Results 31 to 40 of about 43,834 (216)

Analysis of the immunomodulatory properties of mycobacterium cell wall fraction on the cytokine production of peripheral blood mononuclear cells of healthy dogs

open access: yesVeterinary Dermatology, Volume 35, Issue 6, Page 595-604, December 2024.
Background – Mycobacterium cell wall fraction (MCWF) is derived from nonpathogenic Mycobacterium phlei and is used as an immunomodulatory compound in clinical practice, yet its mode‐of‐action requires further research. Objective – To evaluate the host response to MCWF in canine peripheral blood mononuclear cells (PBMCs) by using enzyme‐linked ...
Robert Ward   +9 more
wiley   +1 more source

糖化血红蛋白、同型半胱氨酸及尿微量白蛋白与2型糖尿病合并肾脏微血管病变的关系研究

open access: yesZhongguo shiyan zhenduanxue, 2015
目的探讨糖化血红蛋白、同型半胱氨酸及尿微量白蛋白与2型糖尿病肾脏微血管病变的关系。方法选择95例2型糖尿病患者作为观察组研究对象,同期来医院参加体检的健康志愿者作为对照组,检测研究对象的糖化血红蛋白、同型半胱氨酸和尿微量白蛋白及血生化指标,分析比较各组糖化血红蛋白、同型半胱氨酸及尿微量白蛋白水平。结果糖尿病合并肾脏微血管病变组研究对象的糖化血红蛋白、同型半胱氨酸及尿微量白蛋白水平高于单纯糖尿病组患者和对照组研究对象,同型半胱氨酸随血糖升高、肾脏损害程度的加深而升高,差异有统计学意义 ...
亓海萍, 吕卫华, 武琳
doaj  

Combined first‐trimester screening and invasive diagnostics for atypical chromosomal aberrations: Danish nationwide study of prenatal profiles and detection compared with NIPT

open access: yesUltrasound in Obstetrics &Gynecology, Volume 64, Issue 4, Page 470-479, October 2024.
ABSTRACT Objectives Our aim was to examine the prenatal profiles of pregnancies affected by an atypical chromosomal aberration, focusing on pathogenic copy‐number variants (pCNVs). We also wanted to quantify the performance of combined first‐trimester screening (cFTS) and a second‐trimester anomaly scan in detecting these aberrations. Finally, we aimed
K. Gadsbøll   +6 more
wiley   +1 more source

C-kit原癌基因在白血病细胞上的表达分析

open access: yesZhongguo shiyan zhenduanxue, 2004
目的 研究C kit(CD117)原癌基因在白血病细胞上的表达规律和意义。方法 采用CD4 5 SSC双参数 (对数 )散点图设门法进行三色流式细胞术分析。结果 急性髓细胞白血病 (AML)患者CD117表达率为 5 9 6 % ;慢性髓细胞白血病 (CML)CD117表达率为 16 7% ,且都为急变期 ;急性淋巴细胞性白血病 (ALL)极少表达 ,慢性淋巴细胞性白血病 (CLL)不表达 ;干细胞性白血病 (AUL)、双表型白血病 (BAL)高表达。结论 CD117有助于鉴别诊断髓系白血病 ...
陈葆国   +3 more
doaj  

Maternal antenatal depression, oxytocin, and infant temperament: The roles of ethnicity and adult attachment avoidance

open access: yesInfant Mental Health Journal: Infancy and Early Childhood, Volume 45, Issue 5, Page 516-528, September 2024.
Abstract This study examined the associations between maternal depression and oxytocin in pregnancy, caregiving sensitivity and adult attachment style, and infant temperament. One hundred and six women recruited from a public hospital antenatal clinic in Australia, and their infants completed assessments at three time points (Time 1: pregnancy; Time 2:
Jane Kohlhoff   +5 more
wiley   +1 more source

白血病基因诊断及其信息系统建立

open access: yesZhongguo shiyan zhenduanxue, 2006
目的用基因诊断技术对白血病分型诊断及微小残留病(MRD)监控,同时对所检测数据建立信息系统。方法巢式RT-PCR扩增急髓性白血病融合基因,PCR扩增急性淋巴细胞白血病基因重排,用Delphi程序设计信息系统。结果M2b型白血病能扩增出AML1/ETO融合基因;M3型白血病能检测出L型和S型融合基因;慢粒白血病可检测出b3a2和b2a3融合基因;急淋白血病可检测出IgH、TCRγ、TCRδ基因重排。结论基因诊断能有效进行白血病分型及MRD监控,信息系统的建立方便了检测信息的管理及查询。
孙新六
doaj  

Maternal ethnicity and socioeconomic deprivation: influence on adverse pregnancy outcomes

open access: yesUltrasound in Obstetrics &Gynecology, Volume 64, Issue 2, Page 187-192, August 2024.
ABSTRACT Objective To evaluate the relative importance of ethnicity and socioeconomic deprivation in determining the likelihood and prevalence of placentally derived composite of adverse pregnancy outcomes (CAPO) and composite of severe adverse pregnancy outcomes (CAPO‐S).
M. Minopoli   +5 more
wiley   +1 more source

原发性高血压肾病患者血清CRP、胱抑素C和尿微量白蛋白的变化及临床意义分析

open access: yesZhongguo shiyan zhenduanxue, 2015
目的探讨原发性高血压肾病患者血清CRP、胱抑素C和尿微量白蛋白的变化及临床意义。方法选取32例高血压肾病患者(高血压肾病组)、28例高血压无肾病患者(高血压无肾病组)及同期健康体检者(对照组)作为研究对象,比较尿常规生化指标、血清CRP、胱抑素C及尿微量白蛋白水平。结果高血压肾病组血清CRP、胱抑素C及尿微量白蛋白水平均明显高于对照组及高血压无肾病组,差异具有统计学意义(P0.05)。高血压肾病组治疗后血清CRP、胱抑素C及尿微量白蛋白水平明显低于治疗前 ...
赵杨
doaj  

Rituximab with standard LMB chemotherapy in pediatric high‐risk mature B‐cell non‐Hodgkin lymphoma: A report from the JPLSG B‐NHL14 trial

open access: yesEuropean Journal of Haematology, Volume 112, Issue 4, Page 585-593, April 2024.
Abstract Background The benefit of adding rituximab to standard lymphomes malins B (LMB) chemotherapy for children with high‐risk mature B‐cell non‐Hodgkin lymphoma (B‐NHL) has previously been demonstrated in an international randomized phase III trial, to which the Japanese Pediatric Leukemia/Lymphoma Study Group could not participate.
Tetsuya Mori   +12 more
wiley   +1 more source

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