Results 21 to 30 of about 668,371 (153)

谷氨酸棒杆菌戊糖代谢利用研究进展

open access: yes, 2012
戊糖资源高效利用是提高木质纤维原料生物炼制经济效益的关键途径之一,谷氨酸棒杆菌被广泛用于氨基酸以及核苷酸的工业生产,在细胞生长停滞的状态下仍能大量合成氨基酸,对呋喃、糠醛等抑制物也具有良好的耐受性,通过遗传和代谢工程改造,谷氨酸棒杆菌有望成为理想的木质纤维原料催化转化生产菌株。综述了谷氨酸棒杆菌木糖和阿拉伯糖利用工程菌构建的研究进展和策略 ...
叶菁   +6 more
core   +5 more sources

Sensitivity to thyroid hormone and risk of components of metabolic syndrome in a Chinese euthyroid population 中国甲状腺功能正常人群对甲状腺激素的敏感性和代谢综合征组分的风险

open access: yesJournal of Diabetes, Volume 15, Issue 10, Page 900-910, October 2023., 2023
Highlights Mild acquired impaired thyroid hormone sensitivity was widespread among the general populations. Reduced thyroid hormone sensitivity was related with metabolic syndrome and its components. Impaired thyroid hormone sensitivity might affect the distribution of adipose tissue and muscle.
Fang Lv   +6 more
wiley   +1 more source

Beta‐cell function in type 2 diabetes (T2DM): Can it be preserved or enhanced? 2型糖尿病患者的β细胞功能:能被保留或增强吗?

open access: yesJournal of Diabetes, Volume 15, Issue 10, Page 817-837, October 2023., 2023
Highlights Type 2 diabetes mellitus (T2DM) is characterized by progressive loss of beta‐cell function and mass. Numerous mechanisms of beta‐cell failure are involved. Preservation and/or enhancement of beta‐cell function is of great importance in delaying the progression of T2DM and the burden of its complications. Accurate evaluation of the effects of
Laure Sayyed Kassem   +3 more
wiley   +1 more source

Increased glutamate in type 2 diabetes in the Korean population is associated with increased plasminogen levels 韩国2型糖尿病患者谷氨酸升高与纤溶酶原水平升高有关

open access: yesJournal of Diabetes, Volume 15, Issue 9, Page 777-786, September 2023., 2023
Highlights Increased glutamate is associated with the development of diabetes. Glutamate increases plasminogen (PLG) levels through glutamate metabotropic receptor 5 activation with various insulin resistance‐related stresses. Glutamate inhibits the conversion of PLG to plasmin by increasing plasminogen activator inhibitor‐1.
Hyo Jung Lee   +7 more
wiley   +1 more source

Weight loss and metabolic benefits of bariatric surgery in China: A multicenter study 减重手术的减重和代谢获益:一项中国多中心研究

open access: yesJournal of Diabetes, Volume 15, Issue 9, Page 787-798, September 2023., 2023
Highlights Laparoscopic sleeve gastrectomy and laparoscopic Roux‐en‐Y gastric bypass are effective for reducing weight and improving metabolic parameters in Chinese patients with obesity. These interventions resulted in improved glycemic control, as evidenced by decreased glycated hemoglobin levels, reduced insulin resistance, and improved ...
Wenhuan Feng   +6 more
wiley   +1 more source

Mechanisms of bariatric surgery for weight loss and diabetes remission 减重手术减轻体重和缓解糖尿病的机制

open access: yesJournal of Diabetes, Volume 15, Issue 9, Page 736-752, September 2023., 2023
Highlights Controversial changes in intestinal hormones after bariatric surgery (BS) were summarized. The changes of signaling proteins involved in insulin resistance and the newly proposed changes in growth differentiation factor 15, exosomes, and extracellular vesicles after BS were elucidated.
Mengsha Yin   +6 more
wiley   +1 more source

Association between follicle‐stimulating hormone and nonalcoholic fatty liver disease in postmenopausal women with type 2 diabetes mellitus 绝经后2型糖尿病女性中卵泡刺激素与非酒精性脂肪性肝病的相关性

open access: yesJournal of Diabetes, Volume 15, Issue 8, Page 640-648, August 2023., 2023
Highlights In Chinese postmenopausal women with type 2 diabetes mellitus, serum follicle‐stimulating hormone levels were negatively and independently associated with the prevalence of nonalcoholic fatty liver disease. Metabolic conditions, including overweight/obesity, central obesity, hyperuricemia, hypertension, and dyslipidemia did not interact with
Shengjie Ge   +10 more
wiley   +1 more source

Effects of first‐line antidiabetic drugs on the improvement of arterial stiffness: A Bayesian network meta‐analysis 一线降糖药物对动脉硬化改善的影响:贝叶斯网络荟萃分析

open access: yesJournal of Diabetes, Volume 15, Issue 8, Page 685-698, August 2023., 2023
Highlights Vascular complication is one of the most important causes of death in diabetes patients. Arterial stiffness plays a key role in the progress of diabetes vascular complication; therefore, the improvement of arterial stiffness could inhibit the process of atherosclerosis and reduce the burden of diabetes vascular complications This study first
Jincheng Wang   +14 more
wiley   +1 more source

Impact on glucometric variables and quality of life of the advanced hybrid closed‐loop system in pediatric and adolescent type 1 diabetes 高级混合闭环系统对儿童和青少年1型糖尿病患者血糖指标和生活质量的影响

open access: yesJournal of Diabetes, Volume 15, Issue 8, Page 699-708, August 2023., 2023
Highlights This study is the first to evaluate the efficacy of the closed‐loop system MiniMed 780G in children aged 6 to 17 years with type 1 diabetes previously receiving continuous subcutaneous insulin infusion and intermittent continuous glucose monitoring. This shows early results, with improvement in time in range and all hyperglycemia times, from
Alfonso Lendínez‐Jurado   +7 more
wiley   +1 more source

Interventional metabology: A review of bariatric arterial embolization and endovascular denervation for treating metabolic disorders 介入放射学:代谢性疾病治疗手段的新补充

open access: yesJournal of Diabetes, Volume 15, Issue 8, Page 665-673, August 2023., 2023
Highlights Interventional techniques offer novel therapeutic approaches for metabolic disorders such as obesity and type 2 diabetes mellitus, with advantages such as less invasiveness, fewer potential complications, and lower costs. By embolizing specific arteries feeding ghrelin‐producing cells, bariatric arterial embolization not only promotes weight
Zhi Wang   +9 more
wiley   +1 more source

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