Results 71 to 80 of about 2,196 (154)
Gut microbiota and thyroid-associated ophthalmopathy. [PDF]
Zhong Nan Da Xue Xue Bao Yi Xue Ban, 2023 Zhao J, Wang P, Jiang M, Yan S.
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盐酸小檗碱对糖尿病患者血糖、胃肠激素及肠道菌群的影响 [PDF]
, 2019 目的探讨盐酸小檗碱对2型糖尿病患者胃泌素、胰高血糖素及肠道菌群的影响。方法选择我院单用胰岛素治疗的2型糖尿病患者25例为治疗组,选取同期体检中心体检健康人群10例为对照组。治疗组根据血糖情况调整胰岛素剂量,同时给予盐酸小檗碱每次500mg,tid,连续12周。分别于0、4、8、12周检测血糖、胃泌素、胰高血糖素,于0、12周采集清晨空腹粪便进行粪便菌群培养。结果治疗组治疗前后胃泌素水平均明显高于对照组(P0.05)。治疗组治疗前厚壁菌门高于治疗后及对照组水平 ...
吴埼淇 +5 more
core
Lowering Blood Lipids and Regulating Intestinal Flora Effects of Blueberry Enzyme in Hyperlipidemic Mice [PDF]
The effects of blueberry enzyme on dysregulated lipid metabolism and intestinal microbiota in hyperlipidemic mice were investigated, using blueberry juice as a control, they were divided into normal group, model group, simvastatin group, high-dose ...
Binyan YANG +3 more
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Zhongguo shiyan zhenduanxue目前,中国已成为全球糖尿病患者最多的国家[1],随着糖尿病人群迅速增加,糖尿病肾病（DN）的发病率也逐步上升。在健康个体中,肠道菌群处于动态平衡状态;而当这种平衡被破坏时,就会产生各种疾病。继2011年国际透析大会首次提出“肠-肾轴”概念后[2],越来越多的学者把目光聚焦在肠道菌群对DN的作用机制方面。目前针对DN和肠道菌群关系的研究已经成为一个重要的突破口,纠正肠道菌群失调可能成为干预和治疗DN的新靶点。1 DN患者肠道菌群的组成肠道中的大量不同种类细菌统称为肠道菌群。通过现代测序技术分析 ...
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Research Advances in the Role of Cereal Dietary Fiber in Modulating Glucose and lipid Metabolism via the Gut Microbiota-Bile Acid [PDF]
Disorders in glucose and lipid metabolism are closely linked to chronic metabolic diseases, including obesity, non-alcoholic fatty liver, hyperlipidemia and diabetes.
DONG Hong-wang +4 more
core +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2012 【目的】构建体外模拟肠道共生系统，用于评价食源性抗菌药及其耐药菌作用于肠道菌群时对人体健康造成的危害风险。【方法】21d体外培养构建Caco-2细胞三维肠上皮，分成无菌对照组、混合的正常菌群组、沙门氏菌组、混合菌群-沙门氏菌组4组，制备混悬液，各组分别单独和混合培养4h，荧光定量PCR法测试共培养前后各菌16SrDNA菌量变化，电阻仪测试跨膜上皮电阻(TEER)数量；免疫荧光染色观察紧密连接蛋白ZO-1变化，评价三维肠上皮屏障功能的改变。【结果】 在体外共培养模型内 ...
doaj
Zhongguo shiyan zhenduanxue, 2020 目的探讨肠道菌群及血清炎性因子联合检测在炎症性肠病(inflammatory bowel disease,IBD)中的诊断价值。方法选取2017年6月至2018年5月我院收治的IBD患者174例作为实验对象,根据病情的分期分组,分为活动期组和缓解期组。同时,选取同期在我院进行健康体检者30例作为对照组。分别采集各组新鲜粪便,培养样本并分析肠道菌群。此外,采集各组外周静脉血,采用酶联免疫吸附法(enzyme-linked immuno sorbent assay,ELISA)分别检测各组血清IL-6 ...
杨文宏, 王维维
doaj
Progress in Study on Symptoms of Irritable Bowel Syndrome and Intestinal Gas [PDF]
, 2016 肠易激综合征(IBS)是临床较常见的慢性功能性肠道疾病,在我国发病率呈逐年上升趋势。目前IBS病因和发病机制仍未完全阐明,可能与肠道气体有关。肠道气体通常由59%N_2、21%H_2、9%CO_2、7%甲烷(CH_4)以及4%O_2组成,其中H_2和CH_4仅由肠道细菌代谢产生。IBS患者常表现为腹胀等肠胀气症状,提示存在肠道积气。近年来,IBS症状与肠道气体的关系备受关注,本文就IBS症状与肠道气体的研究进展作一综述。Irritable bowel syndrome( IBS) is a ...
刘妍 +4 more
core
Zhongguo shiyan zhenduanxue目的探讨肠道菌群构成在变应性鼻炎（AR）发病机制中的作用。方法卵清蛋白致敏法构建AR豚鼠模型，并对模型进行布地奈德干预。采用16S rRNA基因测序检测菌群构成，分析AR鼻腔及肠道菌群组成特征及相关代谢通路，并筛选可能与症状改善相关的有益菌群。结果（1）与正常对照组相比，AR鼻腔菌群中绿弯菌门，芽孢杆菌纲，魏斯氏菌属的相对丰度增高；肠道菌群结构变化更为复杂，蓝藻门，吸血鬼弧菌纲，钩端螺旋菌纲，微球菌目，梭菌目等菌属相对丰度显著升高。（2）与健康对照组相比，AR鼻腔菌群涉及代谢通路无显著变化 ...
李敏, 于歌, 杨雯棋, 李琳
doaj
The analysis of intestinal microflora in infants with cow's milk protein allergy [PDF]
Objective To explore the changes of intestinal microflora diversity and phylum species abundance in infants with cow's milk protein allergy (CMPA), so as to provide theoretical basis for early prevention and treatment of CMPA infants.
DONG Guoqing +7 more
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