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中西医结合护理, 2021 Aspiration pneumonia is one of the common complications of patients with ischemic stroke. Understanding the related risk factors of it will help to identify high-risk patients early, and preventive measures are taken early after the occurrence of ...
GUO Qingyuan (郭清源) +3 more
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Zhongshan Daxue xuebao. Yixue kexue ban缺血性脑卒中（CIS）是指因脑部血液循环障碍，缺血、缺氧所致的局限性脑组织的缺血性坏死或软化，其发病率在脑血管病中占据首位。氧气和营养供应的减少会导致神经元的严重丧失，并导致中风患者脑功能的缺陷。开发缺血性脑卒中的治疗方法仍然是临床医学的重要挑战。抗氧化剂N-乙酰半胱氨酸（NAC）是谷胱甘肽前体物质，缺血性脑卒中动物模型及一些临床研究的证据表明，NAC可以有效地保护大脑免受缺血损伤。本文从抗氧化、抑制炎症、保护脑神经和线粒体功能、稳定动脉斑块及溶栓功能等多方面阐述NAC在CIS中的作用机制 ...
杨晨, 万文辉
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Journal of Diabetes, Volume 15, Issue 9, Page 714-723, September 2023., 2023 Highlights There was a U‐shaped relationship between glycemic gap and stroke recurrence during a long‐term follow‐up in a Chinese ischemic stroke registry. Clinical physicians should remain vigilant in the fluctuation of glucose level and use individualized glucose control strategies in patients with ischemic stroke.
Kang Yuan +10 more
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Journal of Diabetes, Volume 15, Issue 4, Page 289-298, April 2023., 2023 Highlights This long‐term longitudinal study demonstrates the association between alcohol consumption and health outcomes in patients with abnormal glucose metabolism including type 2 diabetes mellitus and prediabetes. Occasional drinking (less than once a week) reduces the risk of all‐cause mortality, while heavy alcohol consumption (≥30 g/day for men
Mengzhao Cui +7 more
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Journal of Diabetes, Volume 14, Issue 8, Page 495-513, August 2022., 2022 Highlights During the past 30 years, globally, the disease burden of stroke burden has decreased substantially; however, the disease burden of stroke attributable to high fasting plasma glucose (HFPG) failed to achieve a significant decline. The population‐attributable fraction of HFPG for stroke burden has been increasing across different regions ...
Yang Liu +8 more
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The Anatomical Record, Volume 304, Issue 11, Page 2538-2551, November 2021., 2021 Abstract This study aimed to explore the changes in functional connections between cerebral hemispheres and local brain regions functional activities in patients with acute ischemic stroke (AIS) treated with International Standard Scalp Acupuncture (ISSA).
Huacong Liu +11 more
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, 2023 我国的卒中发病率仍在持续上升，每年新发病例占全球的四分之一。在我国40岁及以上的人群中，缺血性卒中约占所有卒中类型的86.8%。自2019年中国脑血管病临床管理指南发布以来，缺血性卒中急性期再灌注治疗及二级预防抗血小板治疗等领域取得了多项进展。本指南就缺血性卒中急性期评估及诊断、再灌注治疗、抗血小板治疗、其他治疗、常规支持治疗及并发症管理、病因及发病机制的早期评估和诊断、针对病因和发病机制的干预、危险因素管理及长期干预更新推荐意见。 Abstract: The incidence of ...
刘丽萍，周宏宇，段婉莹，霍晓川，聂曦明，刘慧慧，，李子孝，徐蔚海，李淑娟，缪中荣，王拥军，中国卒中学会中国脑血管病临床管理指南撰写工作委员会
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Zhongguo cuzhong zazhi, 2023 出血性卒中主要有脑出血和蛛网膜下腔出血两类。出血性卒中虽然发病率低于缺血性卒中，但往往发病更急，症状更重，且预后更差。更重要的是，目前针对出血性卒中，特别是脑出血的有效干预措施欠缺。因此，出血性卒中指南的更新也受到了很大关注。本文对英国国家卒中临床指南2023版中出血性卒中部分的推荐要点进行解读。 Abstract: Hemorrhagic stroke mainly includes intracerebral hemorrhage and subarachnoid haemorrhage ...
李光硕1，赵性泉1，2
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基于生物信息学途径筛选缺血性脑卒中关键基因及药物预测 [PDF]
, 2021 目的筛选缺血性脑卒中的关键基因及重要信号通路，预测可能对脑卒中有用的药物。方法从GEO数据库下载GSE98319基因芯片数据，该数据包含了假手术组、大脑中动脉梗塞组（MCAO）小鼠的基因芯片检测结果。用R语言的Limma包对数据进行差异表达分析，P<0.05且|log2FC|>0.6的基因为差异表达基因。借助STRING网站构建差异表达基因的蛋白质相互作用网络（PPIN）后由Cytoscape软件进行核心子网络筛选及可视化输出。筛选出核心基因后用实时荧光定量PCR（qRT- PCR ...
王钟兴, 于瑜
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, 2023 《中国脑血管病临床管理指南（第2版）》是中国卒中学会组织专家根据近年来脑血管病领域研究的新进展、获取的新证据，对2019年第1版《中国脑血管病临床管理指南》进行的修订、补充和完善。该版指南涵盖脑血管病的全方位临床管理，包括卒中的组织化管理、高危人群管理、缺血性和出血性卒中以及脑静脉系统血栓形成的临床管理、卒中的康复管理等，旨在为从事卒中防治、护理、康复的相关专业人员和社会工作者，以及政府部门相关管理机构、卫生事业管理人员、医药企业、卫生保健需求方和其他利益相关者提供指导意见。 Abstract ...
谭泽锋，刘丽萍，徐安定，中国卒中学会中国脑血管病临床管理指南撰写工作委员会
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