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EGFR-TKIs治疗非小细胞肺癌EGFR罕见突变的研究进展

Zhongguo fei ai za zhi = Chinese journal of lung cancer, 2019
肺癌是目前最常见的癌症,也是导致癌症死亡的首要原因。非小细胞肺癌(non-small cell lung cancer, NSCLC)占85%以上,且高达50%的亚洲NSCLC患者携带表皮生长因子受体(epidermal growth factor receptor, EGFR)基因突变。研究证明,伴有EGFR突变的NSCLC患者接受表皮生长因子受体-酪氨酸激酶抑制剂(epidermal growth factor receptor-tyrosine kinase inhibitors, EGFR ...
Wenxing Du   +4 more
semanticscholar   +1 more source

肿瘤突变负荷对肺癌免疫治疗疗效的预测价值

Zhongguo fei ai za zhi = Chinese journal of lung cancer, 2019
肺癌的发病率和死亡率居全球首位,除化疗、放疗和靶向治疗外,免疫治疗也成为其不容忽视的治疗策略。美国食品药品监督管理局(Food and Drug Administration, FDA)相继批准免疫检查点抑制剂作为晚期非小细胞肺癌(non-small cell lung cancer, NSCLC)二线治疗和部分患者一线治疗的标准方案。美国国家综合癌症网(National Comprehensive Cancer Network, NCCN)也推荐免疫检查点抑制剂用于复发小细胞肺癌(small cell
Huanlan Sa   +3 more
semanticscholar   +1 more source

Usher综合征1型家系 PCDH15 基因的突变分析与产前诊断

, 2020
李亚娟   +9 more
semanticscholar   +1 more source

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