[Molecular Mechanism of microRNA-429 Targeting <i>HMOX1</i> to Regulate Invasion, Migration, and Ferroptosis in Lung Adenocarcinoma Cells]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue BanGao X +5 more
europepmc +1 more source
, 2012 细胞机械特性在细胞生命活动中起重要的调控作用,有关细胞机械特性的研究对于破解生命的奥秘具有重要意义.原子力显微镜(AFM)的出现使人们可以在生理环境下对活体状态的细胞机械特性进行测量,在单细胞水平提供了有关细胞机械特性的新认识.利用AFM研究了红细胞和3种不同侵袭程度癌细胞(Burkitt淋巴瘤Raji细胞、皮肤淋巴瘤Hut细胞、慢性粒细胞白血病K562细胞)的形貌结构及机械特性.利用常规AFM探针对红细胞和3种癌细胞的表面形貌进行扫描成像,通过环氧树脂胶水将微球黏附到探针悬臂梁上制成球形探针 ...
肖秀斌 +5 more
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[Angio-associated migratory cell protein is highly expressed in hepatocellular carcinoma and promotes tumor cell invasion and metastasis]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoLi C, Yin G, Cheng X, Jiang Y.
europepmc +1 more source
慢病毒介导shRNA静默CXCR4对Eca109细胞转移特性的影响
, 2010 【目的】 新近研究显示CXCL12/CXCR4通路在食管癌组织中有较高的表达,本研究探讨应用慢病毒介导的RNA干扰技术,有效静默食管癌细胞株Eca109细胞CXCR4的表达,研究CXCL12/CXCR4通路对食管癌Eca109细胞转移能力的影响65377;【方法】 以人CXCR4 mRNA编码序列作为干扰靶点,构建靶向CXCR4的vshRNA表达质粒,另构建不针对任何已知mRNA的阴性对照vshRNA表达质粒,转染相应组别细胞65377;研究分为控制组65380;阴性对照组及静默组65377 ...
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[Anwulignan inhibits malignant phenotypes of gastric cancer cells by antagonizing activation of the JAK1/STAT3 signaling pathway]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoLiu X +9 more
europepmc +1 more source
[Hepatocellular carcinoma-derived lactate-mediated histone H3K18 lactylation modifies S100A2 transcription to promote proliferation, migration, invasion and epithelial-mesenchymal transition of hepatocellular carcinoma cells]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoHuang L, Shao Y, Zhou W, He J.
europepmc +1 more source
[<i>Jianwei Shoutai</i> Pill reduces spontaneous abortion in mice by inhibiting Exo-miR-410-3p uptake and promoting trophoblast epithelial-mesenchymal transition, migration, and invasion]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoXu Z, Chen Z, Xie L, Li X, Qin G, Gao J.
europepmc +1 more source
, 2018 目的 观察用RNA干扰技术沉默人胃癌细胞株MGC-803中钙结合蛋白S100A4的基因,对基质金属蛋白酶2(matrix metalloproteinase 2,MMP-2)和E-钙黏素(E-cadherin)表达变化,探讨S100A4对胃癌细胞侵袭能力的影响及作用机制。方法 采用RNA干扰技术将针对S100A4和非特异性阴性对照序列的si RNA转染至人胃癌MGC-803细胞,利用荧光实时定量RT-PCR和蛋白免疫印迹法(Western Blot)检测S100A4基因和蛋白的表达 ...
张天彪 +5 more
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侵袭性T细胞性非霍奇金淋巴瘤自体造血干细胞 移植后长期随访结果
, 2009 【目的】 评价自体造血干细胞移植(AHSCT)治疗侵袭性T细胞性非霍奇金淋巴瘤(T-NHL)的临床疗效及安全性65377;【方法】 本文回顾性分析1994 ~ 2008年间,我院收治的AHSCT治疗后长期随访的侵袭性T-NHL 36例,初治11例(30.6%),复发11例(30.6%)和难治性病例14例(38.9%)65377;病理类型包括T淋巴母细胞淋巴瘤16例(44.4%)65380;间变大细胞性淋巴瘤8例(22.2%)和外周T非特异型淋巴瘤5例(13.9%)65377; 【结果 ...
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[Phosphatidylinositol glycan anchor biosynthesis class T promotes malignant phenotype of colon cancer through the NF-κB signaling pathway]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoLi B +5 more
europepmc +1 more source