Results 11 to 20 of about 1,078,112 (127)

[Prognostic significance of early phase donor chimerism after allogeneic peripheral blood stem cell transplantation]. [PDF]

open access: yesZhonghua Xue Ye Xue Za Zhi, 2018
目的 评价清髓性异基因外周血干细胞移植(allo-PBSCT)后早期完全供者嵌合状态(FDC)对患者预后的预测意义。 方法 回顾性分析2016年2月至2017年7月行清髓性allo-PBSCT治疗的72例血液病患者临床资料。男44例,女28例,中位年龄36.5(4~59)岁。其中同胞全合供者35例、亲缘单倍型相合供者27例、无关供者10例。采用聚合酶链反应扩增短串联重复序列(PCR-STR)检测移植后1、2、3个月受者骨髓的供者细胞嵌合(DC)率。 结果 全部72例患者中位随访462(47~805)d ...
Zhai WH   +17 more
europepmc   +2 more sources

Genetic distribution and forensic evaluation of multiplex autosomal short tandem repeats in the Chinese Xinjiang Mongolian group

open access: yesJournal of Zhejiang University SCIENCE B, 2019
概要目的分析常染色体19 个短串联重复序列(STR)位点 在新疆蒙古族群体中的遗传多态性分布, 为其法 医学应用提供数据支持。创新点丰富了新疆蒙古族群体的常染色体STR 遗传数据。方法从新疆地区采集1133 个无血缘关系的蒙古族健康 个体, 应用一个包含常染色体19 个STR 位点的 复合扩增体系对这些样本进行基因分型检测。 同 时, 基于15 个共有的STR 位点, 采用多维尺度 分析、遗传距离(DA)和遗传分化系数(FST) 的方法探讨了新疆蒙古族群体和既往报道的20 个群体间的群体遗传关系 ...
Yuanyuan Wei   +8 more
semanticscholar   +1 more source

Yield gains in extra-early maize cultivars of three breeding eras under multiple environments [PDF]

open access: yes, 2017
Open Access JournalAvailability of extra-early maize cultivars has facilitated the expansion of maize production into savannas of West and Central Africa (WCA).
A. O. Talabi   +52 more
core   +2 more sources

中国海南黎族人群15 个STR 位点的遗传多态性

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2005
【目的】研究海南黎族族人群15个STR位点D3S1358、TH01、D21S11、D18S51、VWA、CSF1PO、D8S1179、TPOX、FGA、D5S818、D13S317、D7S820、D16S539、D19S433、D2S1338的遗传多态性。【方法】通过人类短串联重复序列(short tandem repeat,STR)复合扩增、基因扫描、基因分型调查了110名黎族无关个体15个STR位点等位基因分布情况。【结果】15个STR位点均符合Hardy-Weinberg平衡 ...
邓文国   +4 more
doaj  

Imaging electric fields in the vicinity of cryogenic surfaces using Rydberg atoms

open access: yes, 2015
The ability to characterize static and time-dependent electric fields in situ is an important prerequisite for quantum-optics experiments with atoms close to surfaces.
Agner, J. -A.   +6 more
core   +1 more source

A reference haplotype panel for genome-wide imputation of short tandem repeats. [PDF]

open access: yes, 2018
Short tandem repeats (STRs) are involved in dozens of Mendelian disorders and have been implicated in complex traits. However, genotyping arrays used in genome-wide association studies focus on single nucleotide polymorphisms (SNPs) and do not readily ...
Fotsing, Stephanie Feupe   +4 more
core   +3 more sources

X-连锁严重联合免疫缺陷病的植入前遗传学诊断

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2017
【目的】采用多重置换扩增建立一种可靠、准确的植入前遗传学诊断方法,应用于X-连锁严重联合免疫缺陷病 (X-SCID)的植入前遗传学诊断(PGD)。【方法】选择5个位于致病基因IL-2受体γ链(IL2RG)基因两侧的短串联重复序列 (STR)位点对X-SCID家系进行单体型分析,采用多重置换扩增(MDA)对单细胞进行全基因组扩增,对扩增产物采用在家 系分析中具有多态性的STR位点进行单体型分析,结合位点Amel进行性别诊断,STR位点均采用单重荧光PCR,同时对 ...
吴海涛   +7 more
doaj  

STR profiling and Copy Number Variation analysis on single, preserved cells using current Whole Genome Amplification methods [PDF]

open access: yes, 2017
The growing interest in liquid biopsies for cancer research and cell-based non-invasive prenatal testing (NIPT) invigorates the need for improved single cell analysis.
Cornelis, Senne   +5 more
core   +2 more sources

中国汉族群体DXS101 位点的多态性

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2001
【目的】调查X 染色体特异性位点DXS101 在中国汉族人群的多态性。【方法】利用PCR 和聚丙烯凝胶电泳对 短串联重复序列(short tandem repeat , STR)位点DXS101 进行分型, 并检验女性基因型频率分布是否符合Hardy-Weinberg 平 衡, 计算法医学常用各种概率。【结果】在147 名女性和150 名男性中国汉族无关个体共发现了8 个等位基因。等位基因的 频率分布在0.0133 ~ 0.2279 之间。正合检验表明女性的基因型频率分布符合Hardy ...
吕德坚   +3 more
doaj  

Authentication of newly established human esophageal squamous cell carcinoma cell line (YM-1) using short tandem repeat (STR) profiling method [PDF]

open access: yes, 2016
Cross-contamination during or early after establishment of a new cell line could result in the worldwide spread of a misidentified cell line. Therefore, newly established cell lines need to be authenticated by a reference standard method.
Ayyoob, K.   +3 more
core  

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