.
Can Feng +8 more
wiley +1 more source
Use of a Cytobrush for Sampling the Ear Canal of Dogs With Otitis Externa
Cytological examination of the ear canal is essential for evaluating dogs with otitis externa (OE). The conventional sampling method uses a swab. However, the cytobrush (gynaecological cervical brush), already used for cytological collection from other anatomical sites, has not been adequately investigated for this purpose in dogs with OE.
Nicoly Radaeli Atanasio +3 more
wiley +1 more source

