Survivin基因启动子区-31C/G多态性与散发性 结直肠癌遗传易感性的关系
【目的】 探讨生存素Survivin基因启动子区-31C/G单核苷酸多态性与中国华南地区散发性结直肠癌(CRC)遗传易感性的关系65377; 【方法】 采用聚合酶链反应-限制性片段长度多态性法(PCR-RFLP)检测华南地区711例健康人和702例CRC的Survivin基因-31C/G位点单核苷酸多态性65377;【结果】 结直肠癌患者CC基因型的频率明显高于对照人群(36.35% vs.
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A case of dMMR/MSI-H/TMB-H colon cancer with brain metastasis treated with PD-1 monoclonal antibody. [PDF]
Xiang T, Zhang H, Fang W, Chen W.
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[Recovery of enterogenic sepsis-induced disseminated intravascular coagulation after radical surgery for colon cancer: a case report]. [PDF]
Liu YN, Liang YJ, Zhang J, Ma XC.
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Molecular Mechanism of Apoptosis of Human Colorectal Cancer SW480 Cells Induced by Erianin
毛兰素是名贵中药材石斛的活性化合物之一,研究了其对人结肠癌SW480细胞的增殖抑制作用及其诱导的细胞凋亡分子机制.实验表明,毛兰素能显著抑制结肠癌SW480细胞的增殖,且随着药物浓度与时间增加,抑制率呈明显的剂量时间效应,48 h半数抑制浓度IC50为24.5 nmol/L;毛兰素能显著诱导结肠癌SW480细胞凋亡,并诱导细胞周期阻滞于G2-M期;分子机制研究显示,毛兰素通过下调XIAP、Bcl-xL蛋白表达以及激活Caspase-9、Caspase-7、Caspase ...
苏鹏 +6 more
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[MACC1 knockdown enhances RSL3-induced ferroptosis in human colorectal cancer cells by inhibiting GPX4 expression]. [PDF]
Sun S +7 more
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[Inhibitory Effect of Ginsenoside Rg3 Combined With 5-Fluorouracil on Tumor Angiogenesis and Tumor Growth of Colon Cancer in Mice: An Experimental Study]. [PDF]
Zhao Y +7 more
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[Novel therapeutic strategies for liver metastases driven by the common microenvironment]. [PDF]
Shen LX, Fang WJ, Tong Z.
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[m7G-lncRNAs are potential biomarkers for prognosis and tumor microenvironment in patients with colon cancer]. [PDF]
Chen S, Dong R, Li Y, Wu H, Liu M.
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[Interventional therapeutic strategies for metastatic liver cancer]. [PDF]
Sun XD, Jin L.
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[A transition from targeting immune evasion to a multidisciplinary collaborative treatment framework for "homotherapy for heteropathy" in liver metastases]. [PDF]
Zhang Q, Zhang N, Lu YY.
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