Results 21 to 30 of about 2,196 (154)
Effect of rhubarb on gut microbiota-host co-metabolism in rats [PDF]
, 2023 Objective·To study the effect of rhubarb administration on the balance between intestinal flora and the body.Methods·Wistar rats were randomly divided into 4 groups (n=8), which were given extractions of rhubarb 0.1 g/kg (low dose group), 2.5 g/kg ...
GAO Yu +4 more
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The pathogenesis of irritable bowel syndrome (IBS) is still unclear. It may be associated with various factors. The patients suffered from IBS have intestinal flora ecological imbalance.
Chi, Zhao-chun
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应用Illumina MiSeq测序技术对腹泻北平顶猴肠道菌群的分析
野生动物学报, 2021 为探寻可能导致北平顶猴（Macaca leonina）腹泻的菌群及其变化规律，分别采集6只健康和6只腹泻北平顶猴的新鲜粪便，应用Illumina MiSeq高通量测序技术测定其肠道菌群的结构以及腹泻过程中肠道菌群的动态变化。结果表明：健康组肠道菌群的Shannon指数（P=0015）、Chao 1指数（P=0014）、ACE指数（P=0032）较腹泻组高。在门水平上，腹泻组肠道中拟杆菌门（Bacteroidetes）、变形菌门（Proteobacteria）和未鉴定细菌（unidentified ...
金洁 1 +5 more
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皂术茵陈方治疗非酒精性脂肪性肝炎的临床观察及其对肠道菌群的影响 [PDF]
, 2018 目的评价皂术茵陈方调节肠道菌群治疗非酒精性脂肪性肝炎(NASH)的临床疗效及其作用机制。方法选取福建中医药大学附属厦门市中医院肝病中心门诊就诊的NASH患者80例,采用随机数字表法分为治疗组(40例)和对照组(40例)。治疗组予中药皂术茵陈方治疗,对照组予以枯草杆菌二联活菌肠溶胶囊治疗,两组疗程均为12周。评价治疗前后两组患者的症状、体征积分以及血清ALT、AST活性;检测两组患者血清内毒素水平以及肠道菌群变化。结果治疗12周后,治疗组的临床总有效率达87.5%(35/40),较之对照组的65%(26 ...
唐金模 +7 more
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Integrative Conservation, Volume 3, Issue 3, Page 257-270, September 2024.Natural training enclosure design schematic. We selected 12 sika deer including six adults and six sub‐adults. Key considerations in the design of the natural training were to divide the training spatial ground into two parts (30 × 30 m small areas for isolation of new individuals and large areas measuring 200 × 600 m for free walking), and the ...
Wentao Zhang +10 more
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The Research progress on the effect of gut microbiota changes on postoperative renal transplantation patients [PDF]
A series of complications such as diarrhea, infection and rejection are easy to occur after renal transplantation, which seriously affects the survival rate of the grafts and the survival rate of patients after renal transplantation. With the development
CHEN Huaizhou +8 more
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Veterinary Dermatology, Volume 35, Issue 4, Page 375-385, August 2024.Background – Perianal fistulas are painful ulcers or sinus tracts that disproportionately affect German shepherd dogs and are proposed as a spontaneous animal model of fistulising Crohn's disease. Objectives – To characterise the rectal and cutaneous microbiota in German shepherd dogs with perianal fistulas and to investigate longitudinal shifts with ...
Christine L. Cain +6 more
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Fecal Microbiota Transplantation Induces HBeAg Clearance in Patients with Chronic Hepatitis B with Persistent Positive HBeAg [PDF]
, 2017 背景和目的：慢性乙型肝炎（ChronichepatitisB，CHB）在世界范围内流行，且经过长时程口服抗病毒治疗后仅有少数患者能达到停药标准。粪菌移植（FecalmicrobiotaTransplantation，FMT）已被证明可以诱导缓解多种临床疾病，包括艰难梭菌相关性结肠炎。在本研究中，我们探索了粪菌移植对长期核苷/酸类似物（nucleos(t)ideanalogues，NAs）治疗后HBeAg仍未实现血清学阴转的CHB患者的治疗价值。 实验方法：在该开放性、单盲 ...
任艳丹
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LMP-027 Anti-Clostridium difficile activity, drug combination synergetic/additive effect, and tolerant mutant screening and characterization [PDF]
, 2017 抗菌药物是对抗细菌感染的有力武器，自第一种抗生素青霉素被发现并应用于临床以来，人类已经开发出多种抗菌药物，然而由于抗菌药物的不合理使用，细菌耐药问题日益严峻，多重耐药菌不断出现，对人类健康构成严重威胁。这需要研发新型抗菌药物用于治疗多耐药细菌引起的感染；然而传统抗菌药物开发耗时长、成本高、风险大，医药公司对此并不热衷，新型抗菌药物上市越来越少。老药新用是抗菌药物开发的新思路，这些药物已经用于临床或正在进行临床试验，安全性评价资料齐全，这大大减少药物开发的成本和风险。过去几十年间 ...
刘俊坚
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Application of Gut Microbiota Research Models and Omics Techniques to the Risk Assessment of Chemical Hazards in Foods [PDF]
Chemical hazards in foods have become a global public health challenge with the widespread use of chemicals in food processing. Currently, the effects of chemical exposure on human health are usually assessed by relying on complex and invasive assays for
ZHAI Qixiao, YIN Pingping, WANG Shumin
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