Results 41 to 50 of about 19,715 (172)
Rare Metals, Volume 45, Issue 4, April 2026.ABSTRACT Constructing a porous scaffold with the essential features of natural cancellous bone, including structural architecture and biochemical cues, is one of the pivotal factors for effective bone regeneration. In this study, a biomimetic composite porous Gelatin fibrous scaffold (SrHA/Gelatin) incorporating ultralong strontium‐doped hydroxyapatite
Yin‐Chuan Wang +8 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2012 结核是当今世界最重要的致病和致死因素之一,据WHO估计,全球已有近20亿人感染结核分枝杆菌（Mycobacterium tuberculosis,MTB）,结核患者约2000万人,每年新发患者约800-1 000万人[1]。近年来,由于AIDS的发病率呈上升趋势,而AIDS患者又极易感染结核病,另外近几年结核分枝杆菌隐性感染或亚临床感染持续增多。因此,结核病诊断尤其是快速检测对于及时正确开展抗结核治疗和控制结核病的传播显得尤为重要和迫切。本文就结核病的实验室诊断技术进展综述如下。
蒯守刚, 裴豪
doaj
ROS via promoting RIP1 auto-phosphorylation to enhance TNF-induced necrosome formation and subsequent necroptosis [PDF]
, 2015 活性氧（ReactiveOxygenSpecies，ROS）的产生存在于生物体的众多生理病理过程中。大量的实验数据表明，活性氧还参与到了细胞凋亡和程序性坏死的进程里。丁基羟基苯甲醚（Butylatedhydroxyanisole，BHA）是公认的活性氧清除剂，异戊巴比妥（Amytal）是线粒体上电子传递到泛醌的抑制剂，二者都曾被广泛报道，可以抑制或者延缓肿瘤坏死因子（TumorNecroticFactorα，TNF-α）诱导的小鼠成纤维细胞系L929的程序性细胞坏死。然而 ...
张荧荧
core
Rare Metals, Volume 45, Issue 4, April 2026.ABSTRACT A comparative study was performed to elucidate the temperature‐dependent corrosion kinetics and the semiconductor/structural characteristics of the passive film formed on Fe40Ni7Cr17Mo12C13B9Y2 (at%) amorphous alloy coatings. The results indicate that increasing temperature accelerates the corrosion kinetics of the coating.
Yang Lv +12 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2019 目的评价结核感染T细胞斑点试验和结核抗体在肺结核诊断中的应用价值。方法疑似结核住院患者544例(2015.11-2016.11)的痰标本同时使用T-SPOT.TB试剂盒和2种结核抗体金标试剂进行检测,并做抗酸染色涂片及结核分枝杆菌固体培养。结果根据细菌学诊断和临床诊断标准,菌阳肺结核患者210例,菌阴肺结核患者268例,非结核病患者(对照组)66例。T-SPOT.TB检测菌阳的敏感性为84.28%(177/210),菌阴的敏感性为76.87%(206/268),T-SPOT ...
翁绳凤, 邢俊蓬, 郭威
doaj
Structure and function of Streptococcus mutans VicK [PDF]
, 2015 双组分系统TCS包括感受外界刺激信号的组氨酸激酶HK和调控基因转录的应答调节蛋白RR，是许多病原菌应对外界环境变化的主要调节系统。HK能感受如温度、氧浓度、渗透压、pH、菌浓度、抗生素等条件的变化，并对下游的RR进行磷酸化。被磷酸化激活的RR，有60%可以行使转录因子的功能，对相应的基因进行调控，从而使致病菌在压力环境下的生存能力大大增强。 TCS存在于几乎所有的病原菌中，但却未在动物和人类中发现，这使得针对TCS进行药物设计成为一个非常热门的领域。目前，已经开发了很多针对TCS的小分子抑制剂 ...
桑佳燕
core
Rare Metals, Volume 45, Issue 4, April 2026.ABSTRACT This study successfully prepared a high‐palladium (Pd)‐loading (51 wt%) Pd/Al2O3 composite through multiple wet impregnation. The material exhibited excellent hydrogen isotope separation performance, with metal–support interactions endowing it with a higher plateau pressure and lower desorption temperature.
Long Liang +10 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2021 目前结核病仍是全球前十位死因之一[1],死亡率约为16/10万[2]。世界卫生组织(WHO)于2020年10月14日发布《2020年全球结核病报告》。该报告中WHO估算,2019年全球新发患者约996万,其中儿童患者占比12%,女性患者占比32%,男性患者占比56%[2],中国估算有83.3万人新感染结核,在30个结核病高负担国家中,中国估算结核病发病率排第28位,死亡率首次降至末位。同时我国也属高耐药结核病国家[3]。国家"十三五规划"目标指出,到2020年,肺结核发病和死亡人数进一步减少 ...
王岙 +5 more
doaj
How much biotic nativeness matters across human demographic groups
Conservation Biology, Volume 40, Issue 2, April 2026.Abstract Many central concepts of conservation biology—such as nativeness—are structured by ecological and social factors. However, the social consequences of using these concepts to make conservation decisions remain inadequately understood. Some researchers argue that nativeness, rather than acting as an objective proxy for important ecological ...
Harold N. Eyster, Rachelle K. Gould
wiley +1 more source
微量MIC法和罗氏比例法对结核分枝杆菌药敏检测比对及一致性观察分析
Zhongguo shiyan zhenduanxue, 2019 结核病是由于感染结合分枝杆菌而引发的慢性传染病,治疗方法为都药物联合短程化疗,近年来,抗结核药物耐药性结核分支杆菌出现,且钢钒传播,使得控制结核病存在一定难度。当前,全球结核疫情控制的一个最大障碍为结耐药结核病。有关研究数据表明[1],广泛耐药结核病具有传染期常、痰菌转阴慢等特点,其诊断与治疗过程较为复杂,所需治疗费用较高,且具有较多不良反应[2]。本文将以200株结核分枝杆菌菌株为对象,探究微量液体培养基最低抑菌浓度(微量MIC法 ...
王慧 +4 more
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