Results 31 to 40 of about 668,371 (153)
基于lcms代谢组学技术的注射用黄芪多糖活性成分调控巨噬细胞代谢研究
, 2020 目的采用LC-MS代谢组学方法,研究注射用黄芪多糖活性成分对小鼠单核巨噬细胞白血病细胞Raw 264.7吞噬活性的影响。方法采用中性红法检测注射用黄芪多糖中不同相对分子质量多糖对Raw 264.7细胞吞噬活性的影响,筛选出活性成分,并对细胞培养液和细胞裂解液进行LC-MS分析,结合多元统计分析和代谢通路分析,探索其作用机制。结果注射用黄芪多糖的小相对分子质量多糖在质量浓度为30 μg/mL时能显著增强Raw 264.7细胞的吞噬活性。与对照组比较,注射用黄芪多糖活性成分作用于Raw 264.7细胞后 ...
李树颖 +4 more
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, 2019 介绍针灸促进胃黏膜损伤修复的代谢机制,重点从针灸在胃黏膜损伤修复的氨基酸代谢、脂代谢、糖代谢等几个方面探讨其机理,认为针灸可通过调节以上3个方面的代谢途径实现胃黏膜修复,并提出代谢组学在中医应用的展望。广东省自然科学基金项目(2017A030313748)深圳市卫生计生委科研项目(201607061)深圳市福田区卫生公益性科研项目 ...
杨宗保, 杨锦兰, 冯军, 谢宇锋
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Effects of Mepiquat Exposure on Rat Urine Based on Metabolomics(基于代谢组学分析缩节胺暴露对大鼠尿液的影响) [PDF]
Shipin kexue jishu xuebaoMepiquat (Mep) is a food contaminant produced usually during heat processing. It is formed by Maillard reaction with free lysine, reducing sugar and alkylating agent under typical roasting conditions.
HU Chuanqin(胡传芹) +3 more
doaj +1 more source
Hypertension at 5 months postpartum in women with gestational diabetes
Ultrasound in Obstetrics &Gynecology, Volume 68, Issue 2, Page 202-210, August 2026.ABSTRACT Objective Gestational diabetes mellitus (GDM) is associated with future maternal cardiovascular disease, independent of the development of Type‐2 diabetes mellitus. As a major cardiovascular risk factor, we examined the incidence and predictors of hypertension at 5 months postpartum in women with previous GDM.
C. Gómez Fernández +7 more
wiley +1 more source
Functional Ecology, Volume 40, Issue 5, Page 1151-1164, May 2026.Read the free Plain Language Summary for this article on the Journal blog. Abstract Plant phenology is crucial for understanding plant growth and climate feedback. It affects canopy structure, surface albedo, and carbon and water fluxes. While the influence of environmental factors on phenology is well‐documented, the role of plant intrinsic factors ...
Yunpeng Luo +8 more
wiley +1 more source
Advances in Elemene Nanodelivery Systems: From Material Design to Disease Treatment
Rare Metals, Volume 45, Issue 2, February 2026.ABSTRACT Elemene (ELE) is a bioactive sesquiterpenoid extracted from traditional Chinese herbs, demonstrating broad‐spectrum antitumor, anti‐inflammatory, and analgesic properties with significant therapeutic potential. However, its clinical utility is constrained by inherent physicochemical limitations, including volatility and hydrophobicity, which ...
Xiao Wang +9 more
wiley +1 more source
Integrative Conservation, Volume 4, Issue 4, Page 652-664, December 2025.We profiled nutritional and physiological markers in captive sifakas, endangered primates from Madagascar, managed in expansive, non‐native forest enclosures. Variation in many markers reflects freely foraged diets and the energy required to maintain homeostasis under more naturalistic conditions.
Lydia K. Greene +5 more
wiley +1 more source
氢谱磁共振代谢组学在2型糖尿病特征代谢物监测中的应用 [PDF]
, 2018 目的应用氢谱磁共振(~1H-NMR)代谢组学方法研究2型糖尿病(T2DM)患者尿液中小分子代谢物代谢轮廓的变化。方法选择T2DM患者98例及健康对照组82例,利用~1H-NMR方法检测尿液的代谢轮廓,结合偏最小二乘判别分析法的模式识别分析方法,比较两组尿液中小分子代谢物差异。结果尿液的偏最小二乘判别分析法得分图显示与T2DM有关的特征代谢物包括乙酸、乳酸、牛磺酸、乙酰乙酸、葡萄糖、丙氨酸、甲基丙二酸、肌酐、柠檬酸、三甲胺等。结论糖代谢紊乱、氧化应激、氨基酸及脂类代谢异常 ...
张志军, 马红, 董继扬
core
Integrative Conservation, Volume 3, Issue 3, Page 168-182, September 2024.Using long‐term field data, we examined the impact of severe droughts on the health, reproductive success, and behavior of the critically endangered Verreaux's sifaka (Propithecus verreauxi) in Madagascar's seasonally dry tropical forest. Despite reduced availability of high‐quality foods, sifaka exhibited stable body condition and reproductive success,
Carrie C. Veilleux +2 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2002 目的 了解 2型糖尿病 （ⅡDM）患者血脂代谢状况 ,以及血糖控制对血脂代谢的影响 ,为糖尿病患者血脂代谢异常选择治疗时机提供理论依据。方法 对 5 2例ⅡDM患者在血糖控制前后分别进行血糖、血脂检测 ,并与 4 0例健康人的血糖、血脂进行对比分析。结果 ⅡDM患者TCH、TG、LDL C及ApoB升高 ,HDL CApoAI降低 （P
池莲祥 +5 more
doaj