Results 21 to 30 of about 51,189 (166)
Multi‐Functional S‐HA/ASTA NPs Coating on Biodegradable ZE21B Alloy for Cerebrovascular Applications
Rare Metals, Volume 45, Issue 2, February 2026.ABSTRACT Magnesium (Mg) and its alloys have attracted extensive attention of researchers in the field of cerebrovascular implants due to their good mechanical properties and biosafety. However, rapid degradation and delayed endothelialization pose challenges. To address these issues, this study introduces a multifunctional composite coating.
Aqeela Yasin +4 more
wiley +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2017 炎症小体是一类多蛋白复合物，主要由识别炎症的胞浆型模式识别受体、衍接蛋白和效应蛋白三部分组成。 炎症小体组装激活可以自我切割生成活性形式的caspase-1，并进一步促进白细胞介素-1β（IL-1β）和白细胞介素-18（IL- 18）等炎症因子的成熟和释放，引起炎症反应。此外炎症小体激活可介导caspase-1依赖的细胞焦亡，从而促进炎症反应的 扩散。炎症小体根据识别信号的模式识别受体命名，其中NLRP3炎症小体是目前研究最多了解相对最清楚的炎症小体 ...
谭红梅
doaj
Mindin is up-regulated during colitis and enhances inflammation by activating the transcription activity of NF-κB protein family [PDF]
, 2015 炎症性肠病（IBD）的发生，被认为是遗传、环境和黏膜免疫三方面因素共同作用的结果,而肠黏膜异常的免疫应答又是发病的关键因素之一。在炎症局部，炎性细胞的招募和激活依赖各种细胞膜受体及整合素与细胞基质（ECM）间的相互作用。细胞外基质蛋白Mindin是Mindin/F-spondin家族成员，在小鼠炎症模型中，有多项研究表明Mindin在免疫应答过程中扮演重要角色，但对于其在炎症中的功能和调控机制研究较少。故本课题拟探索肠炎中Mindin的表达水平及其在炎症中的信号调控机制。 本课题研究中 ...
李萍
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Smart Biomaterials and Dressings for the Treatment of Chronic Inflammatory Skin Diseases
Rare Metals, Volume 45, Issue 2, February 2026.ABSTRACT Chronic inflammatory skin diseases, encompassing immune‐inflammatory conditions and infection‐associated dermatoses, pose significant clinical challenges due to high prevalence, recurrence, and therapeutic resistance, affect over 30% of the global population.
Zehao Lan +5 more
wiley +1 more source
血清IL-6、TNF-α、IL-10的动态监测在儿童重症肺炎中临床意义
Zhongguo shiyan zhenduanxue, 2015 肺炎是儿童的常见疾病,其中有7%-13%是重症肺炎[1],与其他炎症一样,肺炎本是一种局部的感染炎症。若感染未得到控制,肺部受累面积较大,不仅导致低氧血症及高碳酸血症,同时病原微生物侵入气道后,支气管及肺泡巨噬细胞吞噬、杀灭病原体并对病原体加工处理,将抗原信息提呈给T淋巴细胞,同时释放大量细胞因子（cytokine,CK）等参与炎症反应,促炎与抑炎反应的平衡 ...
黄光举 +4 more
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MK2 inhibitor selectively reduces alkali burn-induced inflammation and neovascularization in cornea [PDF]
, 2016 眼化学烧伤是一类常见的眼外伤疾病，特别是在发展中国家。与酸性烧伤相比，碱性烧伤更为常见。碱性物质可快速穿透眼前房，导致慢性炎症和角膜浑浊，从而导致严重且持久的视觉缺损。尽管角膜移植手术是一项有效的治疗方法，然而其成功与否取决于角膜的炎症和新生血管是否得到控制。尽管目前有许多用于治疗角膜炎症和新生血管的药物，然而由于其有一定的副作用或仅仅通过缓解症状而非从根本途径进行治疗，因此亟须从发病机制入手寻找新的治疗办法。 持久的角膜炎症与新生血管，不仅会导致永久的视觉缺失，还会使行角膜手术的时机推迟 ...
陈艳丰
core
Advances in Elemene Nanodelivery Systems: From Material Design to Disease Treatment
Rare Metals, Volume 45, Issue 2, February 2026.ABSTRACT Elemene (ELE) is a bioactive sesquiterpenoid extracted from traditional Chinese herbs, demonstrating broad‐spectrum antitumor, anti‐inflammatory, and analgesic properties with significant therapeutic potential. However, its clinical utility is constrained by inherent physicochemical limitations, including volatility and hydrophobicity, which ...
Xiao Wang +9 more
wiley +1 more source
血小板は、2型自然リンパ球と複合体を形成することで2型自然リンパ球の活性を高める [PDF]
, 2019 博士(医学) 甲第713号(主論文の要旨、要約、審査結果の要旨)博士(医学 ...
折茂 圭介
core +1 more source
Veterinary Dermatology, Volume 37, Issue 1, Page 140-147, February 2026.Background: Normal hydration of the canine epidermis is imperative for cutaneous homeostasis. Xerosis may be encountered in canine atopic dermatitis and may be aggravated by topical antiseptics. Hypothesis and Objectives: To evaluate the hydrating properties and the safety of a spray (Sensiderm spray; MP Labo) when applied after shampooing healthy dogs
Adamantia Pseftogka +3 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2015 目的通过检测急性肺炎患者的P-选择素和血小板参数水平预测患者的病情及预后,为临床治疗提供参考。方法选取2010年3月—2013年3月我院收治的117例肺炎患者,按照病情程度分为轻症肺炎组和重症肺炎组,随机选取在我院体检中心体检的健康体检者120例为对照组,检测并比较三组对象的P-选择素水平和血小板参数。结果三组对象血浆P-选择素比较,差异有统计学意义 ...
严宇鹏 +5 more
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