Results 81 to 90 of about 181,012 (129)

[Activation of the CaMKKβ/AMPK/HIF-1α signaling pathway promotes angiogenesis in endometriosis by regulating mitophagy]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Chen Y, Yue B, Wu Q, Mao H, Ji X, Chu C, Chen L, Zhang Y, Li B, Zhang X, Feng P.   +10 more
europepmc   +1 more source

半乳糖凝集素３在血管内皮生长因子Ｃ促宫颈癌转移中的作用

, 2013
【目的】 研究半乳糖凝集素３ （Ｇａｌ－３）在血管内皮生长因子Ｃ（ＶＥＧＦ－Ｃ）促宫颈癌转移中的作用。【方法】 体外培养宫颈癌细胞株ＳｉＨａ细胞，免疫印迹法检测不同浓度的Ｇａｌ－３作用于细胞不同时间，对ＶＥＧＦ－Ｃ受体（ＶＥＧＦＲ３）磷酸化的影响；以ＶＥＧＦ－Ｃ处理ＳｉＨａ细胞１０ ｍｉｎ，免疫共沉淀法观察Ｇａｌ－３与ＶＥＧＦＲ３的蛋白交联变化；转染Ｇａｌ－３ ｓｉＲＮＡ抑制Ｇａｌ－３表达后，采用Ｔｒａｎｓｗｅｌｌ侵袭小室法观察ＶＥＧＦ－Ｃ对ＳｉＨａ细胞侵袭的影响。【结果】 Ｇａｌ－３（１０ μｇ ...

core  

circPRMT5通过靶向miR-98-5p对膀胱癌细胞增殖、迁移侵袭的机制研究

Zhongguo shiyan zhenduanxue
目的 探究circPRMT5通过靶向miR-98-5p对膀胱癌细胞增殖、迁移侵袭的机制研究。方法 qRT-PCR检测永生化正常尿路上皮细胞SV-HUC-1和膀胱癌细胞(T24、J82、HT-1376)中circPRMT5、miR-98-5p和X染色体连锁的凋亡抑制蛋白(XIAP)mRNA相对表达水平。核糖核酸酶(RNase)R和放线菌素D的消化实验鉴定circPRMT5的环状结构。将T24细胞分为si-NC组、si-circPRMT5组、miR-NC组、miR-98-5p组、si-circPRMT5 ...
谢奕彪, 姜良真, 崔小健
doaj  

[Everolimus inhibits malignant phenotype of erdafitinib-resistant bladder cancer cells through the p70S6K/PI3K/MAPK signaling pathway]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Wu H, Jiang Y, Zhang X, Wang S.
europepmc   +1 more source

Snail基因慢病毒载体的构建及其促进结肠癌细胞上皮间质化的研究

, 2012
【目的】 构建Snail基因慢病毒载体,研究Snail基因的表达与结肠癌细胞上皮间质化的关系。【方法】 利用Gateway Technology法构建Snail基因表达质粒和空白对照质粒,行慢病毒包装,成功构建Snail基因慢病毒载体后,在结肠癌细胞系caco2中转染Snail基因质粒及空白载体对照,构建稳转细胞株caco2- Snail和caco2-vc,并在LoVo细胞中瞬时转染上述质粒,对Snail及E-钙黏蛋白(E-cadherin)的表达进行检测,并用划痕 ...

core  

[Multiple components in Astragalus Injection target CCL2/FOS/PPARG/CXCL8 to suppress cervical cancer progression]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Ma Y, Liu Y, Gao N, Huo Y, Chen M, Li J, Liu J, Zhang M, Yan B, Xu N, Zhao J.   +10 more
europepmc   +1 more source

[Overexpression of miR-183-5p enhances malignant phenotype and inhibits ferroptosis of triple-negative breast cancer cells by negatively regulating KLHL24]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Wang K, Hou S, Li Y, Liu Q, Yin C, Li H.
europepmc   +1 more source

[Metformin Inhibits Prostate Cancer Progression via Regulation of the AKT/mTOR Signaling Pathway]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban
Zhang Z, Quan Z, Dai P, Xu K, Yin Z, Chen D, Geng R, Ji X, Wang D, Chen S, Chen L, Liu J.   +11 more
europepmc   +1 more source

[NPLOC4 promotes proliferation, invasion, and migration of hepatocellular carcinoma cells via enhancing Wnt/<b>β-</b>catenin<b>-</b>mediated mitophagy]. [PDF]

Zhong Nan Da Xue Xue Bao Yi Xue Ban
Liang S, Lu Z, Zhu Z, Tang T, Ye K.
europepmc   +1 more source

[<i>circFOXP1</i> Targets miR-4429 to Regulate Proliferation, Migration and Invasion of Nasopharyngeal Carcinoma 6-10B Cells]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban
Zhang Y, Zhang B, Ding Y.
europepmc   +1 more source