Zhongguo shiyan zhenduanxue, 2012 目的探索舒芬太尼预处理对大鼠心肌缺血再灌注损伤的作用。方法健康雄性SD大白鼠50只,随机分为5组。采用结扎左冠状动脉前降支30分钟再灌注90分钟的方法制备心肌缺血再灌注模型。I/R组为缺血再灌注对比组,IPC组为缺血预处理组,SPC组为舒芬太尼预处理组,将其分为三个亚组,低剂量组（LS组0.20μg/kg）;中剂量组（MS组2.0μg/kg）;高剂量组（HS组5.0μg/kg）。应用Even’s blue-TTC法检测心肌梗死范围,以梗死区心肌重量/缺血区心肌重量（IS/AAR%）来表示。于实验结束时 ...
王嘉, 赵国庆, 高明
doaj
Zhongshan Daxue xuebao. Yixue kexue ban, 1999 目的: 探讨不同流量主动脉转流对腹主动脉暂时性阻断所引起肝、肾和小肠等内脏缺血再灌注损伤的影响。方 法: 实验建立在小猪腹腔动脉开口以上阻断腹主动脉 1 h和同时辅助主动脉转流的模型, 检测在不同再灌注时点肝、肾、小肠 组织及血液中丙二醛( MDA)和超氧化物歧化酶( SOD)的变化,同时检测主要肝肾功能、动脉血气分析。结果: 50%流量组的血 和组织中 MDA 含量和 SOD 的活性在几个再灌注时点与同组的缺血前比较差异有显著性, 且在再灌注 2 h 时 BUN 、pH 和 HCO3 ...
邓美海 区庆嘉 刘 超 刘晓平 彭世军
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Leptin relieves ischemia/reperfusion induced acute kidney injury through inhibiting apoptosis and autophagy. [PDF]
Zhong Nan Da Xue Xue Bao Yi Xue Ban, 2022 Li S +5 more
europepmc +1 more source
[Platelet-rich plasma alleviates myocardial ischemia-reperfusion injury in rats]. [PDF]
Nan Fang Yi Ke Da Xue Xue Bao, 2021 Wang D +7 more
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[Forsythiaside B inhibits cerebral ischemia/reperfusion-induced oxidative stress injury in mice via the AMPK/DAF-16/FOXO3 pathway]. [PDF]
Nan Fang Yi Ke Da Xue Xue Bao, 2023 Chen X +8 more
europepmc +1 more source
Zhongguo shiyan zhenduanxue, 2007 目的研究注射用苦碟子（KDZI）对大鼠心肌缺血再灌注损伤的保护作用及其机制。方法通过大鼠在体结扎冠状动脉前降支30 min后,松扎再灌注120 min制备心肌缺血再灌注损伤模型,计算心肌梗死范围（MIS）,测定血清天门冬氨酸氨基转换酶（AST）、磷酸肌酸激酶（CK）、乳酸脱氢酶（LDH）、超氧物歧化酶（SOD）、谷胱甘肽过氧化物酶（GSH-Px）活性及丙二醛（MDA）含量,血浆内皮素（ET）、血管紧张素Ⅱ（AngⅡ）、前列环素（PGI2）及血栓素A2（TXA2）水平。同时测心肌梗死及非梗死区游离脂肪酸 ...
陈冬梅 +5 more
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Salt-inducible kinase 2 regulates energy metabolism in rats with cerebral ischemia-reperfusion. [PDF]
Zhejiang Da Xue Xue Bao Yi Xue Ban, 2021 Zhang R +5 more
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[Salvianolic acid B promotes mitochondrial homeostasis and improves cardiac function in mice with ischemia-reperfusion injury by inhibiting Sirt1 protein degradation]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoLi S +5 more
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[Down-regulation of SIK2 expression alleviates myocardial ischemia-reperfusion injury in rats by inhibiting autophagy through the mTOR-ULK1 signaling pathway]. [PDF]
Nan Fang Yi Ke Da Xue Xue Bao, 2022 Liu X +5 more
europepmc +1 more source
[Analysis of nerve excitability in the dentate gyrus of the hippocampus in cerebral ischaemia-reperfusion mice]. [PDF]
Sheng Wu Yi Xue Gong Cheng Xue Za ZhiZhu Y, Yu H, Zhao X, Wang C.
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