Results 31 to 40 of about 29,532 (167)
Non - malignant elevation of Wilms tumor gene (WT1) expression is frequently observed in the blood and bone marrow of childhood acute leukemia in remission and in benign blood diseases [PDF]
筑波大学博士 (医学) 学位論文・平成21年3月25日授与 (甲第5112号 ...
中尾 朋平
core
ABSTRACT Objectives Our aim was to examine the prenatal profiles of pregnancies affected by an atypical chromosomal aberration, focusing on pathogenic copy‐number variants (pCNVs). We also wanted to quantify the performance of combined first‐trimester screening (cFTS) and a second‐trimester anomaly scan in detecting these aberrations. Finally, we aimed
K. Gadsbøll +6 more
wiley +1 more source
Abstract This study examined the associations between maternal depression and oxytocin in pregnancy, caregiving sensitivity and adult attachment style, and infant temperament. One hundred and six women recruited from a public hospital antenatal clinic in Australia, and their infants completed assessments at three time points (Time 1: pregnancy; Time 2:
Jane Kohlhoff +5 more
wiley +1 more source
Maternal ethnicity and socioeconomic deprivation: influence on adverse pregnancy outcomes
ABSTRACT Objective To evaluate the relative importance of ethnicity and socioeconomic deprivation in determining the likelihood and prevalence of placentally derived composite of adverse pregnancy outcomes (CAPO) and composite of severe adverse pregnancy outcomes (CAPO‐S).
M. Minopoli +5 more
wiley +1 more source
Abstract Background The benefit of adding rituximab to standard lymphomes malins B (LMB) chemotherapy for children with high‐risk mature B‐cell non‐Hodgkin lymphoma (B‐NHL) has previously been demonstrated in an international randomized phase III trial, to which the Japanese Pediatric Leukemia/Lymphoma Study Group could not participate.
Tetsuya Mori +12 more
wiley +1 more source
目的用基因诊断技术对白血病分型诊断及微小残留病(MRD)监控,同时对所检测数据建立信息系统。方法巢式RT-PCR扩增急髓性白血病融合基因,PCR扩增急性淋巴细胞白血病基因重排,用Delphi程序设计信息系统。结果M2b型白血病能扩增出AML1/ETO融合基因;M3型白血病能检测出L型和S型融合基因;慢粒白血病可检测出b3a2和b2a3融合基因;急淋白血病可检测出IgH、TCRγ、TCRδ基因重排。结论基因诊断能有效进行白血病分型及MRD监控,信息系统的建立方便了检测信息的管理及查询。
孙新六
doaj
探讨白血病患者骨髓中VEGF、bFGF、sICAM-1及CD105的表达对髓血屏障调节机制的影响
目的探讨白血病患者骨髓中VEGF、bFGF、sICAM-1及CD105的表达对髓血屏障调节机制的影响。方法采用原位杂交方法,用CD105标记骨髓活化的血管内皮细胞;用ELISA方法检测骨髓液VEGF、bFGF、sICAM-1的表达水平。结果 CD105在白血病的表达以急性髓系白血病(AML-M5)最高,急性髓系白血病(AML)AML-M3表达最低。AML-M5的阳性表达率为(52.32±15.34)%,明显高于正常对照组[(2.32±0.87)%](P0.05 ...
马传香 +4 more
doaj
Induction of differentiation of human myeloid leukemia cells by cytokinins, plant hormones [PDF]
急性骨髄性白血病はall trans-retinoic acidを投与することで治療することが可能である。この治療効果は分化誘導によることが明らかにされたことから,分化誘導機構の解明と,さらなる有効な分化誘導剤の開発が必要とされている。植物ホルモンのサイトカイニンは植物に多彩な生理作用をもたらすが,その一つに,カルスから不定芽を誘導し,植物体へと再分化させる活性がある。本論文は,カルス細胞とがん細胞は「増殖の盛んな未分化細胞であり,分化誘導が可能である」という類似点があることに着目し ...
Ishii Yuki, 石井 由起
core
目的: 观察白血病、再生障碍性贫血患者治疗前后巨细胞病毒( CMV) 、单纯疱疹病毒( HSV)、爱博斯坦巴尔病毒 ( EBV)的感染状况。方法: 用 PCR 法检测急性白血病患者骨髓单个核细胞内 CM V-DNA 、HSV-DNA、EBV-DNA, 以及再生障 碍性贫血患者血浆中 CM V-DNA 感染情况。结果: 急性白血病患者骨髓单个核细胞内 CMV-DNA 的检出率高于血浆的检出 率; 初治白血病患者骨髓单个核细胞内及初治再生障碍性贫血患者的血浆 CMV-DNA 阳性率分别为 73%和 54%,
李 娟 洪文德 罗绍凯 朱沃棠
doaj
目的探讨血糖波动与早期糖尿病肾病微量白蛋白尿之间的关系。方法对40例尿白蛋白排泄率(UAER)≤20μg/min(正常白蛋白尿组)及40例UAER 20-199μg/min(微量白蛋白尿组)的2型糖尿病患者进行动态血糖监测(CGMS),然后比较两组患者的平均血糖、平均血糖波动振幅(MAGE)及血糖标准差(SDBG)。结果两组患者的平均血糖水平(11.07±1.94 mmol/L vs 10.45±1.90 mmol/L)无统计学差异;微量白蛋白尿组,血糖标准差(3.14±0.94 mmol/L vs 2.
何扬芳 +3 more
doaj

