Results 61 to 70 of about 1,596 (100)

[Insulin-like growth factor-1 alleviates hepatocyte senescence by regulating intranuclear p53-progerin pathway]. [PDF]

open access: yesZhonghua Gan Zang Bing Za Zhi, 2021
Jiang XK   +11 more
europepmc   +1 more source

糖尿病性骨质疏松与脂肪干细胞成骨分化能力损害机制研究进展

open access: yesZhongshan Daxue xuebao. Yixue kexue ban
糖尿病(DM)患者长期高血糖所致骨质疏松及骨愈合延迟等骨骼并发症已成为显著降低其生活质量的临床难题,其核心机制与脂肪干细胞(ADSCs)成骨分化能力受损密切相关。在骨组织工程中,ADSCs因取材微创、增殖迅速及多向分化能力被视为骨缺损修复的种子细胞,但DM病理环境显著抑制了ADSCs的成骨潜能,进而影响了糖尿病骨病的治疗效率。因此,探索高糖环境下ADSCs成骨能力障碍的深层机制对优化糖尿病骨病的治疗策略具有重要意义。本文系统回顾并总结了高糖环境中ADSCs迁移能力下降、增殖活性降低 ...
韩芳, 田峻
doaj  

[Advances on efficacy and mechanisms of acid fibroblast growth factor for promoting injured tissue repair]. [PDF]

open access: yesZhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
Zhu F   +5 more
europepmc   +1 more source

[Research progress on lactylation modification in pathogenesis of osteoarthritis]. [PDF]

open access: yesZhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
Wu Y   +7 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy