Regulation of pyroptosis and ferroptosis by mitophagy in chronic kidney disease. [PDF]
Zhong Nan Da Xue Xue Bao Yi Xue BanHuang Y, Yang L.
europepmc +1 more source
Regulatory effect of NLRP3 on airway inflammatory response and pyroptosis in mice with asthma. [PDF]
Zhongguo Dang Dai Er Ke Za Zhi, 2021 Hui C, Liu X.
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, 2017 炎症小体是一个由多种蛋白形成的功能性复合物，在固有免疫中有重要作用。在细胞炎症反应中，炎症小体可以激活caspase1的活性，进而剪切GSDMD诱发细胞焦亡，同时还能介导细胞因子IL-1β和IL-18的剪切成熟和分泌。细胞焦亡的失调和炎症小体的异常激活都会导致多种自身免疫病。细胞焦亡是新划分的一种程序性细胞死亡方式，最近GSDMD蛋白的发现是细胞焦亡研究的巨大进展之一。GSDMD蛋白在被caspase1/caspase11剪切后，会执行细胞焦亡。但是GSDMD执行细胞焦亡的具体功能机制还未有报道。本文中，
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Nan Fang Yi Ke Da Xue Xue BaoLuo S +6 more
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Nan Fang Yi Ke Da Xue Xue BaoSun Y +6 more
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Zhejiang Da Xue Xue Bao Yi Xue BanHu R +7 more
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[<i>Clostridium perfringens</i> Beta1 toxin induces macrophage pyroptosis and ferroptosis through the purinergic receptor P2X7-Ca<sup>2+</sup> axis]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoZhang S, Ran L, Zeng J, Wang Y.
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Zhongguo Dang Dai Er Ke Za ZhiWen R, Zhang TN, Yang N.
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