2 型固有淋巴细胞主导的小鼠呼吸道变应性炎症模型的建立 [PDF]
Zhongshan Daxue xuebao. Yixue kexue ban, 2019 【目的】应用野生型C57BL/6小鼠和T/B细胞缺陷的Rag1-/-小鼠建立以2型固有淋巴细胞（ILC2）为主导的小鼠呼吸道变应性炎症模型。【方法】分别将雌性C57BL/6小鼠和Rag1-/-小鼠随机平均分为对照组和实验组，并分别于第1、3、5天经气道滴注给予20μLddH2O或含1μgIL-33的ddH2O。第6天处死小鼠后收集肺泡灌洗液和肺组织，通过病理染色及流式检测炎症细胞浸润，通过酶联免疫吸附实验检测细胞因子水平及应用流式检测ILC2水平。【结果】C57BL/6和Rag1 ...
孟祥慈
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Goodpasture syndrome complicated with lung infection: a case report and literature review [PDF]
, 2023 Objective To investigate the clinical characteristics， diagnosis and treatment of Goodpasture syndrome complicated with lung infection. Methods Clinical data of one case of Goodpasture syndrome complicated with pulmonary infection were retrospectively ...
Cen Tiantian, Zhang Xiaoqun, Ma Hongying
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Structure of an Acidic Polysaccharide from Brassica rapa L. and Its Protective Effect on Lipopolysaccharide-Induced Lung Injury in Mice [PDF]
, 2023 Objective: To study the structure of BRAP-1, an acidic polysaccharide from Brassica rapa L. and its effect and mechanism on lipopolysaccharide (LPS)-induced lung injury in mice.
Kadierya·KUERBAN, Ajiranmu·Abula, CHEN Zhuo’er, Miherenisha·AMUREJIANG, Hailiqian·TAOERDAHONG, YANG Fei
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Macrophage differential genes and their functions in silicosis based on single cell RNA sequencing and spatial transcriptome sequencing [PDF]
, 2022 BackgroundThe rise of single cell RNA sequencing (scRNA-seq) and spatial transcriptome sequencing technologies has allowed for intensive study of lung diseases, but both have been poorly studied in silicosis.
Jie CHAO, Wei ZHANG, Xinbei ZHOU
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Research progress on the relationship between lung microbiome and lung cancer [PDF]
, 2023 Lung cancer is the leading cause of cancer-related deaths worldwide. Lung microbiome is defined as the microbial organisms located in the lung. With rapid development of next-generation sequencing， microbiome has been found to affect the host’s nutrition，
Ge Yijun, Cao Chao
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The Study of the Value of High Mobility Group Protein B1 Combined with Acute Physiological Score in the Diagnosis and Prognosis of Children with Severe Pneumonia [PDF]
, 2022 BackgroundSevere pneumonia in children is a common respiratory critical illness, and accurate assessment of its prognosis is the key to reasonable clinical decision-making. High mobility group protein B1 (HMGB1) and acute physiology score (APS) have high
KANG Ping, LI Yi, TANG Yu
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Review of CD4+ T cell subsets in asthma phenotypes: molecular mechanisms and biologic treatment options [PDF]
, 2023 Asthma is a chronic inflammatory airway disease, mainly driven by different CD4+ T cell subsets [helper T cell (Th cell)]. CD4+ T cell subsets are a type of important immune cells, capable of secreting various cytokines, and regulating the immune ...
WANG Chuanping, ZHAO Yanhong
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Research progress of immune response regulated by epigenetic modification in pneumonia [PDF]
, 2023 Pneumonia is one of the most common infectious diseases, and although considerable progress has been made in the diagnosis and treatment of pneumonia, it is still associated with high mortality, prolonged hospitalization, and significant medical ...
HAN Xiao, WANG Qing, ZHANG Xiaobo
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Diabetic ketoacidosis complicated with hypophosphatemia and Aspergillus fumigatus pneumonia: a case report and literature review [PDF]
, 2023 Objective To investigate the clinical characteristics of hypophosphatemia in diabetic ketoacidosis （DKA） complicated with pulmonary infection.
Qiu Ruizhen, Wu Ying, Yan Qiaolu, Zhang Ping
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Changes and significance of TLR7/9 and IFN-Ⅰ levels in children with severe mycoplasma pneumoniae pneumonia [PDF]
, 2023 Objective To investigate the changes and significance of Toll-like receptor 7 （TLR7）， TLR9 and type I interferon （IFN-Ⅰ） in children with severe mycoplasma pneumoniae pneumonia （SMPP）.
Yan Jiangxue, Ding Xia, Jiao Qiongjie, Huang Li, Cao Nannan, Dong Xinfang, Ni Qian
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