Mechanism of Action of Lonicera caerulea Berry Polyphenols in Regulating Intestinal Microecology in Immunosuppressive Mice [PDF]
, 2023 Objective: In order to explore the effects of Lonicera caerulea berry polyphenols (LCBP) on immunity and intestinal flora in immunosuppressive mice. Methods: Thirty-two mice were randomly divided into a blank control group, a model group, a low-dose LCBP
ZHANG Lingyu, PAN Lijia, HOU Suxin, JIANG Shan, YANG Mei, CAO Jiazhen, XU Xiaohong, ZHANG Nan
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野生动物学报, 2023 圈养是濒危野生动物重引入的重要措施之一，为了阐明圈养与野生、散放与圈养条件下鸟类肠道菌群的差异，在Web of Science和CNKI数据库中检索已发表的中英文文献，提取肠道微生物群落数据并使用R（Meta）进行分析。结果表明：圈养与野生相比，鸟类肠道厚壁菌门（Firmicutes）的丰度显著增加，拟杆菌门（Bacteroidetes）和绿弯菌门（Chloroflexi）的丰度显著下降，梭菌属（Clostridium）、拟杆菌属（Bacteroides）和双歧杆菌属（Bifidobacterium ...
王焕, 伍一宁, 邹红菲, 王贺
doaj
Zhongguo cuzhong zazhi, 2023 脑小血管病（cerebral small vessel disease，CSVD）发病率高，病因复杂，精确诊断、分类和随访较为困难。目前，CSVD基因组学已发现超过50个独立遗传位点与CSVD发病风险相关，涉及细胞外基质组成、髓鞘形成、膜转运等病理生理机制，且与临床表现相关。转录组学发现多种微小RNA在CSVD痴呆患者和健康对照中差异性表达；蛋白组学研究异质性较大，提示需选用蛋白质标志物的特定组合才可能有助于CSVD的诊断和分型；宿主-微生物组学研究提示CSVD存在肠道-免疫-脑轴的致病机制 ...
陈悦薇, 徐群
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Probiotics in Alleviating Hyperuricemia: Research Status, Mechanism of Action and Challenges [PDF]
Hyperuricemia (HUA) is a chronic metabolic disease, characterized by excessive uric acid in the blood, caused by purine metabolism disorders. Studies show that conventional clinical treatment methods have certain limitations, while probiotics have the ...
Jiayue TANG +5 more
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Fecal Microbiota Transplantation Induces HBeAg Clearance in Patients with Chronic Hepatitis B with Persistent Positive HBeAg [PDF]
, 2017 背景和目的：慢性乙型肝炎（ChronichepatitisB，CHB）在世界范围内流行，且经过长时程口服抗病毒治疗后仅有少数患者能达到停药标准。粪菌移植（FecalmicrobiotaTransplantation，FMT）已被证明可以诱导缓解多种临床疾病，包括艰难梭菌相关性结肠炎。在本研究中，我们探索了粪菌移植对长期核苷/酸类似物（nucleos(t)ideanalogues，NAs）治疗后HBeAg仍未实现血清学阴转的CHB患者的治疗价值。 实验方法：在该开放性、单盲 ...
任艳丹
core
Application potential of grain and oil processing by-products in research of microbial-oriented food [PDF]
, 2019 Hundreds of millions of bacteria adhere to human intestinal epithelium,which are the participants of human health and physiological functions,and also an important target covered by the concept of comprehensive health.So far,the supplementation of ...
CHEN Hong-juan +8 more
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Advances in the Study of Natural Product Polysaccharides for the Relief of Depression and Their Mechanisms [PDF]
, 2023 Depression, as a common mental disorder, is often alleviated and treated with antipsychotic drugs in clinical practice. However, long-term use of such drugs can lead to serious sequelae such as drowsiness, nausea and memory loss in patients.
Yuhe BAI
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共轭亚油酸降脂及分子机理研究进展Progress in fat reduction of conjugated linoleic acid and its molecular mechanism
Zhongguo youzhi, 2022 共轭亚油酸是一类具有两个共轭双键的十八碳多不饱和脂肪酸混合物的总称，具有确切的减肥降脂活性与可验证的临床安全性，使其成为国际减肥市场的宠儿。简要回顾了共轭亚油酸减肥降脂的研究成果，并从调控能量代谢、脂代谢、骨骼肌代谢和糖代谢，介导脂肪细胞的分化与凋亡以及调节肠道微生物群6个方面总结了共轭亚油酸减肥降脂的作用机制，同时对其存在问题及发展机会做了分析与讨论。共轭亚油酸作为减肥降脂的天然产物，具有更大、更广阔的发展潜力。 Conjugated linoleic acid, a mixture of ...
李海玲1，张思晨1，赵志敏1，2，何国瑞3，杨得坡1，2 LI Hailing1, ZHANG Sichen1, ZHAO Zhimin1,2, HE Guorui3, YANG Depo1,2
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Effect of vitamin C on intestinal flora disorders in Cr(VI)-contaminated mice [PDF]
BackgroundHexavalent chromium [Cr(VI)] exposure can cause structural disruption of intestinal flora and functional impairment. Vitamin C (VC) is one of the essential micronutrients, which plays an important role in promoting the growth of intestinal ...
Chen LIU +9 more
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