Results 121 to 130 of about 56,543 (166)

[Role of Receptor Tyrosine Kinase AXL in Cancer Targeted Therapy Drug Resistance]. [PDF]

Zhongguo Fei Ai Za Zhi
Zhan S, Chen P, Lv T, Song Y.
europepmc   +1 more source

[Ethanol promotes oxaliplatin resistance in colorectal cancer by activating the TGF‑β/Smad/P21 signaling axis]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Tan B, Weng N, Zeng W, Gu J, Weng L, Wen H, Xiao H, Zheng K.   +7 more
europepmc   +1 more source

[<i>MUTYH-APEX1</i> Axis Promotes Hepatocellular Carcinoma Progression and Therapeutic Resistance by Regulating Cell Cycle Proteins]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban
Zhou Y, Zhang H, Zhu Y, Jiang P, Feng T, Wu Z, Chen J.   +6 more
europepmc   +1 more source

免疫检查点抑制剂耐药机制研究进展

Zhongshan Daxue xuebao. Yixue kexue ban
免疫检查点抑制剂（ICIs）通过解除对免疫系统的抑制性调控机制，恢复并增强机体的抗肿瘤免疫应答，为肿瘤治疗带来里程碑式飞跃，彻底改变了多种恶性肿瘤的治疗模式，使部分患者的生存期显著延长。然而，临床实践中发现多数患者对ICIs治疗产生原发性耐药（初始治疗无应答）或获得性耐药（疾病得到控制后出现的耐药），极大地限制了其在临床上的广泛应用。ICIs耐药表型的产生可能源于不同的生物学机制，耐药机制复杂，涉及肿瘤细胞自身特性改变、肿瘤微环境重塑以及机体免疫系统状态等多个层面。深入探究ICIs耐药机制 ...
杨彩波, 符立梧
doaj  

[Research progress on poor response, resistance mechanisms, and influencing factors of immunotherapy for hepatocellular carcinoma]. [PDF]

Zhonghua Gan Zang Bing Za Zhi
Huang M, Zhang FN, Gong H, Liu CC, Zhao TT, He N.   +5 more
europepmc   +1 more source

[Tumor-secreted dentin sialophosphoprotein induces oxaliplatin resistance in colorectal cancer through an integrin αvβ3-dependent pathway]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Liu C, Ning Z, Wu J, Liu W, Lin C, Xu J, Zhou R, Zhao L.   +7 more
europepmc   +1 more source

[Molecular Epidemiology and Fluconazole Resistance Mechanisms in <i>Candida tropicalis</i> Isolates From Bloodstream Infections in Sichuan, China]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban
Chen W, Hou J, Peng L, Kang M, Ma Y.
europepmc   +1 more source

[Effects of LINC00641 on the Malignant Progression and Chemotherapy Resistance 
of Non-small Cell Lung Cancer H1299 Cells by Regulating the miR-1306-5p/FGFR3 Axis]. [PDF]

Zhongguo Fei Ai Za Zhi
Wurihan, Du Y, Liu C.
europepmc   +1 more source

[Mechanisms and clinical research progress of mesenchymal stromal cell therapy for steroid-refractory acute graft-versus-host disease]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Wang N, Xu ZL, Liu DH.
europepmc   +1 more source

[<i>Shengmai San</i> improves osimertinib resistance of non-small cell lung cancer cells by regulating the lactate/Wnt/β-catenin/LDHA pathway]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Liang Z, Pan F, Deng L, Mai Z, Ma Y, Shi C, Fu W.   +6 more
europepmc   +1 more source