Results 21 to 30 of about 2,007 (105)

基于“心与小肠相表里”探讨阿尔茨海默病小鼠全肠道菌群移植对回肠肠道微环境的影响

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2023
目的在“心与小肠相表里”中医理论指导下,探讨阿尔茨海默病(AD)模型小鼠全肠道菌群移植,是否对正常小鼠回肠肠道微环境的影响更显著。方法将14只6月龄无特定病原体的雄性APP/PS1双转基因AD模型小鼠的全肠道菌群,移植至6只混合抗生素处理过的同月龄同背景正常C57BL/6J小鼠肠道内,移植14 d后再定殖14 d,观察小鼠回肠和结肠组织病理变化,并采用16S核糖体RNA(16S rRNA)基因测序技术分析小鼠回肠和结肠菌群。结果AD小鼠全肠道菌群移植到正常小鼠后 ...
熊伟   +7 more
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Effects of regulating intestinal microbiota on anxiety symptoms: A systematic review

open access: yesGeneral Psychiatry, Volume 32, Issue 2, July 2019., 2019
Background Anxiety symptoms are common in mental diseases and a variety of physical disorders, especially in disorders related to stress. More and more basic studies have indicated that gut microbiota can regulate brain function through the gut‐brain axis, and dysbiosis of intestinal microbiota was related to anxiety.
Beibei Yang   +3 more
wiley   +1 more source

圈养梅花鹿肠道菌群组成的性别差异

open access: yes野生动物学报, 2023
为探究圈养梅花鹿(Cervus nippon)肠道菌群的结构、多样性以及肠道菌群组成的性别差异,利用Illumina MiSeq高通量测序平台对10只圈养健康梅花鹿粪便中的细菌16S rRNA V3—V4区扩增子进行PCR扩增,采用生物信息学手段以性别作为分组因素,分析雄、雌圈养梅花鹿肠道菌群的结构、多样性和差异物种。结果显示:在门水平上,圈养梅花鹿肠道菌群的优势菌门为厚壁菌门(Firmicutes;雄性61.69%,雌性58.23%)和拟杆菌门(Bacteroidetes;雄性27.40%,雌性31 ...
史倍宁   +7 more
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慢性萎缩性胃炎伴肠上皮化生患者体质类型与肠道菌群相关性研究

open access: yesZhongguo shiyan zhenduanxue, 2023
目的 探讨慢性萎缩性胃炎伴肠上皮化生患者体质类型与肠道菌群相关性。方法 以2021年1~8月期间川北医学院附属医院收治的144例慢性萎缩性胃炎伴肠上皮化生患者为研究对象,均于确诊时行肠道菌群检测及体质类型诊断,根据体质类型(病态体质、和平体质)分为病态体质组和和平体质组。观察病态体质组和和平体质组的肠道菌群(各菌属类群相对丰度、各菌门类群相对丰度、菌群多样性(Chao1指数、Shannon指数、Sobs指数)差异,并采用Spearman秩相关法分析体质类型(是否病态体质)与肠道菌群指标的相关性。结果 ...
杨阳, 刘浩, 刘洁
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应用Illumina MiSeq测序技术对腹泻北平顶猴肠道菌群的分析

open access: yes野生动物学报, 2021
为探寻可能导致北平顶猴(Macaca leonina)腹泻的菌群及其变化规律,分别采集6只健康和6只腹泻北平顶猴的新鲜粪便,应用Illumina MiSeq高通量测序技术测定其肠道菌群的结构以及腹泻过程中肠道菌群的动态变化。结果表明:健康组肠道菌群的Shannon指数(P=0015)、Chao 1指数(P=0014)、ACE指数(P=0032)较腹泻组高。在门水平上,腹泻组肠道中拟杆菌门(Bacteroidetes)、变形菌门(Proteobacteria)和未鉴定细菌(unidentified ...
金洁 1   +5 more
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Gut microbiota dynamics of adult and sub‐adult sika deer during reintroduction 重引入过程中成年和亚成年梅花鹿肠道微生物的动态变化

open access: yesIntegrative Conservation, Volume 3, Issue 3, Page 257-270, September 2024.
Natural training enclosure design schematic. We selected 12 sika deer including six adults and six sub‐adults. Key considerations in the design of the natural training were to divide the training spatial ground into two parts (30 × 30 m small areas for isolation of new individuals and large areas measuring 200 × 600 m for free walking), and the ...
Wentao Zhang   +10 more
wiley   +1 more source

Longitudinal evaluation of the cutaneous and rectal microbiota of German shepherd dogs with perianal fistulas undergoing therapy with ciclosporin and ketoconazole

open access: yesVeterinary Dermatology, Volume 35, Issue 4, Page 375-385, August 2024.
Background – Perianal fistulas are painful ulcers or sinus tracts that disproportionately affect German shepherd dogs and are proposed as a spontaneous animal model of fistulising Crohn's disease. Objectives – To characterise the rectal and cutaneous microbiota in German shepherd dogs with perianal fistulas and to investigate longitudinal shifts with ...
Christine L. Cain   +6 more
wiley   +1 more source

肠道菌群变化在2型糖尿病诊疗中的价值

open access: yesZhongguo shiyan zhenduanxue, 2017
1肠道菌群与2型糖尿病人体胃肠道中存在着大量的正常菌群,其肠道内微生物主要由厚壁菌门、拟杆菌门、放线菌门、变形菌门以及疣微球菌门组成,而厚壁菌门及拟杆菌门占优势,某些病毒及真核生物也同时存在于肠道内[3]。肠道菌群和肥胖症的发生有很大的关系,其与2型糖尿病的关系亦是如此,有学者发现,改变肠道菌群构成 ...
宋丹丹, 刘煜
doaj  

圈养条件下不同年龄孟加拉白虎的肠道菌群研究

open access: yes野生动物学报, 2021
在圈养条件下,为了探知孟加拉白虎(Panthera tigris tigris)的肠道菌群结构以及不同年龄孟加拉白虎的肠道菌群差异,对亚成年和成年孟加拉白虎的粪便菌群进行高通量测序分析。结果表明:在2组白虎的肠道菌群中,放线菌门(Actinobacteria)和厚壁菌门(Firmicutes)最为优势,比例达80%以上;柯林斯菌属(Collinsella)比例最高,平均含量为438%,梭杆菌属(Fusobacterium)、布劳特氏菌属(Blautia)和瘤胃球菌类群(Ruminococcus ...
苏凯#雷英#金修哲李金邦
doaj  

饲料和不同生活时期对人工饲养大壁虎肠道菌群的影响

open access: yes野生动物学报, 2022
为了优化人工饲养大壁虎(Gekko gecko)的膳食结构及养殖程序,研究了蝗虫(Locusta migratoria manilensis)、黄粉虫(Tenebrio molitor)、土鳖虫(Eupolyphaga sinensis)及大麦虫(Zophobas morio)4种昆虫饲料对大壁虎生长速度的影响,并通过16S rDNA高通量测序技术比对了大壁虎胃肠道微生物菌群差异及冬眠期与捕食期的大壁虎胃肠道微生物菌群差异。结果表明:饲喂不同昆虫饲料对大壁虎的增重效果不同。单一昆虫饲料组中 ...
赵成坚 1 全琛宇 2 霍娟 1 徐永莉 1 姜建萍 1
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