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Gut Microbiota—A New Concern on Health Regulation(肠道菌群：膳食与健康研究的新视角) [PDF]
Shipin kexue jishu xuebao, 2015 With the development of “Human Microbiome Project” and “Metagenomics of the Human Intestinal Tract”, great attention has been paid on human gut microbiota. With the increasing knowledge of the composition and function of gut microbiota, we found that gut
CHEN Wei(陈 卫)
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Metabolic characteristics of polysaccharides from mulberries at different maturity stages during in vitro fecal fermentation [PDF]
ObjectiveThis study investigated the in vitro fermentation characteristics and gut microbiota modulation effects of polysaccharides extracted from mulberries at different maturity stages.MethodsPolysaccharides from green, red and purple mulberries were ...
CHEN Jianle +5 more
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Effects of Low-carbon and High Protein Bread Diet on Blood Lipid, Immune Index and Intestinal Flora in Mice [PDF]
Objective: To observe the effects of low carbohydrate and high protein diet (LC-HP) and high oil and high sugar diet on blood lipid, immune index and intestinal flora in mice. Use of high protein gluten as the main ingredient to make bread as the diet of
Dajun LI, Yuchun JIANG, Yuhang XIAO
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Cyanidin-3-O-glucoside Ameliorates Brain Damage by Modulating Gut Microbiota in Naturally Aging Mice [PDF]
Objective: To investigate the effect of cyanidin-3-O-glucoside (C3G) on brain damage and gut microbiota in naturally aging mice. Methods: Mice aged 2 and 18 months were divided into four groups: young control, young + C3G, aging model and aged + C3G. The
CHEN Yuyu, PENG Wenting, SONG Ge, FANG Wei, QI Wentao, WANG Yong
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Zhongshan Daxue xuebao. Yixue kexue ban, 2023 目的探讨甘草素（LG）对绝经前后APP/PS1小鼠肠道菌群的影响。方法将40只3月龄雌性APP/PS1双转基因小鼠随机分为假手术组 （sham， n=20）、去卵巢组（OVX， n=20）。术后第7天，将每组小鼠再分别用LG和生理盐水处理，另取10只野生型C57BL/6J小鼠作正常对照组（WT）。LG处理组剂量为30 mg•kg-1•d-1，药物处理90 d后，采集粪便样本，提取基因组，采用16S rDNA扩增子测序对各组小鼠的肠道菌群进行分析；利用水迷宫，评估小鼠的学习与记忆能力 ...
耿清华 +3 more
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Linchuang shenzangbing zazhi, 2016 人体菌群由总计超过1015、种类达5001000种细菌构成,数目达到人体本身细胞数的10倍以上[1],其中消化道承载了最多种类和数量的菌群。肠道菌群不仅参与了人体重要的营养物质代谢以及部分维生素的合成,还维持了肠道环境稳态,诱导免疫系统成熟和免疫耐受,肠道菌群所产生的代谢产物还可以影响心、肾等脏器以及血管的功能[2]。近20年来大量研究表明,慢性肾脏病（chronic kidney disease,CKD）与肠道菌群之间存在着密切的相互影响和作用 ...
张镭, 聂静
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野生动物学报, 2022 哺乳动物的肠道中存在庞大的微生物群落,这些微生物与宿主自身的消化吸收、能量代谢和免疫防御等生命活动息息相关。海南长臂猿(Nomascus hainanus)是世界上最濒危的灵长类动物之一,现存海南长臂猿种群小、分布范围狭窄、近亲繁殖隐患高,尚未摆脱物种灭绝风险,目前对该物种现存种群的肠道微生态研究匮乏。以海南热带雨林国家公园4个家庭群内的5只成年雄性海南长臂猿为研究对象,在旱季通过非损伤取样法及宏基因组学技术对采集到的粪便中的微生物进行测序分析和功能注释。结果表明 ...
李依蒙, 毕 玉, 金 崑
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Mechanism of Action of Lacticaseibacillus paracasei HNU502 and Fecal Microbiota Transplantation in Alleviating Antibiotic Side Effects [PDF]
Antibiotics are effective in treating bacterial infections, but they also disrupt the gut microbiota, thereby causing side effects such as diarrhea, flatulence and indigestion.
CHEN Lin, LI Ao, LI Jiahe, ZHANG Zeng, ZHANG Jiachao
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盐酸小檗碱对糖尿病患者血糖、胃肠激素及肠道菌群的影响 [PDF]
, 2019 目的探讨盐酸小檗碱对2型糖尿病患者胃泌素、胰高血糖素及肠道菌群的影响。方法选择我院单用胰岛素治疗的2型糖尿病患者25例为治疗组,选取同期体检中心体检健康人群10例为对照组。治疗组根据血糖情况调整胰岛素剂量,同时给予盐酸小檗碱每次500mg,tid,连续12周。分别于0、4、8、12周检测血糖、胃泌素、胰高血糖素,于0、12周采集清晨空腹粪便进行粪便菌群培养。结果治疗组治疗前后胃泌素水平均明显高于对照组(P0.05)。治疗组治疗前厚壁菌门高于治疗后及对照组水平 ...
吴埼淇 +5 more
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野生动物学报, 2023 为更好地监测马鹿（Cervus elaphus）的生存状态，有效促进隔离小种群复壮，使用16S rRNA高通量测序技术对内蒙古赛罕乌拉国家级自然保护区马鹿夏季肠道菌群多样性及结构进行分析。结果表明：拟杆菌门（Bacteroidetes，29.55%）、变形菌门（Proteobacteria，29.30%）、厚壁菌门（Firmicutes，29.30%）和放线菌门（Actinobacteria，5.78%）是马鹿主要优势菌门；拟杆菌属（Bacteroides，4.30%）、瘤胃球菌属 ...
刘夫仁 +6 more
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