[Advances in Diagnosis and Targeted Therapy of KRASG12C Mutant Non-small Cell Lung Cancer]. [PDF]
Shi J, Wang Y, Zheng J, Zhou J.
europepmc +1 more source
[Myelodysplastic neoplasms with acute myeloid leukemia-like mutations: clinical features, molecular profiles, and prognosis]. [PDF]
Bao ZF +13 more
europepmc +1 more source
[Research Progress in Imaging Investigation of TERT Promoter Mutations in Gliomas]. [PDF]
Zhong Y +5 more
europepmc +1 more source
用E-PTA负染色和锇酸(O3 O4)处理普通透射电镜方法结合形态计量和体视学分析年青(3个月)和老年(27个月)SD大鼠海马CA1区分子层突触结构,结果显示衰老时海马CA1区突触形态结构发生了一系列退行性和代偿性变化:单位体积的突触数量(Nv),突触连接带总面积(Sv)明显减少,突触前终末内突触囊泡、线粒体数亦明显减少。突触后膜致密物厚度变薄,而突触接触带的平均长度则代偿性增大。突触间隙宽度,突触前终末剖面积,突触后终末棘器数无明显改变 ...
doaj
[Advances in Immunotherapy of KRAS-mutated Non-small Cell Lung Cancer]. [PDF]
Yang X, Tang Z, Ma L, Chen R.
europepmc +1 more source
[目的 l 构建人肝豆状核变性病ATP7B基因野生型及常见突变型的小鼠肝脏特异性表达载体 ALB-ATP7B, 为制备转基因小鼠及相关基因治疗作准备。【方法】定点突变法获取人群中常见的Arg778Leu及 Hisl069Gln两种ATP7B基因突变体,定向克隆将小鼠白蛋白启动子ALB序列及野生和突变的ATP7B基因亚克 隆至真核表达载体kbpala上, 得到可在小鼠肝脏特异性表达的人ATP7B基因正常及突变型真核表达载体 ALB-ATP7B。【结果】经测序及酶切鉴定证实, 真核表达载体ALB ...
doaj
[Heterogeneity in the regulation of cellular stress responses by <i>FUS</i> gene mutations associated with amyotrophic lateral sclerosis]. [PDF]
Yu C +5 more
europepmc +1 more source
Physiological analysis of fruit ripening mutants and their application in breeding for long shelf-life [PDF]
Lu, C, Xu, H, Yang, R, Yu, W
core
[Lung Adenocarcinoma with EGFR Exon 20 H773_V774delinsLM Mutation Sensitive to Furmonertinib: A Case Report]. [PDF]
Li R +5 more
europepmc +1 more source
[Identification of SORD as A Key Gene Mediating Osimertinib Primary Resistance in EGFR-Mutant Lung Adenocarcinoma via Machine Learning and Methylomics]. [PDF]
Liang G +8 more
europepmc +1 more source

