Results 21 to 30 of about 13,363 (168)
The effects of Tao-Hong-Si-Wu on hepatic necroinflammatory activity and fibrosis in murine model of chronic liver disease [PDF]
, 2016 背景：桃红四物汤原名加味四物汤，载于《医垒元戎》，录自《玉机微义》，是在四物汤的基础上加桃仁、红花而成，是活血养血之代表方。桃红四物汤在临床上应用广泛，诸多研究表明桃红四物汤对多种慢性肝病有一定的治疗作用。慢性肝损伤伴肝纤维化发展过程中存在明显的病理性血管生成与重构，阻碍了肝纤维化的逆转与恢复。通过桃红四物汤对病理性血管生成作用的研究，发现部分活血化瘀中药具有抑制病理性血管生成的作用，抗病理性血管生成可能是活血化瘀药的现代药理作用之一 ...
史萌萌
core
Animal Models and Experimental Medicine, Volume 8, Issue 8, Page 1387-1399, August 2025.Post‐stroke depression (PSD) animal model of traditional Chinese medicine (TCM) combined with disease and syndrome often uses western medicine surgery (including: middle cerebral artery embolization to construct cerebral ischemia, or brain injection of collagenase to construct cerebral hemorrhage) combined with other methods (including: isolation ...
Jielin Wang +4 more
wiley +1 more source
Optimazation Dosage Study of the Combination of Chlorogenic and Geniposide on Non-alcoholic Fatty Liver Disease [PDF]
, 2015 目的：本研究通过运用数学模型均匀设计法，观察中药有效成分绿原酸、栀子苷配伍使用对高脂饮食诱导非酒精性脂肪性肝病（NAFLD）大鼠模型所产生的药理效应。并从多角度指标分析绿原酸、栀子苷对NAFLD脂质代谢紊乱、肝脏炎症损伤病理状态的影响，筛选出绿原酸-栀子苷组合抗NAFLD的最优剂量配比，探索中药复方治疗NAFLD的药效基础。 方法：1、均匀设计筛选实验：55只雄性Wistar大鼠，随机分为正常组、造模组。正常组普通饲料喂养，造模组采用改良高脂饲料饮食8周诱导NAFLD大鼠模型 ...
赵逍
core
Combating infections under siege: Healthcare challenges amidst the military assault in Gaza
World Medical &Health Policy, Volume 17, Issue 1, Page 188-213, March 2025.Abstract The ongoing Israeli military assault on Gaza has caused a devastating collapse of healthcare infrastructure, resulting in an unprecedented surge in infectious diseases. The destruction of sanitation systems, restrictions on medical supplies, and displacement of civilians have created an environment conducive to the rapid spread of waterborne ...
Bilal Irfan +24 more
wiley +1 more source
The role of C-terminal region of Hepatitis B virus x protein on virus replication and cell death [PDF]
, 2016 在全球范围内，肝细胞癌（HCC）是临床上最常见的恶性肿瘤之一。乙型肝炎病毒（HBV）的持续感染是引起HCC的高危因素。乙型肝炎病毒（HBV）X蛋白（HBx）对于HBV的复制和HBV相关肝癌的发生发展起着重要的作用。本研究从HBV相关肝癌患者的癌、癌旁组织标本和血清标本出发，发现HBV相关肝癌组织的低复制性与HBx羧基端的截短突变有相关性。先前也有研究表明HBx羧基端截短突变体对于HBV的复制水平又不同程度的影响，但是所涉及的亚细胞结构靶点及参与的作用机制尚未阐明 ...
林碧芸
core
Evidence-Based Complementary and Alternative Medicine, Volume 2019, Issue 1, 2019., 2019 A survey study was conducted in Korean medicine doctors who provide nonsurgical integrative treatment for cervical disc herniation (CDH) at spine‐specialty hospitals to assess usual treatment practices, diagnosis and treatment methods, and related adverse events for CDH.
Hee Seung Choi +7 more
wiley +1 more source
Asparagus Oligosaccharide’s Purification and Protection of Acute Alcoholic Liver Injury in Kunming Mice [PDF]
, 2015 寡糖具有抗病毒、抗肿瘤、抗氧化、免疫调节等生物活性，是一种高活性物质，在医药和功能性食品领域显示了巨大的应用前景。与其它来源于植物、几丁质的寡糖相比，目前来源于海藻的寡糖尚未得到大规模开发。本研究前期工作中建立了利用微生物与龙须菜（Gracikarialemaneifarmis）共培养，一步法获得寡糖的方法，简化了生产步骤，降低了成本，并开展了龙须菜寡糖的各项活性研究与开发。本文研究了龙须菜寡糖的纯化方法，并研究其在动物生长、急性酒精肝损伤保护等方面的生理活性。 首先对龙须菜寡糖的纯化制备进行研究 ...
刘海凤
core
9.糖尿病患者におけるグラム陰性桿菌敗血症の2症例(第585回千葉医学会例会・第1内科教室同門会例会) [PDF]
, 2016 Offline computation cost Vs. Performance (inaccurate case).
Adrien Couëtoux (2837570) +3 more
core +3 more sources