Results 41 to 50 of about 13,468 (164)

Expressions of Cyr61 and WISP-3 in Non-small Cell Lung Cancer and Its Clinical Significance [PDF]

open access: yes, 2010
Background and objective Cysteine-rich protein 61 (Cyr61) plays a role as a tumor suppressor in non-small cell lung cancer (NSCLC). Cyr61 and WISP-3 have a very significant sequence homology, belonging to the same CCN gene family.
Chunwei ZHANG   +3 more
core  

Analysis of the immunomodulatory properties of mycobacterium cell wall fraction on the cytokine production of peripheral blood mononuclear cells of healthy dogs

open access: yesVeterinary Dermatology, Volume 35, Issue 6, Page 595-604, December 2024.
Background – Mycobacterium cell wall fraction (MCWF) is derived from nonpathogenic Mycobacterium phlei and is used as an immunomodulatory compound in clinical practice, yet its mode‐of‐action requires further research. Objective – To evaluate the host response to MCWF in canine peripheral blood mononuclear cells (PBMCs) by using enzyme‐linked ...
Robert Ward   +9 more
wiley   +1 more source

结核分枝杆菌感染的实验室诊断进展

open access: yesZhongguo shiyan zhenduanxue, 2012
结核是当今世界最重要的致病和致死因素之一,据WHO估计,全球已有近20亿人感染结核分枝杆菌(Mycobacterium tuberculosis,MTB),结核患者约2000万人,每年新发患者约800-1 000万人[1]。近年来,由于AIDS的发病率呈上升趋势,而AIDS患者又极易感染结核病,另外近几年结核分枝杆菌隐性感染或亚临床感染持续增多。因此,结核病诊断尤其是快速检测对于及时正确开展抗结核治疗和控制结核病的传播显得尤为重要和迫切。本文就结核病的实验室诊断技术进展综述如下。
蒯守刚, 裴豪
doaj  

Analysis on amide synthase and methyltransferase in biosynthesis of streptovaricin from the strain NRRL 2494 [PDF]

open access: yes, 2015
曲张链菌素(streptovaricin)是由壮观链霉菌(Streptomycesspectabilis)NRRL2494产生的安莎类抗生素,与抗结核药物利福霉素具有相似的化学结构骨架,具有抗菌及免疫抑制等多种生物活性。本论文在对NRRL2494菌株基因组测序的基础上,获得曲张链菌素生物合成基因簇,并通过构建稳定的遗传操作体系,研究其生物合成途径中重要基因的功能,为利用组合生物学手段获得成药性好的曲张链菌素类化合物奠定基础。 本论文首次分析了NRRL2494菌株的基因组全长17.5MB序列 ...
宋姣姣
core  

2014年~2017年某院复治肺结核患者的耐药情况分析 [PDF]

open access: yes, 2018
目的了解我院复治肺结核涂阳患者的耐药谱,为我院预防和治疗结核病提供依据。方法 2014年1月至2017年12月在我院结核病门诊诊断和治疗的涂阳肺结核患者的痰培养结核分枝杆菌,鉴定为结核分枝杆菌的菌株采用比例法,使用6种抗结核药物[异烟肼(H)、利福平(R)、乙胺丁醇(E)、链霉素(S)、氧氟沙星(Ofx)、卡那霉素(Km)]测试耐药性。结果 350例复治肺结核患者的总耐药率为41.71%(146/350),单药耐药(SDR)率为10.25%,多耐药(PDR)率为6.85%,耐多药(MDR)率为24.57%
卢惠萍
core   +1 more source

Fetal lower urinary tract obstruction: international Delphi consensus on management and core outcome set

open access: yesUltrasound in Obstetrics &Gynecology, Volume 64, Issue 5, Page 635-650, November 2024.
ABSTRACT Objectives To reach an international expert consensus on the diagnosis, prognosis and management of fetal lower urinary tract obstruction (LUTO) by means of a Delphi procedure, and to use this to define a core outcome set (COS). Methods A three‐round Delphi procedure was conducted among an international panel of experts in fetal LUTO.
H. J. Mustafa   +90 more
wiley   +1 more source

结核感染T淋巴细胞斑点试验在骨结核病诊断中的临床应用价值

open access: yesZhongguo shiyan zhenduanxue, 2015
结核病是目前全球最常见的传染性疾病之一,结核分枝杆菌相关检查在各种结核病确诊过程中有着举足轻重的作用。传统诊断结核病主要依赖于结核菌涂片,经抗酸染色然后在显微镜下观察,尽管该方法的特异性较强,但是其敏感性较低,且对某些类型结核病如骨结核、中枢神经系统结核来说标本采集难度较大[1-2],从而使得该方法在临床上的应用受到了极大的限制。随着研究的深入,诸多新技术逐步用于结核病的诊断 ...
李建华   +4 more
doaj  

Diagnosis and Treatment of Tracheal or Bronchuotracheal Adenoid Cystic Carcinoma [PDF]

open access: yes, 2010
Background and objective Adenoid cystic carcinoma is primary bronchopulmonary carcinoma with low malignancy, and 43 patients treated in the past 50 years in our hospital were retrospectively studied.
Daping YU   +5 more
core  

Gut microbiota dynamics of adult and sub‐adult sika deer during reintroduction 重引入过程中成年和亚成年梅花鹿肠道微生物的动态变化

open access: yesIntegrative Conservation, Volume 3, Issue 3, Page 257-270, September 2024.
Natural training enclosure design schematic. We selected 12 sika deer including six adults and six sub‐adults. Key considerations in the design of the natural training were to divide the training spatial ground into two parts (30 × 30 m small areas for isolation of new individuals and large areas measuring 200 × 600 m for free walking), and the ...
Wentao Zhang   +10 more
wiley   +1 more source

肺结核患者检测腺苷脱氨酶和高敏C-反应蛋白的临床价值探索

open access: yesZhongguo shiyan zhenduanxue, 2016
肺结核疾病是目前流传最古老的传染性疾病之一,在20世纪80年代中期曾经在全球范围内卷土重来,其主要特点包括结核病控制不规范、耐药结核菌的产生与发展、与艾滋病双重感染等,是人类健康的最大威胁之一[1,2]。中国是世界上22个结核病高负担国家之一,结核病患者数量居世界第二位,肺结核是我国发病、死亡人数最多的重大传染病之一。本文旨在探索肺结核患者检测腺苷脱氨酶和高敏C-反应蛋白的临床价值,结果报道如下。
杨小兵
doaj  

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