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肾移植受者外周血白细胞CMV 抗原阳性细胞数及意义 [PDF]

Zhongshan Daxue xuebao. Yixue kexue ban, 2001
【目的】探讨肾移植受者外周血白细胞巨细胞病毒(CMV)PP-65 抗原阳性细胞数的变化及意义。【方法】用免疫 细胞化学法检测外周血白细胞CMV-PP65 抗原, 术后头3 个月每周1 次。【结果】273 例肾移植受者中124 例术后检出CMVPP65 抗原阳性, 初次检出CM V-PP65 抗原的平均时间为(24.1±11.3)d, 每5 万白细胞中CMV 抗原阳性细胞数均值为7.1 ±5.8 , 其中5 例CMV 抗原阳性细胞数超过10/ 5 万白细胞。无症状性和症状性CMV ...
许元文, 毛海萍, 梁艳冰
doaj   +1 more source

SARS‐CoV‐2 infection as cause of in‐utero fetal death: regional multicenter cohort study

Ultrasound in Obstetrics &Gynecology, Volume 62, Issue 6, Page 867-874, December 2023., 2023
ABSTRACT Objective Placental infection with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) can lead to placental insufficiency and in‐utero fetal death (IUFD). The objective of this study was to confirm and quantify the extent to which fetoplacental infection with SARS‐CoV‐2 is a cause of fetal death.
M. Nkobetchou, M. Leruez‐Ville, T. Guilleminot, N. Roux, G. Petrilli, F. Guimiot, M.‐H. Saint‐Frison, I. Deryabin, Y. Ville, V. Faure‐Bardon   +9 more
wiley   +1 more source

Associations of per‐ and polyfluoroalkyl substance concentrations in the blood of Amur tigers and physiological parameters 东北虎血液中全氟和多氟烷基化合物浓度与生理参数的关系

Wildlife Letters, Volume 1, Issue 4, Page 163-170, December 2023., 2023
Per‐ and polyfluoroalkyl substances (PFASs), especially long‐chain perfluorinated carboxylates and perfluorinated sulfonic acids, were considered as global environmental contaminants due to their wide industrial and commercial applications and their threat to human and animal health.
Luyao Wang, Dan You, Haitao Xu, Wei Xie, Mengna Chen, Qinjie Chang, Hongyu Jiang, Yajun Wang   +7 more
wiley   +1 more source

Decreased in n‐3 DHA enriched triacylglycerol in small extracellular vesicles of diabetic patients with cardiac dysfunction 糖尿病合并心脏功能障碍患者细胞外小囊泡中n‐3 DHA 富集的三酰甘油减少

Journal of Diabetes, Volume 15, Issue 12, Page 1070-1080, December 2023., 2023
Highlights Lipid profiles of small extracellular vesicles (sEVs) in patients with diabetes or diabetic cardiovascular disease are rarely reported. n‐3 docosahexaenoic acid (DHA)‐enriched triacylglycerol (TG) was found to decrease in sEVs from serum of patients with diabetic cardiovascular disease (DM‐CAD).
Wei Ding, Xuejuan Zhang, Dandan Xiao, Wenguang Chang   +3 more
wiley   +1 more source

Fatty acid β‐oxidation and mitochondrial fusion are involved in cardiac microvascular endothelial cell protection induced by glucagon receptor antagonism in diabetic mice 脂肪酸β‐氧化和线粒体融合参与胰高血糖素受体拮抗剂对糖尿病小鼠心脏微血管内皮细胞的保护作用

Journal of Diabetes, Volume 15, Issue 12, Page 1081-1094, December 2023., 2023
Highlights Glucagon receptor (GCGR) monoclonal antibody (mAb) improves cardiac function and attenuates microvascular damage in db/db mice. GCGR mAb ameliorates the oxidative stress of cardiac microvascular endothelial cells in diabetic mice. GCGR mAb counteracts the diabetes‐induced upregulation of carnitine palmitoyltransferase 1B, optic atrophy type ...
Peng Wang, Rui Wei, Xiaona Cui, Zongzhe Jiang, Jin Yang, Lingyun Zu, Tianpei Hong   +6 more
wiley   +1 more source

