Results 21 to 30 of about 161,714 (162)
血清IL-6、TNF-α、IL-10的动态监测在儿童重症肺炎中临床意义
Zhongguo shiyan zhenduanxue, 2015 肺炎是儿童的常见疾病,其中有7%-13%是重症肺炎[1],与其他炎症一样,肺炎本是一种局部的感染炎症。若感染未得到控制,肺部受累面积较大,不仅导致低氧血症及高碳酸血症,同时病原微生物侵入气道后,支气管及肺泡巨噬细胞吞噬、杀灭病原体并对病原体加工处理,将抗原信息提呈给T淋巴细胞,同时释放大量细胞因子（cytokine,CK）等参与炎症反应,促炎与抑炎反应的平衡 ...
黄光举 +4 more
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Rare Metals, Volume 45, Issue 3, March 2026.ABSTRACT Skin wound injuries are often accompanied by bacterial infections and severe inflammation. Especially, M1‐type macrophages at the wound site can trigger a cascade of inflammatory responses, mediating a vicious cycle of inflammation. Meanwhile, hypoxia further exacerbates vascular damage and constriction in the wound microenvironment, thereby ...
Xianfeng Wang +6 more
wiley +1 more source
Rare Metals, Volume 45, Issue 3, March 2026.ABSTRACT Periodontitis is a chronic infectious oral disease triggered by periodontopathogenic bacteria, resulting in the progressive inflammation and destruction of the tissues surrounding teeth. To achieve reprogramming of the infectious microenvironment for periodontitis therapy, a nanoformulation was proposed by loading polydopamine (PDA) with ...
Hao Liang +14 more
wiley +1 more source
犬の炎症性腸疾患における炎症性サイトカイン発現解析に関する研究 [PDF]
, 2014 犬の炎症性腸疾患（IBD）は慢性の消化器症状を示す原因不明で難治性の疾患群である。小腸性に起こるリンパ球形質細胞性腸炎（LPE）と大腸性に起こるリンパ球形質細胞性結腸炎（LPC）が最も一般的な病型である。LPEとLPCの診断は、除外診断により他の疾患を除外し、病変部の病理組織検査によりリンパ球と形質細胞の浸潤が粘膜に認められたものとされる。一方で、炎症性結直腸ポリープ（ICRPs）は近年国内のミニチュア・ダックスフンドで主に認識されてきている結直腸の炎症性疾患である ...
田村, 悠
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Zhongguo shiyan zhenduanxue, 2015 目的通过检测急性肺炎患者的P-选择素和血小板参数水平预测患者的病情及预后,为临床治疗提供参考。方法选取2010年3月—2013年3月我院收治的117例肺炎患者,按照病情程度分为轻症肺炎组和重症肺炎组,随机选取在我院体检中心体检的健康体检者120例为对照组,检测并比较三组对象的P-选择素水平和血小板参数。结果三组对象血浆P-选择素比较,差异有统计学意义 ...
严宇鹏 +5 more
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Multi‐Functional S‐HA/ASTA NPs Coating on Biodegradable ZE21B Alloy for Cerebrovascular Applications
Rare Metals, Volume 45, Issue 2, February 2026.ABSTRACT Magnesium (Mg) and its alloys have attracted extensive attention of researchers in the field of cerebrovascular implants due to their good mechanical properties and biosafety. However, rapid degradation and delayed endothelialization pose challenges. To address these issues, this study introduces a multifunctional composite coating.
Aqeela Yasin +4 more
wiley +1 more source
Smart Biomaterials and Dressings for the Treatment of Chronic Inflammatory Skin Diseases
Rare Metals, Volume 45, Issue 2, February 2026.ABSTRACT Chronic inflammatory skin diseases, encompassing immune‐inflammatory conditions and infection‐associated dermatoses, pose significant clinical challenges due to high prevalence, recurrence, and therapeutic resistance, affect over 30% of the global population.
Zehao Lan +5 more
wiley +1 more source
慢性房颤患者心房组织中SOCS-1和IL-23水平的动态变化与房颤的关系
Zhongguo shiyan zhenduanxue, 2017 近年来,有关炎症与炎症因子在房颤（AF）发病过程中的作用越来越引起人们重视。白细胞介素-23（IL-23）主要是由活化的单核巨噬细胞及树突状细胞分泌的炎症细胞因子,与许多炎症疾病有关,有学者发现它参与了AF的病理过程[1]。细胞因子信号转导负调控因子-1（SOCS-1）是由炎症因子激活JAK/STAT通路产生的一种炎症因子,它反过来通过抑制该通路对炎症反应有负调控作用,本文对慢性AF患者心房组织中SOCS-1和IL ...
王朋 +5 more
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Advances in Elemene Nanodelivery Systems: From Material Design to Disease Treatment
Rare Metals, Volume 45, Issue 2, February 2026.ABSTRACT Elemene (ELE) is a bioactive sesquiterpenoid extracted from traditional Chinese herbs, demonstrating broad‐spectrum antitumor, anti‐inflammatory, and analgesic properties with significant therapeutic potential. However, its clinical utility is constrained by inherent physicochemical limitations, including volatility and hydrophobicity, which ...
Xiao Wang +9 more
wiley +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2022 慢性鼻窦炎（CRS）是一种高异质性疾病，不同种族和地域的CRS患者表现为不同的流行病学和内在型特征。尽管经历了充分和规律的药物和手术治疗，仍有相当比例的CRS患者治疗后复发。复发性、难治性CRS为CRS的临床治疗提出了严峻挑战。2型生物制剂的问世，为难治性、复发性CRS的治疗带来了曙光。近年来，靶向2型炎症的生物制剂在治疗西方国家患者的难治性CRS方面表现出了令人鼓舞的治疗效果。但是由于炎症特征存在异质性，西方CRS患者以嗜酸粒细胞性2型炎症为主，而亚洲CRS患者更多地表现为1型炎症 ...
白瑜蓉, 张雅娜
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