Results 11 to 20 of about 29,532 (167)

Decreased in n‐3 DHA enriched triacylglycerol in small extracellular vesicles of diabetic patients with cardiac dysfunction 糖尿病合并心脏功能障碍患者细胞外小囊泡中n‐3 DHA 富集的三酰甘油减少

Journal of Diabetes, Volume 15, Issue 12, Page 1070-1080, December 2023., 2023
Highlights Lipid profiles of small extracellular vesicles (sEVs) in patients with diabetes or diabetic cardiovascular disease are rarely reported. n‐3 docosahexaenoic acid (DHA)‐enriched triacylglycerol (TG) was found to decrease in sEVs from serum of patients with diabetic cardiovascular disease (DM‐CAD).
Wei Ding, Xuejuan Zhang, Dandan Xiao, Wenguang Chang   +3 more
wiley   +1 more source

Fatty acid β‐oxidation and mitochondrial fusion are involved in cardiac microvascular endothelial cell protection induced by glucagon receptor antagonism in diabetic mice 脂肪酸β‐氧化和线粒体融合参与胰高血糖素受体拮抗剂对糖尿病小鼠心脏微血管内皮细胞的保护作用

Journal of Diabetes, Volume 15, Issue 12, Page 1081-1094, December 2023., 2023
Highlights Glucagon receptor (GCGR) monoclonal antibody (mAb) improves cardiac function and attenuates microvascular damage in db/db mice. GCGR mAb ameliorates the oxidative stress of cardiac microvascular endothelial cells in diabetic mice. GCGR mAb counteracts the diabetes‐induced upregulation of carnitine palmitoyltransferase 1B, optic atrophy type ...
Peng Wang, Rui Wei, Xiaona Cui, Zongzhe Jiang, Jin Yang, Lingyun Zu, Tianpei Hong   +6 more
wiley   +1 more source

Sensitivity of a Hymenoptera serological immunoglobulin (Ig)E assay for the diagnosis of venom hypersensitivity in dogs

Veterinary Dermatology, Volume 34, Issue 6, Page 543-553, December 2023., 2023
Background – Hymenoptera envenomation with honey bee (Apis mellifera) and paper wasp (Polistes spp.) may cause life‐threatening anaphylaxis in dogs. In human patients, clinical history, intradermal testing (IDT) and measurement of allergen‐specific serological immunoglobulin (Ig)E (sIgE) are used to support a diagnosis of Hymenoptera venom ...
Hilary H. Chan, Amanda K. Burrows, Giselle Hosgood, Rudayna Ghubash   +3 more
wiley   +1 more source

Exosomal miR‐let‐7c‐5p is involved in the cognitive function of type 2 diabetes mellitus patients by interleukin 10: A cross‐sectional study 外泌体miR‐let‐7c‐5p通过白细胞介素10参与2型糖尿病患者的认知功能:一项横断面研究

Journal of Diabetes, Volume 15, Issue 11, Page 978-986, November 2023., 2023
Highlights Both interleukin‐10 levels and exosomal miR‐let‐7c‐5p levels are correlated with cognitive function in patients with type 2 diabetes mellitus. There is a negative association between interleukin‐10 levels and exosomal miR‐let‐7c‐5p levels in the plasma of patients with type 2 diabetes mellitus. Abstract Background Interleukin (IL)‐10 plays a
Hui Zhang, Shufang Yang, Wenwen Zhu, Tong Niu, Jue Wang, Mingyue Yang, Enlin Liu, Jumei Wang, Sumei Li, Haoqiang Zhang   +9 more
wiley   +1 more source

Successful surgical removal of a pheochromocytoma in a mare via trans‐costal approach

Equine Veterinary Journal, Volume 55, Issue 6, Page 1012-1020, November 2023., 2023
Abstract Background Pheochromocytomas have been previously reported in horses, but successful antemortem diagnosis and surgical removal without recurrence of clinical signs have not been described. Objective To report the clinical presentation, diagnostic evaluation, surgical technique, anaesthetic management and post‐operative care of a mare diagnosed
Thomas J. O'Brien, Lynn M. Pezzanite, Elizabeth V. Acutt, Allison C. Vilander, Diana M. Hassel, Rachel C. Hector, Dean A. Hendrickson   +6 more
wiley   +1 more source

5-フルオウラシル投与により悪性変化するGATA1関連白血病の白血病幹細胞 [PDF]

, 2009
筑波大学University of Tsukuba博士（医学）Doctor of Philosophy in Medical Sciences2009Joint authors: Ritsuko Shimizu ... [et al.]Offprint. Originally published in: Experimental hematology, v. 37, issue 4 (Apr. 2009), pp.
73896, 安部, 加奈子
core   +1 more source

Glycosylated fibronectin improves first‐trimester prediction of pre‐eclampsia

Ultrasound in Obstetrics &Gynecology, Volume 62, Issue 4, Page 512-521, October 2023., 2023
ABSTRACT Objective To determine whether maternal serum glycosylated fibronectin (GlyFn) level in the first trimester increases the sensitivity of the Fetal Medicine Foundation (FMF) triple test, which incorporates mean arterial pressure, uterine artery pulsatility index and placental growth factor, when screening for pre‐eclampsia (PE) in an Asian ...
S. Moungmaithong, X. Wang, C. S. L. Lau, A. W. T. Tse, N. M. W. Lee, H. H. Y. Leung, L. C. Poon, D. S. Sahota   +7 more
wiley   +1 more source

Original Article [PDF]

, 2016
本研究の目的は,健康な小児ががんや白血病といった病名からどのようなイメージを抱くのか,自分が大きな病気になったとしたら,病名や治療などについて教えて欲しいと思っているのかを明らかにすることである。千葉県内の小中高校に通っている小学校5年生から高校3年生までの児童生徒1964名から得られたアンケートの回答を,統計ソフトSPSSにて分析を行い以下の結果を得た。1.健康な小児が抱くがんのイメージは,「死ぬ・治らない」「重い・危険・苦しい」といった悲観的なのものが多く,全体の約65%を占めていた ...
Crosby, William L., Dezfulian, Mohammad H., Jalili, Espanta, Khoo, Kerry, Moss, Britney L., Nemhauser, Jennifer L., Roberto, Don Karl A.   +6 more
core   +5 more sources

小児造血器腫療の完全治癒をめざして : 小児癌・白血病研究グループの治療戦略と成績 [PDF]

, 1991
小児期白血病は化学療法に対してきわめて高い感受性をもち， “癌を薬物で完治させる” という治癒的化学療法（ curative chemotherapy ） の最前線にある。この白血病患児の長期完全寛解例の増加は従来の致死的疾患の概念から治療可能で、治癒できる疾患へと変貌し， 治療方針も寛解指向型から治癒指向型へと変換されている。しかもなお生存の意味において， 子どもは癌（白血病）から解放された後も40 ～50年以上の長い人生を歩いていかねばならない。子どもは治療期間中も身体的にも精神・情緒面でも，発育 ...
藤本 孟男
core   +1 more source

Roles of TIF1β in Leukemic Stem Cell Through SETDB1‐Dependent and Independent Mechanisms

Cancer Science, EarlyView.
In leukemic stem cell, BCR::ABL cooperates with TIF1β to open chromatin at oncogenes and close chromatin at differentiation regulators, driving leukemic reprogramming. In TIF1β‐deficient stem cell, the loss of TIF1β inverts this balance, showing closed chromatin at oncogenes and open chromatin at differentiation regulators.
Mariko Morii, Sho Kubota, Goro Sashida
wiley   +1 more source