Results 11 to 20 of about 256,919 (167)
ABSTRACT This study introduces novel nonequiatomic TiZrCoCrMoCux (x = 0, 5, 10; at%) medium‐entropy alloys (MEAx) tailored for orthopedic implants, synergistically combining the biocompatibility of Ti‐based alloys, the wear resistance of CoCrMo alloys, and the antibacterial/osteogenic attributes of Cu. The alloy's microstructure, mechanical properties,
Hang Yu +9 more
wiley +1 more source
多核白细胞弹性蛋白酶对人角膜基质细胞MMP-2、MMP-9表达的影响
目的观察多核白细胞弹性蛋白酶与白细胞介素-1α对人角膜基质细胞表达的MMP-2、MMP-9的影响,进而探讨角膜溃疡的发生机理。方法体外培养人角膜基质细胞,在培养液中添加或不添加多核白细胞弹性蛋白酶或白细胞介素-1α,培养5天,通过明胶酶谱分析的方法测定培养上清中的MMP-2和MMP-9的表达。结果体外培养的人角膜基质细胞无任何刺激下可释放MMP-2;白细胞介素-1α可加强并激活MMP-2的表达,同时可诱导MMP-9前体的释放;多核白细胞弹性蛋白酶在白细胞介素-1α诱导下可完全激活前体MMP ...
刘泊明, 张冰洁, 杨贲, 郝继龙
doaj
ABSTRACT Articular cartilage regeneration remains a significant challenge because of its limited intrinsic healing capacity and the inadequacy of conventional treatments for restoring structural and functional integrity. In this study, a novel injectable composite hydrogel scaffold was designed to mimic the extracellular matrix (ECM) of native ...
Zhong‐Lian Wu +13 more
wiley +1 more source
目的探讨Rb蛋白的表达状况与肺癌细胞分类的关系及肺癌细胞癌变的机制。方法采用Westernblotting方法,检测人类13种小细胞肺癌、9种非小细胞肺癌细胞株Rb蛋白的表达。结果和结论10种小细胞肺癌细胞株存在Rb蛋白的缺失或变异,而非小细胞肺癌细胞株则无此改变,对具有较宽Rb带纹的3种小细胞肺癌和9种非小细胞肺癌细胞株进行了Rb蛋白分型,发现2种小细胞肺癌和7种非小细胞肺癌细胞株以磷酸化型Rb蛋白为主。
赵美蓉, 王杨, 裴瑞莲
doaj
A new beef: An analysis of discourse coalitions in the nascent cellular agriculture policy subsystem
Abstract A robust approach to examining the nature and influence of coalitions in the policy process is the Advocacy Coalition Framework (ACF), which is especially useful to study policy issues fraught with scientific and technical controversy. Yet, important gaps exist in ACF literature regarding nascent policy subsystems. Consequently, there is scant
Nikki Nadeau, Ramiro Berardo
wiley +1 more source
目的探讨Rb蛋白的表达状况与肺癌细胞分类的关系及肺癌细胞癌变的机制。方法采用Westernblotting方法,检测人类13种小细胞肺癌、9种非小细胞肺癌细胞株Rb蛋白的表达。结果和结论10种小细胞肺癌细胞株存在Rb蛋白的缺失或变异,而非小细胞肺癌细胞株则无此改变,对具有较宽Rb带纹的3种小细胞肺癌和9种非小细胞肺癌细胞株进行了Rb蛋白分型,发现2种小细胞肺癌和7种非小细胞肺癌细胞株以磷酸化型Rb蛋白为主。
赵美蓉 +7 more
doaj
Dermoscopic evaluation of normal canine skin with a handheld dermoscope
Background – Dermoscopy is a noninvasive diagnostic tool that provides a magnified view of skin structures. While dermoscopy is described for certain canine dermatological diseases, large‐scale studies evaluating normal skin are lacking. Hypothesis/Objective – This study aimed to correlate dermoscopic findings with histopathological results in healthy ...
Rachael Loek +4 more
wiley +1 more source
目的探讨白藜芦醇(Res)对人肾细胞癌786-0细胞中PDCD5蛋白表达的影响及PDCD5蛋白与白藜芦醇抑制人肾细胞癌786-0细胞生长的关系。方法分别采用12.5、25、50、100μmol/L的白藜芦醇(Res)作用于人肾细胞癌786-0细胞系24h.采用免疫细胞化学SP法检测PDCD5蛋白在肾细胞癌786-0细胞中的表达情况;采用流式细胞术检测肾细胞癌786-0细胞的增殖和凋亡情况。结果 Res呈剂量依赖性抑制人肾细胞癌786-0细胞的增殖;人肾细胞癌786-0细胞低水平表达PDCD5 ...
单中杰 +3 more
doaj
Updated insights into the molecular pathogenesis of canine atopic dermatitis
Abstract Atopic dermatitis (AD) is a common and chronic inflammatory skin disease with frequent relapses. The genomics revolution has greatly contributed and revolutionised our knowledge of human AD; understanding the molecular skin fingerprint of AD and associated pathogenic immune pathways has led to preclinical assessments of several novel ...
Frane Banovic
wiley +1 more source
Using genomic data from 285 species across 19 planthopper families, we conducted the first phylogenomic study targeting global planthoppers and inferred their phylogeny with the highest resolution so far. We proposed taxonomic changes including the establishment of a new family Borysthenidae stat. rev. and a new superfamily Meenoploidea superfam.
Junchen Deng +9 more
wiley +1 more source

