Results 21 to 30 of about 16,300 (168)

HPV-DNA、TCT联合检测在宫颈癌中的诊断价值

open access: yesZhongguo shiyan zhenduanxue, 2014
目的探讨分析联合检测HPV-DNA和TCT对宫颈癌的诊断价值。方法选择来我院进行妇科检查的女性486例,进行HPV-DNA、TCT检测。结果单项检测HPV-DNA敏感性最高(84.87%),但特异性(52.69%)以及阳性预测值(44.95%)最低;HPV-DNA+TCT联合检测的特异性(81.63%)、阳性预测值(64.61%)和诊断符合率(81.28%)都明显高于两者的单独检测,差异有统计学意义 ...
佟锐, 王纯雁
doaj  

Genomic responses to increased temperature and pollinator selection in Brassica rapa L.

open access: yesNew Phytologist, Volume 250, Issue 2, Page 1231-1247, April 2026.
Summary Rapid environmental change reshapes both abiotic stress and biotic interactions, yet it remains unclear how these combined forces structure plants' genomic adaptation. In particular, the joint influence of temperature and pollinator identity, two ecological axes undergoing simultaneous global shifts, has rarely been quantified at genomic ...
Yanqian Ding, Florian P. Schiestl
wiley   +1 more source

Expression and Clinical Relevance of uPA and ET-1 in Non-small Cell Lung Cancer [PDF]

open access: yes, 2011
Background and objective uPA and ET-1 proteins have been reported to be up-regulated in some of human cancers. The aim of this study is to investigate the alteration and clinical relevance of uPA and ET-1 protein levels in non-small cell lung cancer ...
Boshi WANG   +7 more
core  

Life Stage‐Specific Genetic Diversity and Landscape Characteristics Collectively Influence Genetic Recovery in Pometia pinnata Population 生活史阶段特异的遗传多样性与景观特征对番龙眼种群遗传恢复的协同影响

open access: yesIntegrative Conservation, Volume 5, Issue 1, Page 137-149, March 2026.
Pometia pinnata demonstrated life‐stage‐specific genetic responses to landscape features, with asymmetric gene flow patterns and population recovery following historical bottlenecks, revealing complex topographic and demographic influences on forest genetic structure.
Madhuparna Chatterjee   +5 more
wiley   +1 more source

ANCA和GAB单项与联合检测对溃疡性结肠炎诊断价值的meta分析

open access: yesZhongguo shiyan zhenduanxue, 2018
目的系统评价抗中性粒细胞胞浆抗体(ANCA)、抗小肠杯状细胞抗体(GAB)单项检测,ANCA和GAB联合检测在溃疡性结肠炎(UC)中的临床诊断价值。方法meta分析。检索国内外重要数据库,收集有关于检测ANCA、GAB单项和联合检测在UC患者血清中的阳性表达率及其诊断意义的文献,并按纳入标准与排除标准筛选文献、提取数据,通过随即效应模型合并诊断效应量,绘制综合受试者工作曲线(SROC)来评估ANCA、GAB单项检测和联合检测的诊断效能。结果经过筛选,共纳入符合标准的19篇中英文文献 ...
曾俊祥   +3 more
doaj  

Development and application of CK-MB specific monoclonal antibodies [PDF]

open access: yes, 2017
本研究拟建立肌酸激酶同工酶MB(CK-MB)特异性单克隆抗体(mAb)的研制方法,对抗CK-MB单抗进行评价分类及性质鉴定,并初步建立CK-MB; 定量检测试剂。以CK-MB抗原免疫BALB/c小鼠,利用常规单抗制备技术,使用间接和捕获ELISA差异筛选法筛选单抗。利用肌酸激酶同工酶(CK-; MM/BB/MB)抗原对所制备单抗的抗原识别表位进行鉴定,另通过免疫印迹法及合成CK-MM、CK-BB差异性的线性表位肽鉴定对所制备的单抗进行评; 价分类。使用双抗体夹心ELISA方法筛选检测CK ...
周国梁   +7 more
core   +1 more source

Ultrasound features in early pregnancy for predicting abnormal karyotype in first‐trimester miscarriage

open access: yesUltrasound in Obstetrics &Gynecology, Volume 67, Issue 3, Page 376-384, March 2026.
ABSTRACT Objective To investigate whether combining abnormal morphological features observed on ultrasound in live pregnancies that ended in a first‐trimester miscarriage can predict an abnormal karyotype. Methods This retrospective observational cohort study was conducted at the early‐pregnancy assessment unit at University College London Hospital ...
T. Setty   +5 more
wiley   +1 more source

CA125、CA199和CEA联合检测在卵巢癌诊断中的临床意义

open access: yesZhongguo shiyan zhenduanxue, 2014
目的探讨糖类抗原125(CA125)、糖类抗原199(CA199)和癌胚抗原(CEA)联合检测在卵巢癌诊断中的临床意义。方法选择我院收治的卵巢癌患者80例为研究组,卵巢良性疾病患者80例为对照A组,来院检查的健康者80例为对照B组,采用化学发光法对3组血清中CA125、CA199和CEA含量进行测定。比较3种肿瘤标志物联合检测与单项检测CA125的诊断意义。结果研究组3种肿瘤标志物水平及阳性率均显著高于对照组,且有显著性差异(P0.05)。研究组单项检测及联合检测卵巢癌的阳性率均显著高于两对照组 ...
姜靖, 邓晓阳, 胡晓蕙
doaj  

AFP、GP73及miR-221联合检测对于原发性肝细胞癌的诊断价值

open access: yesZhongguo shiyan zhenduanxue, 2020
目的探讨血清甲胎蛋白(AFP)、高尔基体糖蛋白73(GP73)及miR-221联合检测对于原发性肝细胞癌的诊断价值。方法采用电化学发光法检测50例原发性肝细胞癌(肝癌组)及50例肝炎肝硬化(肝硬化组)患者血清AFP值,同时采用酶联免疫法检测血清GP73、PCR荧光探针法检测miR-221,50例健康者作为对照组。结果 AFP、GP73及miR-221联合检测对原发性肝细胞癌诊断的敏感性分别为66%、64%及74%,特异性分别为78%、80%及70%;三者联合检测对原发性肝细胞癌诊断的敏感性为86 ...
于艳华   +4 more
doaj  

Factors That Influenced Coping With COVID‐19 During the Pandemic in Botswana

open access: yesWorld Medical &Health Policy, Volume 18, Issue 1, March 2026.
ABSTRACT This paper forms part of the broader Global South study, Personal and Family Coping with COVID‐19 in the Global South, which examines psychosocial and behavioral responses to the COVID‐19 pandemic. In Sub‐Saharan Africa, the pandemic posed significant psychological, social, and economic challenges, with important implications for preparedness ...
Magen Mhaka‐Mutepfa   +3 more
wiley   +1 more source

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