Diabetic ketoacidosis complicated with hypophosphatemia and Aspergillus fumigatus pneumonia: a case report and literature review [PDF]
, 2023 Objective To investigate the clinical characteristics of hypophosphatemia in diabetic ketoacidosis （DKA） complicated with pulmonary infection.
Qiu Ruizhen, Wu Ying, Yan Qiaolu, Zhang Ping
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Changes and significance of TLR7/9 and IFN-Ⅰ levels in children with severe mycoplasma pneumoniae pneumonia [PDF]
, 2023 Objective To investigate the changes and significance of Toll-like receptor 7 （TLR7）， TLR9 and type I interferon （IFN-Ⅰ） in children with severe mycoplasma pneumoniae pneumonia （SMPP）.
Yan Jiangxue, Ding Xia, Jiao Qiongjie, Huang Li, Cao Nannan, Dong Xinfang, Ni Qian
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儿童下气道菌群多样性及其对支气管哮喘辅助性T细胞分化机制影响研究进展 [PDF]
, 2018 哮喘是由多种细胞(如嗜酸性粒细胞、肥大细胞、T淋巴细胞、中性粒细胞、气道上皮细胞等)和细胞组分参与的以慢性气道炎症和气道高反应性为特征的一种异质性疾病[1]。近年来哮喘发病率逐年攀升,据全球哮喘防治创议(GINA)委员会调查显示,全球约有3亿人受到哮喘困扰[2],世界卫生组织(WHO)预计至2025年全世界哮喘患者将会增至4亿人。研究发现,哮喘患者气道菌群在丰度及多样性等方面与正常人存在显著差异[3 ...
侯凌云, 吴谨准, 葛丹丹
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Effect of Qufeng Xuanbi Formula on experimental asthma guinea pigs' airway inflammation and Th1/Th2 cytokines [PDF]
目的 观察祛风宣痹方对哮喘豚鼠气道炎症和Th1/Th2细胞因子的影响，探讨其作用机制。方法 用卵蛋白和雾化吸入致敏法，复制豚鼠哮喘模型；取肺泡灌洗液进行嗜酸性粒细胞(Eos)计数；肺组织切片HE染色形态学观察；ELASA方法检测BALF中IFN-γ和IL-4的含量。结果 模型组较正常组肺泡灌洗液(BALF)中气道Eos炎症细胞表达异常，组织形态学病变明显，IFN-γ含量显著下降，IL-4的含量明显升高；地塞迷松米组、中药高剂量组、中药低剂量组较模型组均有显著性差异，BALF中Eos的数量明显降低 ...
Shi, Suo-fang, Zhou, Kui-long
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Effect of montelukast on leukotriene B4 metabolism in asthma [PDF]
, 2023 Objective·To observe the effect of montelukast on the expressions of key genes in LTB4 (leukotriene B4) metabolic pathway in treating asthma and investigate the candidate intervene targets of asthma.Methods·The acute, subacute, and chronic asthmatic ...
FU Hongling +6 more
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Diagnotic Value of the Combined Determination of Telomerase Activity in Induced Sputum, Pleural Effusion and Fiberobronchoscopic Biopsy Samples in Lung Cancer [PDF]
, 2010 Background and objective It has been proven that telomerase activation correlates with the carcinogenesis, aggressiveness and turnover of lung cancer.
Cheng ZHAO +4 more
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Effects and mechanisms of Pd-Ia on LPS-induced acute lung injury in mice [PDF]
, 2016 目的：随着环境的不断恶化，空气质量越来越差，并且已经严重影响到了人们的身体健康，雾霾已经遍布中国的众多城市，使得呼吸系统疾病的发病率日渐升高。急性肺损伤（ALI）/急性呼吸窘迫综合征（ARDS）都是比较常见的临床呼吸系统疾病，ARDS对于临床疾病来说，可谓是灾难性的，属于严重的呼吸衰竭，目前无有效的药物治疗措施。ALI是ARDS的早期阶段，其特点是弥漫性的炎症损伤，目前研究发现中药白花前胡根中提取出的活性成分白花前胡甲素（Pd-Ia）在LPS诱导的内皮细胞炎症损伤中具有良好的抗炎效果 ...
周晓霞
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Role of exosome-derived miRNA-21-5p/Smad7 in quartz dust-induced pulmonary fibrosis in rats [PDF]
BackgroundQuartz dust cannot be degraded in the lungs, and inhalation of a large amount of quartz dust in the occupational production process will lead to the occurrence of pulmonary fibrosis, and then develop into silicosis.
Jiarui HAO +6 more
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Fulminant psittacosis complicated with multiple organ dysfunction syndrome: a case report [PDF]
, 2023 The cases of fulminant psittacosis complicated with multiple organ dysfunction syndrome （MODS） have been rarely reported in China. In this article， clinical manifestations and treatment of a patient with fulminant psittacosis complicated with MODS were ...
Qian Xueqin, Wang Yi, Zhang Huitao, Shen Dezhi, Huang Kaizhuang, Zhu Yaoli
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Combined use of venetoclax and azacitidine in treatment of acute myeloid leukemia complicated with disseminated Fusarium infection: a case report [PDF]
, 2022 Acute myeloid leukemia （AML） is a malignant clonal disease originating from hematopoietic stem/progenitor cells. Chemotherapy is the main treatment. If not effectively treated after 2 courses of standard treatment， these patients can be diagnosed with ...
Guo Jun, Wei Pei, Tong Yajun, Chen Ting
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