Results 21 to 30 of about 247,613 (164)

Nonalcoholic fatty liver disease in relation to the remission and progression along the glycemic continuum 非酒精性脂肪性肝病与血糖的缓解和进展

open access: yesJournal of Diabetes, Volume 14, Issue 9, Page 606-619, September 2022., 2022
Highlights To what extent NAFLD is associated with glycemic remission among the general population remains unclear. The study elaborated that presence of NAFLD and fibrosis status decreased the chance of glycemic remission whereas NAFLD improvement mitigated glycemic deterioration, emphasizing joint management to liver‐focused subgroups of diabetes ...
Zhuojun Xin   +15 more
wiley   +1 more source

Targeting the PI3K/Akt signaling pathway in pancreatic β‐cells to enhance their survival and function: An emerging therapeutic strategy for type 1 diabetes 一种新兴的1型糖尿病治疗策略:靶向胰腺β细胞中的PI3K/Akt信号通路以增强其存活和功能

open access: yesJournal of Diabetes, Volume 14, Issue 4, Page 247-260, April 2022., 2022
Highlights Phosphoinositide 3‐kinase (PI3K)/Akt signaling is an emerging promising therapeutic target for diabetes. Modulation of the PI3K/Akt signaling pathway, via protein and peptide‐based biologics, parasite‐derived molecules, plant extracts, or through microRNA interactions, will regulate the processes that determine the function of β‐cells and ...
Inah Camaya   +2 more
wiley   +1 more source

The humanistic care in nursing management of patients with liver disease under the regular epidemic prevention and control (常态化疫情防控下肝病患者的人文关怀与护理管理)

open access: yes中西医结合护理, 2022
Objective To investigate the effect of humanistic care in nursing management of patients with liver disease under the under the regular epidemic prevention and control of COVID-19.
LIU Xuejiao (刘雪姣)   +5 more
doaj   +1 more source

Chinese Medical Entity Recognition Model Based on Character and Word Vector Fusion

open access: yesScientific Programming, Volume 2021, Issue 1, 2021., 2021
The medical information carried in electronic medical records has high clinical research value, and medical named entity recognition is the key to extracting valuable information from large‐scale medical texts. At present, most of the studies on Chinese medical named entity recognition are based on character vector model or word vector model.
Qinghui Zhang   +5 more
wiley   +1 more source

Serum concentrations of IL‐31 in dogs with nonpruritic mast cell tumours or lymphoma

open access: yesVeterinary Dermatology, Volume 31, Issue 6, Page 466-e124, December 2020., 2020
Background The aim of this study was to compare serum interleukin (IL)‐31 concentrations in dogs with lymphoma and mast cell tumours (MCT) without pruritus to those of healthy dogs. Hypothesis/Objectives To determine if IL‐31 plays a role in tumour pathogenesis and if IL‐31 could be a biological marker for disease progression.
Nataliia Ignatenko   +8 more
wiley   +1 more source

Commitment to academic impartiality and independence to promote the healthy development of hepatology in China: joint comments from Chinese Journal of Hepatology, Journal of Clinical Hepatology, and Chinese Hepatology

open access: yes, 2017
近年来,随着基础研究、药物开发与临床研究的进展,有关肝脏疾病诊断和治疗的新理论、新药物、新技术和新方法不断涌现,临床治疗观念也不断更新.目前通过3到6个月的全口服抗病毒治疗,能够使95%以上的慢性丙型肝炎达到临床治愈.长期有效的抗乙型肝炎病毒治疗能够改善肝脏炎症坏死、逆转肝纤维化和早期肝硬化,减少肝硬化失代偿及肝细胞癌的发生,而且针对乙型肝炎病毒感染、复制过程及机体免疫应答诸多环节的新药研发也取得重要进展,慢性乙型肝炎的治疗目标逐步提高到追求临床治愈或功能性治愈阶段.中国科学引文数据库(CSCD)13 ...
贾继东   +4 more
core   +1 more source

Nursing management of secondary toxic epidermal necrolysis after PD-1 monoclonal antibody treatment in a patient with primary liver cancer (原发性肝癌PD-1单抗治疗后继发中毒性表皮坏死松解症1例护理体会)

open access: yes中西医结合护理
This article summarized the nursing experience of a patient with skin lesion caused by toxic epidermal necrolysis (TEN) after treatment of primary liver cancer with PD-1 antibot-targeted drugs. The nursing issues were as follows: Comprehensive evaluation
GAO Chensi (高晨思)   +3 more
doaj   +1 more source

Opportunities and challenges for the treatment of chronic hepatitis C

open access: yes, 2017
慢性丙型肝炎是危害全人类的疾病,2016年世界卫生组织提出首个全球病毒性肝炎战略,提出“到2030年,消除作为公共卫生威胁的病毒性肝炎”的目标,在慢性丙型肝炎治疗方面存在着机遇与挑战.Chronic hepatitis C is a great threat to human health.The World Health Organization presented Draft global health sector strategies in 2016,the goal of the draft ...
罗碧芬, 魏来
core   +1 more source

De novo autoimmune hepatitis after liver transplantation

open access: yes, 2016
肝移植患者移植后可出现新发自身免疫性肝炎(de novo autoimmune hepatitis,de novo AIH),该病在肝移植人群中发病率为1.7% ~ 6.6%,多见于有丙型肝炎病毒(HCV)感染、胆道闭锁、胆汁淤积性肝病等肝脏基础疾病的患者,移植与发病间隔在3个月至16年间,多数为移植后1年以上发病,可见于任何年龄段,儿童移植患者中女性多于男性,成人无明显性别差异,主要表现为以转氨酶升高为主、伴或不伴黄疸的肝脏生物化学指标异常、免疫球蛋白IgG升高、多种自身抗体阳性 ...
罗碧芬, 魏来
core   +1 more source

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