Correlation analysis of IL‐37 gene polymorphisms and susceptibility to chronic HBV infection among Han people in Central China

International Journal of Immunogenetics, Volume 50, Issue 6, Page 299-305, December 2023., 2023
Abstract Hepatitis B virus (HBV) is responsible for various liver diseases, such as chronic hepatitis B (CHB), liver fibrosis, liver cirrhosis (LC) and hepatocellular carcinoma (HCC), which pose a significant threat to human health. An ineffective immune response to HBV can result in viral chronicity.
Hai Cheng, Fenglan Sun, Yaoling Ouyang, Chengbin Li   +3 more
wiley   +1 more source

A Dual Co‐Reactant Accelerator Based On Nanoreactor‐Encapsulated CeO2 Nanozymes to Drive Potentiated Luminol Cathodic Electrochemiluminescence for Ultrasensitive Immunoassay

Rare Metals, Volume 45, Issue 5, May 2026.
ABSTRACT The precise quantification of cytokines is crucial for monitoring disease onset and progression. Herein, we developed a synergistic signal amplification approach by utilizing nanoreactor‐encapsulated CeO2 nanozymes, which were in situ electrodeposited within the mesoporous silica nanochannel film (SNF) grown on indium tin oxide (ITO ...
Yu Cui, Liuyi Huang, Jingwen Zhao, Jiyang Liu, Wei Hu   +4 more
wiley   +1 more source

Predictive value of gB2 antibodies for maternal–fetal transmission after primary cytomegalovirus infection treated with valacyclovir

Ultrasound in Obstetrics &Gynecology, Volume 67, Issue 4, Page 455-460, April 2026.
ABSTRACT Objective To estimate the residual risk of maternal–fetal transmission after primary cytomegalovirus (CMV) infection in the periconceptional period or the first trimester in women treated with valacyclovir, and to assess whether the presence of glycoprotein B2 (gB2)‐specific immunoglobulin (Ig)‐G antibodies on immunoblot analysis refines fetal
K. O. Kagan, A. L. Bissinger, O. Roth, J. Sonek, M. Hoopmann, Y. Ville, M. Enders   +6 more
wiley   +1 more source

Efficacy of Der f 2/Zen 1‐LAMP1 Plasmid‐Based Vaccine Immunotherapy in Dogs With Atopic Dermatitis: A Proof‐of‐Concept Study

Veterinary Dermatology, Volume 37, Issue 2, Page 306-318, April 2026.
Background: DNA‐based vaccination rapidly induces strong cellular and humoral immune responses, which may be enhanced by inclusion of lysosomal‐associated membrane protein‐1 (LAMP). Objectives: This proof‐of‐concept study evaluated the efficacy and safety of a Der f 2/Zen 1‐LAMP‐based DNA vaccine immunotherapy in client‐owned dogs with nonseasonal AD ...
Petra Bizikova, Chigusa Matsumoto, Shoji Ogino, Toshihiro Tsukui, Kim Love, Marcy Murphy, Ina Herrmann   +6 more
wiley   +1 more source

Lipid Nanoparticles Delivering ClpP‐mRNA Suppress Pyroptosis and Senescence in Intervertebral Disc Degeneration via mTOR/BNIP3‐Activated Mitophagy

Rare Metals, Volume 45, Issue 2, February 2026.
ABSTRACT Intervertebral disc degeneration (IDD) is a predominant cause of low back pain, significantly impacting quality of life. Mitochondrial fitness is essential in the progression of IDD, as it regulates cellular senescence and pyroptosis. This study investigates the role of mitochondrial caseinolytic protease P (ClpP) in alleviating senescence and
Kun Wang, Zhiqiang Wang, Tong Zhang, Shicheng Qiu, Guang Yang, Yanzheng Gao, Xiaofeng Lian, Xin Peng   +7 more
wiley   +1 more source