Results 11 to 20 of about 14,071 (155)
Journal of Diabetes, Volume 15, Issue 7, Page 545-556, July 2023., 2023 Highlights High stress hyperglycemia ratio (SHR) was associated with elevated systematic inflammation in diabetic inpatients with pneumonia on admission. In the absence of hypoglycemia on admission, SHR was of J‐shaped associations with adverse clinical outcomes in diabetic inpatients with pneumonia of different severity.
Bing Liu, Yu Chen, Liping Yu, Min Zhou
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Journal of Diabetes, Volume 15, Issue 6, Page 519-531, June 2023., 2023 Highlights For distinguishing glucokinase maturity‐onset diabetes of the young (GCK‐MODY) from hepatocyte nuclear factor 1‐α MODY (HNF1A‐MODY), total triglycerides may help during the follow‐up period. In order to discriminate GCK‐MODY from MODY‐like type 2 diabetes, high‐sensitivity C‐reactive protein may be a suitable indicator in the early stage ...
Jing Liu +3 more
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Journal of Diabetes, Volume 15, Issue 5, Page 436-447, May 2023., 2023 Highlights To our knowledge, our study is the first to date to investigate the association between metabolically defined obesity and adverse outcomes in patients with chronic myeloid leukemia (CML). Metabolic abnormalities were associated with adverse outcomes in patients with CML, irrespective of obesity status.
Yingchun Dong +11 more
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Journal of Diabetes, Volume 15, Issue 1, Page 7-14, January 2023., 2023 Highlights Red blood cell (RBC) lifespan variation, is the main cause of variation in glycosylated hemoglobin (HbA1c), independent of blood glucose levels. This study highlighted the important impact of RBC lifespan on HbA1c test value in T2DM with HbA1c test value <7%. We discovered that the HbA1c test value in type 2 diabetes (T2DM) patients with RBC
Junmei Wang +6 more
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Veterinary Dermatology, Volume 33, Issue 4, Page 329-e77, August 2022., 2022 Background– Cannabidiol (CBD) and cannabidiolic acid (CBDA) are reported to have antinociceptive, immunomodulatory and anti‐inflammatory actions. Objectives – To determine if CBD/CBDA is an effective therapy for canine atopic dermatitis (cAD). Conclusions and clinical relevance – Cannabidiol/CBDA as an adjunct therapy decreased pruritus, and not skin ...
Melissa Loewinger +4 more
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Onset and duration of action of lokivetmab in a canine model of IL‐31 induced pruritus
Veterinary Dermatology, Volume 32, Issue 6, Page 681-e182, December 2021., 2021 Onset of antipruritic action of lokivetmab in dogs. Laboratory‐bred beagle dogs were dosed subcutaneously with either placebo or lokivetmab at 2.0 mg/kg on Day (D) 0. Approximately 2.5 h post‐dosing, pruritus was induced using canine interleukin (IL)‐31. Animals were observed for pruritic behaviours for a total of 2 h (3–5 h post‐treatment with placebo
Timothy J. Fleck +6 more
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Effects of Non-invasive Positive Pressure Ventilation on Sleep of Patients in Respiratory Intensive Care Unit Assessed by Overnight Polysomnography [PDF]
, 2022 BackgroundSleep disorders are commonin RICU patients, with mechanical ventilation as one of the important factors leading to sleep disorders in RICU patients.
LIU Yanan, WANG Xi, ZHANG Cheng, SHEN Yane, MA Jing, WANG Guangfa
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Developmental Medicine &Child Neurology, Volume 61, Issue 3, Page E1-E35, March 2019., 2019 目的 本国际临床指南由欧洲残疾儿童学会（the European Academy of Childhood Disability，EACD）牵头制定，旨在解决发育性协调障碍（developmental coordination disorder，DCD）的定义、诊断、评估、干预以及与社会心理方面的临床应用关键问题。 方法 本指南针对五个领域的关键问题，通过文献综述和专家团队的正式讨论达成共识。为保证指南的循证基础，以“机制”、“评估”和“干预”为检索词, 对2012年更新以来提出的最新建议以及新增的“社会心理问题”和“青少年/成人”为检索词进行检索。根据牛津大学循证医学中心证据等级 (证据水平 [level of evidence, LOE]1–4) 将结果进行分类，最终转化为指南建议。并由国际 ...
Jing Hua +6 more
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Effects of Polybrominated Diphenyl Ethers on the Human Body Exposure in E-Waste Dismantling Region [PDF]
, 2020 Objective To discuss the effects of polybrominated diphenyl ethers （PBDEs） exposure in e-waste dismantling region on the human body and provide data support for the identification of environmental health damage to residents in the e-waste dismantling ...
ZHOU Yan, Lü Shao-min, XIAO Jian-peng, et al
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Zhongguo shiyan zhenduanxue, 2023 目的 探讨结直肠癌组织和细胞中人整合素α6的表达特点及作用。方法 以人结直肠癌细胞株HT-29、RKO,人永生化结肠上皮细胞系IMCE,以及结直肠癌组织和癌旁正常组织为研究对象。Western blot检测整合素α6在结直肠癌组织和癌细胞中的表达特点；使用整合素α6慢病毒过表达载体转染结直肠癌细胞，进行Transwell细胞迁移和侵袭实验；同时检测整合素α6过表达对结直肠癌细胞E-钙黏蛋白、N-钙黏蛋白、波形蛋白、p-Smad2及Smad2蛋白表达水平。结果 结直肠癌HT-29细胞 ...
邢艳丽 +4 more
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