Results 11 to 20 of about 14,233 (155)
Highlights High stress hyperglycemia ratio (SHR) was associated with elevated systematic inflammation in diabetic inpatients with pneumonia on admission. In the absence of hypoglycemia on admission, SHR was of J‐shaped associations with adverse clinical outcomes in diabetic inpatients with pneumonia of different severity.
Bing Liu, Yu Chen, Liping Yu, Min Zhou
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Highlights For distinguishing glucokinase maturity‐onset diabetes of the young (GCK‐MODY) from hepatocyte nuclear factor 1‐α MODY (HNF1A‐MODY), total triglycerides may help during the follow‐up period. In order to discriminate GCK‐MODY from MODY‐like type 2 diabetes, high‐sensitivity C‐reactive protein may be a suitable indicator in the early stage ...
Jing Liu +3 more
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Highlights To our knowledge, our study is the first to date to investigate the association between metabolically defined obesity and adverse outcomes in patients with chronic myeloid leukemia (CML). Metabolic abnormalities were associated with adverse outcomes in patients with CML, irrespective of obesity status.
Yingchun Dong +11 more
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Highlights Red blood cell (RBC) lifespan variation, is the main cause of variation in glycosylated hemoglobin (HbA1c), independent of blood glucose levels. This study highlighted the important impact of RBC lifespan on HbA1c test value in T2DM with HbA1c test value <7%. We discovered that the HbA1c test value in type 2 diabetes (T2DM) patients with RBC
Junmei Wang +6 more
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Background– Cannabidiol (CBD) and cannabidiolic acid (CBDA) are reported to have antinociceptive, immunomodulatory and anti‐inflammatory actions. Objectives – To determine if CBD/CBDA is an effective therapy for canine atopic dermatitis (cAD). Conclusions and clinical relevance – Cannabidiol/CBDA as an adjunct therapy decreased pruritus, and not skin ...
Melissa Loewinger +4 more
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Onset and duration of action of lokivetmab in a canine model of IL‐31 induced pruritus
Onset of antipruritic action of lokivetmab in dogs. Laboratory‐bred beagle dogs were dosed subcutaneously with either placebo or lokivetmab at 2.0 mg/kg on Day (D) 0. Approximately 2.5 h post‐dosing, pruritus was induced using canine interleukin (IL)‐31. Animals were observed for pruritic behaviours for a total of 2 h (3–5 h post‐treatment with placebo
Timothy J. Fleck +6 more
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目的 本国际临床指南由欧洲残疾儿童学会(the European Academy of Childhood Disability,EACD)牵头制定,旨在解决发育性协调障碍(developmental coordination disorder,DCD)的定义、诊断、评估、干预以及与社会心理方面的临床应用关键问题。 方法 本指南针对五个领域的关键问题,通过文献综述和专家团队的正式讨论达成共识。为保证指南的循证基础,以“机制”、“评估”和“干预”为检索词, 对2012年更新以来提出的最新建议以及新增的“社会心理问题”和“青少年/成人”为检索词进行检索。根据牛津大学循证医学中心证据等级 (证据水平 [level of evidence, LOE]1–4) 将结果进行分类,最终转化为指南建议。并由国际 ...
Jing Hua +6 more
wiley +1 more source
胆漏的位置可能是影响首次内镜逆行胰胆管造影术成功的相关因素 [PDF]
目的探究胆漏的位置可能是影响首次内镜逆行胰胆管造影术(ERCP)成功的相关因素。方法回顾性分析广州医科大学附属第二医院自2012年6月至2017年4月行肝胆手术后疑似胆漏患者的临床资料。所有患者均行ERCP,分为胆囊管漏组(9例)和肝内胆管漏组(10例),统计分析白细胞计数、肝功能变化及治愈情况。结果19例患者均顺利完成治疗,术后未出现出血、穿孔、感染休克等严重并发症。两组患者手术前后白细胞计数、肝功能及改善情况比较差异无统计学意义(P>0.05)。把首次ERCP成功者分为A组(n=11 ...
曹良启, 陈世荣, 魏章均
core
Effects of Polybrominated Diphenyl Ethers on the Human Body Exposure in E-Waste Dismantling Region [PDF]
Objective To discuss the effects of polybrominated diphenyl ethers (PBDEs) exposure in e-waste dismantling region on the human body and provide data support for the identification of environmental health damage to residents in the e-waste dismantling ...
ZHOU Yan, Lü Shao-min, XIAO Jian-peng, et al
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Multi-system infection caused by Cryptococcus gattii in a non-immunocompromised patient: a case report [PDF]
Cryptococcus is a dimorphic opportunistic pathogenic fungus. Cryptococcal infection mostly occurs in immunocompromised patients infected with HIV, organ transplantation, long-term use of cortisol hormone, chemotherapy, chronic leukemia and lymphoma, etc.
Liao Wei, Sun Long
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