Results 21 to 30 of about 22,045 (162)
Rare Metals, Volume 45, Issue 1, January 2026.ABSTRACT Articular cartilage regeneration remains a significant challenge because of its limited intrinsic healing capacity and the inadequacy of conventional treatments for restoring structural and functional integrity. In this study, a novel injectable composite hydrogel scaffold was designed to mimic the extracellular matrix (ECM) of native ...
Zhong‐Lian Wu +13 more
wiley +1 more source
A new beef: An analysis of discourse coalitions in the nascent cellular agriculture policy subsystem
Review of Policy Research, Volume 42, Issue 6, Page 1404-1427, November 2025.Abstract A robust approach to examining the nature and influence of coalitions in the policy process is the Advocacy Coalition Framework (ACF), which is especially useful to study policy issues fraught with scientific and technical controversy. Yet, important gaps exist in ACF literature regarding nascent policy subsystems. Consequently, there is scant
Nikki Nadeau, Ramiro Berardo
wiley +1 more source
Dermoscopic evaluation of normal canine skin with a handheld dermoscope
Veterinary Dermatology, Volume 36, Issue 5, Page 593-601, October 2025.Background – Dermoscopy is a noninvasive diagnostic tool that provides a magnified view of skin structures. While dermoscopy is described for certain canine dermatological diseases, large‐scale studies evaluating normal skin are lacking. Hypothesis/Objective – This study aimed to correlate dermoscopic findings with histopathological results in healthy ...
Rachael Loek +4 more
wiley +1 more source
Updated insights into the molecular pathogenesis of canine atopic dermatitis
Veterinary Dermatology, Volume 36, Issue 4, Page 375-384, August 2025.Abstract Atopic dermatitis (AD) is a common and chronic inflammatory skin disease with frequent relapses. The genomics revolution has greatly contributed and revolutionised our knowledge of human AD; understanding the molecular skin fingerprint of AD and associated pathogenic immune pathways has led to preclinical assessments of several novel ...
Frane Banovic
wiley +1 more source
Systematic Entomology, Volume 50, Issue 3, Page 495-518, July 2025.Using genomic data from 285 species across 19 planthopper families, we conducted the first phylogenomic study targeting global planthoppers and inferred their phylogeny with the highest resolution so far. We proposed taxonomic changes including the establishment of a new family Borysthenidae stat. rev. and a new superfamily Meenoploidea superfam.
Junchen Deng +9 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2012 目的探讨白藜芦醇（Res）对人肾细胞癌786-0细胞中PDCD5蛋白表达的影响及PDCD5蛋白与白藜芦醇抑制人肾细胞癌786-0细胞生长的关系。方法分别采用12.5、25、50、100μmol/L的白藜芦醇（Res）作用于人肾细胞癌786-0细胞系24h.采用免疫细胞化学SP法检测PDCD5蛋白在肾细胞癌786-0细胞中的表达情况;采用流式细胞术检测肾细胞癌786-0细胞的增殖和凋亡情况。结果 Res呈剂量依赖性抑制人肾细胞癌786-0细胞的增殖;人肾细胞癌786-0细胞低水平表达PDCD5 ...
单中杰 +3 more
doaj
A Randomized Phase I/II Trial to Compare Weekly Usage with Triple Weekly Usage of Paclitaxel in Concurrent Radiochemotherapy for Patients with Locally Advanced Non-small Cell Lung Cancer [PDF]
, 2011 Background and objective Although the guidelines of the National Comprehensive Cancer Network of USA recommend that the standard therapy for locally advanced non-small cell lung cancer (LANSCLC) is concurrent chemoradiotherapy.
Anhui SHI +4 more
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Long‐term use of lokivetmab in dogs with atopic dermatitis
Veterinary Dermatology, Volume 35, Issue 6, Page 683-693, December 2024.Background – Lokivetmab, a caninised monoclonal antibody against interleukin (IL)‐31, is an effective treatment for the pruritus associated with canine atopic dermatitis (cAD). Objectives – To investigate the efficacy and safety of lokivetmab during long‐term treatment defined as at least three consecutive lokivetmab injections in atopic dogs under ...
Bettina Kasper +2 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 1999 目的探讨Rb蛋白的表达状况与肺癌细胞分类的关系及肺癌细胞癌变的机制。方法采用Westernblotting方法，检测人类13种小细胞肺癌、9种非小细胞肺癌细胞株Rb蛋白的表达。结果和结论10种小细胞肺癌细胞株存在Rb蛋白的缺失或变异，而非小细胞肺癌细胞株则无此改变，对具有较宽Rb带纹的3种小细胞肺癌和9种非小细胞肺癌细胞株进行了Rb蛋白分型，发现2种小细胞肺癌和7种非小细胞肺癌细胞株以磷酸化型Rb蛋白为主。
赵美蓉 +7 more
doaj
The spectrum-effect relationship study on Tripterygium Wilfordii glycoside tablet based on therapeutic effect and toxicity [PDF]
, 2015 雷公藤多苷片是由雷公藤的干燥根提取、纯化制得的，具有良好的抗炎、免疫抑制的药理作用，临床上广泛用于治疗类风湿关节炎、肾病综合征等疾病，疗效确切。但临床不良反应高发，且临床应用表明不同厂家的雷公藤多苷片药效和毒副反应有较大差异。由于雷公藤化学成分复杂，多个成分既为有效成分又为毒性成分，而目前多仅对雷公藤甲素(雷公藤内酯醇)或雷公藤内酯甲进行含量控制，无法全面的对雷公藤多苷片的药效和毒性进行控制。明确药效成分和毒性成分，建立全面科学、符合中药制剂整体起效特点的质量控制方法，是当前研究的热点和难点 ...
池婕
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