Results 61 to 70 of about 14,233 (155)
Correlation of peripheral blood ZO⁃1 and IL⁃38 levels with lung injury degree in patients with acute respiratory distress syndrome [PDF]
Objective To analyze the changes of zonula occludens⁃1（ZO⁃1）and interleukin⁃38（IL⁃38）levels in peripheral blood of acute respiratory distress syndrome（ARDS）patients with different degrees of lung injury，and their correlations with the degree of lung ...
HE Yanxia，XUE Bing，WU Wenjie，CHEN Xing
core +2 more sources
Zhongshan Daxue xuebao. Yixue kexue ban, 2008 [目的] 探讨Bmi-1引起中心体扩增的可能机制。[方法] 体外建立Bmi-1稳定高表达和Bmi-1–RNAi稳定起作用的细胞株， 采用免疫荧光染色法计数中心体（Microtub）异常复制的比率及定位细胞周期素蛋白D1（cyclinD1）和P27的表达，同时进行Western blot检测cyclinD1和p27在核中的表达量。[结果] Microtub染色计数发现与对照细胞相比，中心体异常复制的比率在6-10B/Bmi-1-1细胞中升高，而在CNE2/Bmi-1-RNAi细胞中下降 ...
翁桂香 +7 more
doaj
槲皮素对骨肉瘤细胞MG-63细胞色素C、Bcl-2及bax表达影响
Zhongguo shiyan zhenduanxue, 2018 目的探讨槲皮素(Quercetin)对人骨肉瘤细胞系MG-63细胞色素C、Bcl-2及bax表达影响。方法将处于对数生长期的MG-63细胞分为对照组和40μmol/L槲皮素处理组,用二步法RT-qPCR法检测各组细胞Bcl-2和bax表达;Western blot分析Bcl-2、bax及细胞色素C。结果与对照组比较,槲皮素处理组MG-63细胞Bcl-2mRNA及蛋白表达量明显降低,bax mRNA及蛋白表达量明显增加,差异均有统计学意义 ...
张静玲, 王克利, 闫双宝
doaj
Associations between serum complement component 3a and sC5b⁃9 levels with the prognosis of sepsis patients [PDF]
"Objective To investigate the associations of serum complement component 3a（C3a）and soluble terminalcomplement complex C5b⁃9（sC5b⁃9）levels with the severity of sepsis and 28⁃day clinical prognosis among patients，and to provide new biomarker references ...
SU Yixing，BAO Lei，YU Jun'an，GU Zhijian
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miR-135a靶向调控STAT6对前列腺癌细胞生物学行为的影响
Zhongguo shiyan zhenduanxue, 2020 目的分析微小RNA-135a(miR-135a)靶向调控信号传导和转录激活因子6(STAT6)对前列腺癌细胞生物学行为的影响。方法选取DU145前列腺癌细胞株,细胞培养后分为空白组、miR-135a阴性对照组、miR-135a转染组,构建miR-135a慢病毒载体,空白组加入常规细胞培养液、生理盐水做空白处理,miR-135a阴性对照组加入miR-135aNC、Lipofectamine 2000试剂行无义序列转染,miR-135a转染组加Hsa-miR-135a、Lipofectamine ...
赵宇明, 张悦, 代亮, 张立民
doaj
Association of ambient air pollutants with blood physiological and biochemical indicators and systemic immune inflammation index in people living around Beijing: an analysis of air pollution and population health data [PDF]
ObjectiveTo investigate the association of ambient air pollutants with blood physiological and biochemical indicators and systemic immune inflammation index in people living around the Beijing metropolitan area and to provide a basis for formulating ...
Bingqian DU +3 more
core +1 more source
Evaluation of machine learning prediction of altered inflammatory metabolic state after neoadjuvant therapy for breast cancer [PDF]
Objective·To develop a machine learning approach for early identification of metabolic syndromes associated with inflammatory metabolic state changes in breast cancer patients after neoadjuvant therapy, using common laboratory and transthoracic ...
CHAI Yezi +7 more
core +1 more source
Zhongguo shiyan zhenduanxue, 2007 目的观察低剂量丝裂霉素C（MMC）对辐射损伤小鼠外周血白细胞数变化及染色体畸变的影响。方法小鼠腹腔注射低剂量MMC,再给大剂量X射线照射,或先给大剂量X射线照射再给低剂量MMC。观察小鼠白细胞计数及骨髓细胞染色体畸变。结果所有低剂量MMC处理组小鼠骨髓细胞染色体畸变率均低于单纯大剂量照射组,且低剂量MMC处理组的白细胞数降低程度均较单纯照射组有所减轻。结论低剂量MMC可以减轻辐射所致的染色体损伤,具有辐射防护作用。
高峰 +5 more
doaj
, 2015 目的促进临床药师更好开展药学服务工作。方法总结临床药师临床实践的经验,并对部分典型病例进行分析。结果临床药师通过药学问诊和医嘱审核参与患者个体化用药,关注药品不良反应和药物相互作用,提供药学信息,对患者进行用药指导和出院用药教育,参与医师门诊开展药学服务。结论临床药师提供药学服务应找准切入点 ...
孙洲亮, 李彦萍
core
Zhongguo shiyan zhenduanxue, 2014 目的探讨支原体和细菌感染患儿外周血白细胞VCS参数的变化及临床意义。方法采用Coulter LH750全自动血细胞分析仪,测定120例支原体、细菌感染患儿和60例健康儿童的白细胞VCS参数,并对测定结果进行统计学分析。结果与健康对照组比较,支原体感染组的WBC,MNV,NDW,MNC,MLC,MLS,MMV,MDW和MMC明显增高,而MNS和MMS明显降低 ...
崔颖 +5 more
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