Results 51 to 60 of about 362 (104)
野生动物学报线粒体DNA（mtDNA）的异质性（heteroplasmy）是多种不同序列的mtDNA拷贝共存于一个个体的现象，对线粒体、细胞和组织的机能产生明显的影响。粪便是野生动物研究中最易得的材料，含有动物肠上皮脱落的细胞及其DNA，其中的mtDNA异质性可以反映个体在各种因素影响下肠上皮细胞DNA的稳定性，为揭示个体的适合度、生态对策等提供新的线索。梅花鹿（Cervus nippon）是森林生态系统中的关键物种，其肠上皮中mtDNA异质性的特点尚未见报道。本研究用27只6～96月龄的圈养梅花鹿粪便样本 ...
高雨薇 +10 more
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Zhongguo shiyan zhenduanxue结直肠癌（Colorectal cancer，CRC）是全球高发病率和高死亡率的恶性肿瘤之一，早期诊断对改善患者预后至关重要。然而，传统诊断方法如结肠镜检查和粪便潜血试验（Fecal occult blood test，FOBT）存在侵入性、灵敏度不足等局限性。水凝胶微珠技术因其优异的生物相容性、高负载能力和可调控的物理化学性质，在 CRC早期无创诊断中展现出巨大潜力。本文综述了水凝胶微珠的技术原理、制备方法（如微流体技术、乳化法、电喷雾、光刻法和 3D打印）及其在 CRC核酸标志物（如基因突变、甲基化
王少妍, 秦宇, 付渤钧, 张海山
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[<i>Streptococcus salivarius</i>-derived extracellular vesicles exacerbate progression of lupus nephritis by activating natural killer cells]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoXiao J, Jin L, Duan L, Gong Y, Li H.
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[Relationship between chronic radiation enteritis of cervical cancer and gut microbiota]. [PDF]
Beijing Da Xue Xue Bao Yi Xue Ban, 2023 Jiang HH, Li XF, Wang JL.
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[Dynamic changes in gut microbiota from 1 to 12 months of age in preterm infants]. [PDF]
Zhongguo Dang Dai Er Ke Za ZhiSong QY, Zhao XL, Ding BL, Lyu Q, Ma LY.
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野生动物学报为了探究秦岭大熊猫（Ailuropoda melanoleuca qinlingensis）圈养种群的遗传多样性和亲子关系，指导其科学繁育，本研究建立了一套优化的技术体系。利用筛选出的9个高分辨率微卫星位点（以四碱基重复为主）进行PCR扩增与毛细管电泳分型，并对32只个体进行遗传多样性分析。结果显示：通过均质化与热孵育预处理，显著提升了粪便样本中宿主基因组DNA的得率与质量。秦岭大熊猫群体Ho为0.281 ~0.938，平均为0.596，He为0.391 ~ 0.793，平均为0.560， Ho >
刘晨阳 +8 more
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[Differential analysis of gut microbiome in patients with periprosthetic joint infection, aseptic failure, and osteoarthritis]. [PDF]
Zhongguo Xiu Fu Chong Jian Wai Ke Za ZhiMuzhabaier K +6 more
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[Detection and Distribution Characteristics of Antibiotic Resistance Genes in Companion Animals]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue BanWang R, An L, Pei X, Chen J.
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[Changes of gut microflora in newly diagnosed IgA nephropathy patients and its correlation with clinical risk factors]. [PDF]
Beijing Da Xue Xue Bao Yi Xue Ban, 2023 Bao WH, Tang W.
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