血清PSA、GDF3与MUC1蛋白的联合检测在早期乳腺癌患者中的诊断意义
人生长分化因子3(GDF3)与早期胚胎发育及脂肪生成关系密切,是转化生子因子-β(TGF-β)的一个主要组成成员,对乳腺癌(BC)的发生发展具有一定的促进作用[1]。血清前列腺特异抗原(PSA)在正常及癌样上皮细胞内均可合成,属于丝氨酸蛋白酶家族成员之一,具有组织特异性,起糜蛋白酶样作用[2]。黏蛋白1(MUC1 ...
常庆龙, 杨红星
doaj
【目的】探讨腺病毒介导的大肠杆菌胞嘧啶脱氨酶(E .coli CD)基因在胰腺癌细胞中靶向性表达的可能性及其作 用。【方法】将含癌胚抗原(carcinoembryonic antigen CEA)启动子的重组腺病毒感染人胰腺癌SW1990 细胞(CEA+)、Capan-2 细 胞(CEA-)和人宫颈癌Hela 细胞, 观察CD 基因在3 种细胞中的表达及细胞对5-FC 的敏感性差异。【结果】腺病毒介导CD 基 因仅在SW1990 细胞中呈专一性表达, 转导CD 基因的SW1990 细胞对5-FC ...
张世能, 袁世珍
doaj
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