Effect to Intestinal Microbiota Regulation and Laxative Function to Lactobacillus paracasei [PDF]
The effects of five strains of Lactobacillus paracasei from Tibet on constipation and gut microbiota of mice were studied. One hundred and sixty male Kunming mice were randomly divided into two groups: A and B.
Jing YANG +8 more
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Fecal Microbiota Transplantation Induces HBeAg Clearance in Patients with Chronic Hepatitis B with Persistent Positive HBeAg [PDF]
, 2017 背景和目的：慢性乙型肝炎（ChronichepatitisB，CHB）在世界范围内流行，且经过长时程口服抗病毒治疗后仅有少数患者能达到停药标准。粪菌移植（FecalmicrobiotaTransplantation，FMT）已被证明可以诱导缓解多种临床疾病，包括艰难梭菌相关性结肠炎。在本研究中，我们探索了粪菌移植对长期核苷/酸类似物（nucleos(t)ideanalogues，NAs）治疗后HBeAg仍未实现血清学阴转的CHB患者的治疗价值。 实验方法：在该开放性、单盲 ...
任艳丹
core
Research progress in the relationship between gut microbia and its metabolites and gestational diabetes mellitus [PDF]
, 2023 The global incidence of gestational diabetes mellitus (GDM) continues to rise in recent years. Research has shown that GDM can increase the risk of adverse pregnancy outcomes in pregnant women and lead to malignant intergenerational circulation.
FANG Zichen +5 more
core +1 more source
LMP-027 Anti-Clostridium difficile activity, drug combination synergetic/additive effect, and tolerant mutant screening and characterization [PDF]
, 2017 抗菌药物是对抗细菌感染的有力武器，自第一种抗生素青霉素被发现并应用于临床以来，人类已经开发出多种抗菌药物，然而由于抗菌药物的不合理使用，细菌耐药问题日益严峻，多重耐药菌不断出现，对人类健康构成严重威胁。这需要研发新型抗菌药物用于治疗多耐药细菌引起的感染；然而传统抗菌药物开发耗时长、成本高、风险大，医药公司对此并不热衷，新型抗菌药物上市越来越少。老药新用是抗菌药物开发的新思路，这些药物已经用于临床或正在进行临床试验，安全性评价资料齐全，这大大减少药物开发的成本和风险。过去几十年间 ...
刘俊坚
core
Analysis of Gut Flora in a Mouse Model of Esophageal Squamous Cell Carcinoma in Situ [PDF]
, 2022 BackgroundWith the application and development of high-throughput sequencing-based approaches for gut flora analysis, increasing studies have confirmed that gut flora is closely related to the development of various cancers.
ZHANG Yushuang, YU Fuyang, WU Zhongbing, WANG Yiran, LI Jing
core +1 more source
野生动物学报, 2021 在圈养条件下，为了探知孟加拉白虎（Panthera tigris tigris）的肠道菌群结构以及不同年龄孟加拉白虎的肠道菌群差异，对亚成年和成年孟加拉白虎的粪便菌群进行高通量测序分析。结果表明：在2组白虎的肠道菌群中，放线菌门（Actinobacteria）和厚壁菌门（Firmicutes）最为优势，比例达80%以上；柯林斯菌属（Collinsella）比例最高，平均含量为438%，梭杆菌属（Fusobacterium）、布劳特氏菌属（Blautia）和瘤胃球菌类群（Ruminococcus ...
苏凯#雷英#金修哲李金邦
doaj
Advances in Understanding the Role Mechanism of Dietary Fiber in Mitigating Colitis [PDF]
Colitis is an inflammatory intestinal disease that lasts for a long time, has an unknown cause, and occurs repeatedly. It is usually accompanied by symptoms such as intestinal cell damage, intestinal immunity, and abnormal intestinal flora.
Daling HE +5 more
core +1 more source
Molecular diversity of the intestinal bacterial flora in small abalone, Haliotis diversicolor [PDF]
, 2010 杂色鲍是我国南方沿海海水养殖的重要经济贝类。肠道菌群在宿主生长发 育、新陈代谢等方面起到重要作用。通过开展杂色鲍肠道菌群多样性的研究，旨 在理解肠道菌群与杂色鲍之间相互关系，包括消化食物、病理发生等，对探讨微 生物与海洋无脊椎动物相互关系具有重要意义。 本文通过微生物分离培养鉴定与不依赖培养的微生物分子生态学方法对不 同养殖环境的杂色鲍肠道菌群的多样性进行研究。从两个养鲍场（江口、大嶝） 杂色鲍肠道内共分离到35株细菌，经16SrRNAgene分子鉴定分属于9个属， 分别为Vibrio ...
黄兆斌
core
Regulation of Yeast Extract-Curcumin on Intestinal Flora in Mice with Acute Alcoholic Liver Injury [PDF]
Objective: This study aimed to investigate the protective effect and mechanism of yeast extract and curcumin-yeast extract on acute alcoholic liver injury in mice.
Haili YU +4 more
core +1 more source
Zhongguo shiyan zhenduanxue, 2017 1肠道菌群与2型糖尿病人体胃肠道中存在着大量的正常菌群,其肠道内微生物主要由厚壁菌门、拟杆菌门、放线菌门、变形菌门以及疣微球菌门组成,而厚壁菌门及拟杆菌门占优势,某些病毒及真核生物也同时存在于肠道内[3]。肠道菌群和肥胖症的发生有很大的关系,其与2型糖尿病的关系亦是如此,有学者发现,改变肠道菌群构成 ...
宋丹丹, 刘煜
doaj