Results 21 to 30 of about 16,473 (168)

Evaluating past and future contributions of conservation programs to species recovery

open access: yesConservation Biology, Volume 40, Issue 2, April 2026.
Abstract Impact evaluation of conservation actions is a crucial step in global efforts to curb the biodiversity crisis. Through robust impact evaluation, practitioners can assess the effectiveness of conservation strategies and optimize the use of limited resources.
Rebeca E. Young   +10 more
wiley   +1 more source

HPV-DNA、TCT联合检测在宫颈癌中的诊断价值

open access: yesZhongguo shiyan zhenduanxue, 2014
目的探讨分析联合检测HPV-DNA和TCT对宫颈癌的诊断价值。方法选择来我院进行妇科检查的女性486例,进行HPV-DNA、TCT检测。结果单项检测HPV-DNA敏感性最高(84.87%),但特异性(52.69%)以及阳性预测值(44.95%)最低;HPV-DNA+TCT联合检测的特异性(81.63%)、阳性预测值(64.61%)和诊断符合率(81.28%)都明显高于两者的单独检测,差异有统计学意义 ...
佟锐, 王纯雁
doaj  

Role of RNA helicase DHX32 in the metastasis of hepatocellular carcinoma [PDF]

open access: yes, 2016
肝细胞癌是全球性的高致死率肿瘤之一,血管侵犯和转移是肝细胞癌患者术后易复发及5年生存率较低的重要原因,有效的抗转移策略无疑能给患者带来福音。因此,越来越多的研究致力于探讨肝细胞癌发生侵袭转移的分子机制,并希望通过找到某些关键分子来干预肿瘤的转移。 DHX32是人类RNA螺旋酶的家族成员之一,最早被发现是在急性淋巴细胞白血病中低表达并参与淋巴细胞的分化,但是它的生物学功能尚未明确。我们课题组前期通过差异基因显示技术发现DHX32在结直肠癌中表达上调,功能研究结果显示DHX32与结直肠癌细胞的增殖 ...
胡情
core  

Genomic responses to increased temperature and pollinator selection in Brassica rapa L.

open access: yesNew Phytologist, Volume 250, Issue 2, Page 1231-1247, April 2026.
Summary Rapid environmental change reshapes both abiotic stress and biotic interactions, yet it remains unclear how these combined forces structure plants' genomic adaptation. In particular, the joint influence of temperature and pollinator identity, two ecological axes undergoing simultaneous global shifts, has rarely been quantified at genomic ...
Yanqian Ding, Florian P. Schiestl
wiley   +1 more source

Development and application of CK-MB specific monoclonal antibodies [PDF]

open access: yes, 2017
本研究拟建立肌酸激酶同工酶MB(CK-MB)特异性单克隆抗体(mAb)的研制方法,对抗CK-MB单抗进行评价分类及性质鉴定,并初步建立CK-MB; 定量检测试剂。以CK-MB抗原免疫BALB/c小鼠,利用常规单抗制备技术,使用间接和捕获ELISA差异筛选法筛选单抗。利用肌酸激酶同工酶(CK-; MM/BB/MB)抗原对所制备单抗的抗原识别表位进行鉴定,另通过免疫印迹法及合成CK-MM、CK-BB差异性的线性表位肽鉴定对所制备的单抗进行评; 价分类。使用双抗体夹心ELISA方法筛选检测CK ...
周国梁   +7 more
core   +1 more source

Life Stage‐Specific Genetic Diversity and Landscape Characteristics Collectively Influence Genetic Recovery in Pometia pinnata Population 生活史阶段特异的遗传多样性与景观特征对番龙眼种群遗传恢复的协同影响

open access: yesIntegrative Conservation, Volume 5, Issue 1, Page 137-149, March 2026.
Pometia pinnata demonstrated life‐stage‐specific genetic responses to landscape features, with asymmetric gene flow patterns and population recovery following historical bottlenecks, revealing complex topographic and demographic influences on forest genetic structure.
Madhuparna Chatterjee   +5 more
wiley   +1 more source

ANCA和GAB单项与联合检测对溃疡性结肠炎诊断价值的meta分析

open access: yesZhongguo shiyan zhenduanxue, 2018
目的系统评价抗中性粒细胞胞浆抗体(ANCA)、抗小肠杯状细胞抗体(GAB)单项检测,ANCA和GAB联合检测在溃疡性结肠炎(UC)中的临床诊断价值。方法meta分析。检索国内外重要数据库,收集有关于检测ANCA、GAB单项和联合检测在UC患者血清中的阳性表达率及其诊断意义的文献,并按纳入标准与排除标准筛选文献、提取数据,通过随即效应模型合并诊断效应量,绘制综合受试者工作曲线(SROC)来评估ANCA、GAB单项检测和联合检测的诊断效能。结果经过筛选,共纳入符合标准的19篇中英文文献 ...
曾俊祥   +3 more
doaj  

A Novel Method for Detecting p53 Autoantibodies in Sera of Patients with NSCLC [PDF]

open access: yes, 2009
Background and objective Serum autoantibody detection is useful means for the early diagnosis and prognosis of cancer. So our objective was to synthesize peptide array to analyse p53 autoantibodies in the sera of patients with non small cell lung cancer (
Kai TANG   +4 more
core  

Diagnosis of the severity of diabetic retinopathy by optical coherence tomography angiography combined with fundus fluorescein angiography [PDF]

open access: yes
Objective To explore the diagnostic value of optical coherence tomography angiography(OCTA)combined with fundus fluorescein angiography(FFA)in assessing the severity of diabetic retinopathy.
PENG Jinyan,CHEN Jingxia,YANG Junling,ZOU Xiulan,ZOU Yuping,PENG Lianghong
core   +2 more sources

Ultrasound features in early pregnancy for predicting abnormal karyotype in first‐trimester miscarriage

open access: yesUltrasound in Obstetrics &Gynecology, Volume 67, Issue 3, Page 376-384, March 2026.
ABSTRACT Objective To investigate whether combining abnormal morphological features observed on ultrasound in live pregnancies that ended in a first‐trimester miscarriage can predict an abnormal karyotype. Methods This retrospective observational cohort study was conducted at the early‐pregnancy assessment unit at University College London Hospital ...
T. Setty   +5 more
wiley   +1 more source

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