Results 51 to 60 of about 2,568 (155)
Research Progress on Probiotics in Improving Mental Health of Older Adults [PDF]
As the global population is aging, elderly individuals are increasingly facing significant health challenges, especially mental health issues such as emotional problems, sleep disturbance, and cognitive impairment.
BO Zhihang, WANG Xinyu, YANG Zhenyu, ZHANG Guofang, DU Peng, LI Chun, LIU Libo
core +1 more source
Advances in Understanding the Role Mechanism of Dietary Fiber in Mitigating Colitis [PDF]
Colitis is an inflammatory intestinal disease that lasts for a long time, has an unknown cause, and occurs repeatedly. It is usually accompanied by symptoms such as intestinal cell damage, intestinal immunity, and abnormal intestinal flora.
Daling HE +5 more
core +1 more source
Regulation of Yeast Extract-Curcumin on Intestinal Flora in Mice with Acute Alcoholic Liver Injury [PDF]
Objective: This study aimed to investigate the protective effect and mechanism of yeast extract and curcumin-yeast extract on acute alcoholic liver injury in mice.
Haili YU +4 more
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小檗碱对口服降糖药糖尿病患者的胃肠激素及肠道菌群的影响 [PDF]
目的:探讨盐酸小檗碱对2型糖尿病(T2DM)胃泌素(GAS)、胰高血糖素(GLC)及肠道菌群的影响。方法:以25例口服降糖药治疗的T2DM患者为治疗组,对照组选取健康人群10例。T2DM患者常规治疗,同时给予盐酸小檗碱500 mg,每日3次,连续12周。分别于0、4、8、12周检测血糖、GAS、GLC,于0、12周采集清晨空腹粪便进行粪便菌群培养。结果:治疗组治疗后FPG及餐后1hPG有不同程度的下降 ...
吴埼淇 +5 more
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Effects of alginate oligosaccharides on depression-like behavior and gut microbiota in zebrafish induced by chronic unpredictable mild stress [PDF]
Objective To investigate the effects of alginate oligosaccharides (AOS) on depression-like behavior and gut microbiota in zebrafish, a model of chronic unpredictable mild stress (CUMS).
HE Naihuan +8 more
core +1 more source
目的探讨甘草素(LG)对绝经前后APP/PS1小鼠肠道菌群的影响。方法将40只3月龄雌性APP/PS1双转基因小鼠随机分为假手术组 (sham, n=20)、去卵巢组(OVX, n=20)。术后第7天,将每组小鼠再分别用LG和生理盐水处理,另取10只野生型C57BL/6J小鼠作正常对照组(WT)。LG处理组剂量为30 mg•kg-1•d-1,药物处理90 d后,采集粪便样本,提取基因组,采用16S rDNA扩增子测序对各组小鼠的肠道菌群进行分析;利用水迷宫,评估小鼠的学习与记忆能力 ...
耿清华 +3 more
doaj +2 more sources
哺乳动物的肠道中存在庞大的微生物群落,这些微生物与宿主自身的消化吸收、能量代谢和免疫防御等生命活动息息相关。海南长臂猿(Nomascus hainanus)是世界上最濒危的灵长类动物之一,现存海南长臂猿种群小、分布范围狭窄、近亲繁殖隐患高,尚未摆脱物种灭绝风险,目前对该物种现存种群的肠道微生态研究匮乏。以海南热带雨林国家公园4个家庭群内的5只成年雄性海南长臂猿为研究对象,在旱季通过非损伤取样法及宏基因组学技术对采集到的粪便中的微生物进行测序分析和功能注释。结果表明 ...
李依蒙, 毕 玉, 金 崑
doaj
Effect of Lactiplantibacillus plantarum P16 on Relieving DSS-induced Ulcerative Colitis [PDF]
Objective: To investigate the therapeutic effect of Lactiplantibacillus plantarum P16 on dextran sulfate sodium (DSS)-induced ulcerative colitis in mice. Methods: BALB/c male mice were randomly divided into 4 groups (n=10): control group, model group, L.
Qian CHENG, Yan ZHANG, Zhixian CHEN
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人体菌群由总计超过1015、种类达5001000种细菌构成,数目达到人体本身细胞数的10倍以上[1],其中消化道承载了最多种类和数量的菌群。肠道菌群不仅参与了人体重要的营养物质代谢以及部分维生素的合成,还维持了肠道环境稳态,诱导免疫系统成熟和免疫耐受,肠道菌群所产生的代谢产物还可以影响心、肾等脏器以及血管的功能[2]。近20年来大量研究表明,慢性肾脏病(chronic kidney disease,CKD)与肠道菌群之间存在着密切的相互影响和作用 ...
张镭, 聂静
doaj
为更好地监测马鹿(Cervus elaphus)的生存状态,有效促进隔离小种群复壮,使用16S rRNA高通量测序技术对内蒙古赛罕乌拉国家级自然保护区马鹿夏季肠道菌群多样性及结构进行分析。结果表明:拟杆菌门(Bacteroidetes,29.55%)、变形菌门(Proteobacteria,29.30%)、厚壁菌门(Firmicutes,29.30%)和放线菌门(Actinobacteria,5.78%)是马鹿主要优势菌门;拟杆菌属(Bacteroides,4.30%)、瘤胃球菌属 ...
刘夫仁 +6 more
doaj

