Results 11 to 20 of about 13,363 (168)

Correlation analysis of IL‐37 gene polymorphisms and susceptibility to chronic HBV infection among Han people in Central China

open access: yesInternational Journal of Immunogenetics, Volume 50, Issue 6, Page 299-305, December 2023., 2023
Abstract Hepatitis B virus (HBV) is responsible for various liver diseases, such as chronic hepatitis B (CHB), liver fibrosis, liver cirrhosis (LC) and hepatocellular carcinoma (HCC), which pose a significant threat to human health. An ineffective immune response to HBV can result in viral chronicity.
Hai Cheng   +3 more
wiley   +1 more source

Increased glutamate in type 2 diabetes in the Korean population is associated with increased plasminogen levels 韩国2型糖尿病患者谷氨酸升高与纤溶酶原水平升高有关

open access: yesJournal of Diabetes, Volume 15, Issue 9, Page 777-786, September 2023., 2023
Highlights Increased glutamate is associated with the development of diabetes. Glutamate increases plasminogen (PLG) levels through glutamate metabotropic receptor 5 activation with various insulin resistance‐related stresses. Glutamate inhibits the conversion of PLG to plasmin by increasing plasminogen activator inhibitor‐1.
Hyo Jung Lee   +7 more
wiley   +1 more source

Association between follicle‐stimulating hormone and nonalcoholic fatty liver disease in postmenopausal women with type 2 diabetes mellitus 绝经后2型糖尿病女性中卵泡刺激素与非酒精性脂肪性肝病的相关性

open access: yesJournal of Diabetes, Volume 15, Issue 8, Page 640-648, August 2023., 2023
Highlights In Chinese postmenopausal women with type 2 diabetes mellitus, serum follicle‐stimulating hormone levels were negatively and independently associated with the prevalence of nonalcoholic fatty liver disease. Metabolic conditions, including overweight/obesity, central obesity, hyperuricemia, hypertension, and dyslipidemia did not interact with
Shengjie Ge   +10 more
wiley   +1 more source

Insights from basic adjunctive examinations of GCK‐MODY, HNF1A‐MODY, and type 2 diabetes: A systemic review and meta‐analysis GCK‐MODY、HNF1A‐MODY和2型糖尿病的基础辅助检查的见解:一项系统回顾和meta分析

open access: yesJournal of Diabetes, Volume 15, Issue 6, Page 519-531, June 2023., 2023
Highlights For distinguishing glucokinase maturity‐onset diabetes of the young (GCK‐MODY) from hepatocyte nuclear factor 1‐α MODY (HNF1A‐MODY), total triglycerides may help during the follow‐up period. In order to discriminate GCK‐MODY from MODY‐like type 2 diabetes, high‐sensitivity C‐reactive protein may be a suitable indicator in the early stage ...
Jing Liu   +3 more
wiley   +1 more source

Developing a prediction model for all‐cause mortality risk among patients with type 2 diabetes mellitus in Shanghai, China 中国上海地区建立的2型糖尿病患者全因死亡风险预测模型

open access: yesJournal of Diabetes, Volume 15, Issue 1, Page 27-35, January 2023., 2023
Highlights This study constructed the first 5‐year all‐cause mortality risk prediction model for patients with type 2 diabetes mellitus in south China. This well‐performing model, using highly accessible predictors collected in routine clinical settings, provides a powerful tool for clinicians to identify high‐risk diabetic patients.
Jiying Qi   +10 more
wiley   +1 more source

Electroacupuncture reduces blood glucose by regulating intestinal flora in type 2 diabetic mice 电针通过调节2型糖尿病小鼠肠道菌群降低血糖

open access: yesJournal of Diabetes, Volume 14, Issue 10, Page 695-710, October 2022., 2022
Highlights Electroacupuncture (EA) regulates the intestinal flora by promoting intestinal motility. EA regulated the intestinal flora to reduce the level of systemic inflammation. EA lowering the blood glucose by the IKKβ/NF‐κB‐JNK‐IRS‐1‐AKT signal pathway.
Jing An   +7 more
wiley   +1 more source

Nonalcoholic fatty liver disease in relation to the remission and progression along the glycemic continuum 非酒精性脂肪性肝病与血糖的缓解和进展

open access: yesJournal of Diabetes, Volume 14, Issue 9, Page 606-619, September 2022., 2022
Highlights To what extent NAFLD is associated with glycemic remission among the general population remains unclear. The study elaborated that presence of NAFLD and fibrosis status decreased the chance of glycemic remission whereas NAFLD improvement mitigated glycemic deterioration, emphasizing joint management to liver‐focused subgroups of diabetes ...
Zhuojun Xin   +15 more
wiley   +1 more source

Targeting the PI3K/Akt signaling pathway in pancreatic β‐cells to enhance their survival and function: An emerging therapeutic strategy for type 1 diabetes 一种新兴的1型糖尿病治疗策略:靶向胰腺β细胞中的PI3K/Akt信号通路以增强其存活和功能

open access: yesJournal of Diabetes, Volume 14, Issue 4, Page 247-260, April 2022., 2022
Highlights Phosphoinositide 3‐kinase (PI3K)/Akt signaling is an emerging promising therapeutic target for diabetes. Modulation of the PI3K/Akt signaling pathway, via protein and peptide‐based biologics, parasite‐derived molecules, plant extracts, or through microRNA interactions, will regulate the processes that determine the function of β‐cells and ...
Inah Camaya   +2 more
wiley   +1 more source

Chinese Medical Entity Recognition Model Based on Character and Word Vector Fusion

open access: yesScientific Programming, Volume 2021, Issue 1, 2021., 2021
The medical information carried in electronic medical records has high clinical research value, and medical named entity recognition is the key to extracting valuable information from large‐scale medical texts. At present, most of the studies on Chinese medical named entity recognition are based on character vector model or word vector model.
Qinghui Zhang   +5 more
wiley   +1 more source

Serum concentrations of IL‐31 in dogs with nonpruritic mast cell tumours or lymphoma

open access: yesVeterinary Dermatology, Volume 31, Issue 6, Page 466-e124, December 2020., 2020
Background The aim of this study was to compare serum interleukin (IL)‐31 concentrations in dogs with lymphoma and mast cell tumours (MCT) without pruritus to those of healthy dogs. Hypothesis/Objectives To determine if IL‐31 plays a role in tumour pathogenesis and if IL‐31 could be a biological marker for disease progression.
Nataliia Ignatenko   +8 more
wiley   +1 more source

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