Results 71 to 80 of about 2,568 (155)
Progress in Study on Symptoms of Irritable Bowel Syndrome and Intestinal Gas [PDF]
, 2016 肠易激综合征(IBS)是临床较常见的慢性功能性肠道疾病,在我国发病率呈逐年上升趋势。目前IBS病因和发病机制仍未完全阐明,可能与肠道气体有关。肠道气体通常由59%N_2、21%H_2、9%CO_2、7%甲烷(CH_4)以及4%O_2组成,其中H_2和CH_4仅由肠道细菌代谢产生。IBS患者常表现为腹胀等肠胀气症状,提示存在肠道积气。近年来,IBS症状与肠道气体的关系备受关注,本文就IBS症状与肠道气体的研究进展作一综述。Irritable bowel syndrome( IBS) is a ...
刘妍 +4 more
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Research progress in mechanisms of gut microbiota in diabetic cognitive impairment and its targeted intervention [PDF]
Diabetes mellitus type 2 might cause mild cognitive impairment in its advanced stages, potentially progressing to dementia. Diabetic cognitive impairment (DCI) stands as a chronic complication of diabetes mellitus, with its underlying pathogenesis still ...
AN Yu +4 more
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Effects of in Vitro Culture with Chlorophyll a or b on the Fecal Flora Composition of High-Fat-Fed Mice and Metabolomic Analysis of Fermentation Products [PDF]
The objective of this study was to investigate the effect of chlorophyll a versus b on the intestinal flora of mice induced by a high-fat diet (HFD) metabolomics combined with microbial diversity analysis.
CHEN Yuyao, WANG Yuankai, ZENG Quanheng, ZHOU Chunjie, CAI Tian, CHEN Kewei
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野生动物学报, 2020 通过高通量测序技术，对采自贺兰山的20只阿拉善马鹿粪便进行测序及菌群多样性分析。结果表明，20个样品共获得1 564 112条序列，有效序列1 399 562条和2 740个OTUs。其中样品包含24个门和283个属，在门水平上核心菌门，分别是厚壁菌门（Firmicutes）76.71%、拟杆菌门（Bacteroidetes）14.16%、变形菌门（Proteobacteria）3.51%。在属水平上，核心菌属有11个，占肠道菌群的31.46%，分别为孢子杆菌属（Sporobacter）7.38 ...
李俊乐 1 +5 more
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野生动物学报, 2022 为提高褐马鸡(Crossoptilon mantchuricum)疾病防控能力和饲养管理水平,利用高通量测序技术对其肠道菌群进行多样性分析,探知其肠道菌群在不同季节的变化规律,并预测潜在致病的高发时间段,结果表明:门水平上,圈养褐马鸡的肠道优势菌群为厚壁菌门(Firmicutes,52.11%)、拟杆菌门(Bacteroidetes,18.20%)、变形菌门(Proteobacteria,17.91%)和放线菌门(Actinobacteria,7.32%); 属水平上 ...
雷 英 +11 more
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The causal relationship between gut microbiota and tinnitus based on Mendelian randomization [PDF]
Objective To explore the causal relationship between gut microbiota and tinnitus based on Mendelian randomization (MR) research method. Methods Data on the gut microbiota in individuals from the genome wide association study (GWAS) (n=18, 340) using the ...
GU Jing +8 more
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Protective Effect of Noni Polysaccharide on Ionizing Radiation Injury Mice and Its Effect on Intestinal Microbiota [PDF]
Objective: This study was to investigate the protective effect of Noni polysaccharides on ionizing radiation injury and its regulation of intestinal flora in mice.
Aixin LI +5 more
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Zhongguo shiyan zhenduanxue目前,中国已成为全球糖尿病患者最多的国家[1],随着糖尿病人群迅速增加,糖尿病肾病（DN）的发病率也逐步上升。在健康个体中,肠道菌群处于动态平衡状态;而当这种平衡被破坏时,就会产生各种疾病。继2011年国际透析大会首次提出“肠-肾轴”概念后[2],越来越多的学者把目光聚焦在肠道菌群对DN的作用机制方面。目前针对DN和肠道菌群关系的研究已经成为一个重要的突破口,纠正肠道菌群失调可能成为干预和治疗DN的新靶点。1 DN患者肠道菌群的组成肠道中的大量不同种类细菌统称为肠道菌群。通过现代测序技术分析 ...
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Zhongshan Daxue xuebao. Yixue kexue ban, 2012 【目的】构建体外模拟肠道共生系统，用于评价食源性抗菌药及其耐药菌作用于肠道菌群时对人体健康造成的危害风险。【方法】21d体外培养构建Caco-2细胞三维肠上皮，分成无菌对照组、混合的正常菌群组、沙门氏菌组、混合菌群-沙门氏菌组4组，制备混悬液，各组分别单独和混合培养4h，荧光定量PCR法测试共培养前后各菌16SrDNA菌量变化，电阻仪测试跨膜上皮电阻(TEER)数量；免疫荧光染色观察紧密连接蛋白ZO-1变化，评价三维肠上皮屏障功能的改变。【结果】 在体外共培养模型内 ...
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Zhongguo shiyan zhenduanxue, 2020 目的探讨肠道菌群及血清炎性因子联合检测在炎症性肠病(inflammatory bowel disease,IBD)中的诊断价值。方法选取2017年6月至2018年5月我院收治的IBD患者174例作为实验对象,根据病情的分期分组,分为活动期组和缓解期组。同时,选取同期在我院进行健康体检者30例作为对照组。分别采集各组新鲜粪便,培养样本并分析肠道菌群。此外,采集各组外周静脉血,采用酶联免疫吸附法(enzyme-linked immuno sorbent assay,ELISA)分别检测各组血清IL-6 ...
杨文宏, 王维维
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