Results 21 to 30 of about 94,351 (149)

肺癌冶療の新戦略 [PDF]

open access: yes
わが国において、肺癌の羅患数は年々増加してきており、現在、その死亡率は悪性腫瘍のなかで最も高くなっている。肺癌全体の約80%以上を占める非小細胞肺癌においては、そのうち約80%が手術不能なⅢ期およびⅣ期の症例であり、肺癌全体の約20%を占める小細胞肺癌においても、そのうち約60%が進展型の症例である。いずれも手術不能な場合が大半を占めているため、肺癌の5年生存率は15%にも満たないのが現状である。1990年以降、新規抗漉剤の登場により肺癌の治療は進歩しつつあり、現在 ...
福岡, 正博
core   +1 more source

隣接臓器合併切除を伴う肺癌手術 [PDF]

open access: yes, 2006
今日でもなお発見される多くが進行肺癌であり,化学療法や放射線療法を主体とした治療がなされているが,その予後は一般に不良である.一方外科切除は肺癌治療において現在もなお唯一信頼性の高い根治療法であり,局所進行肺癌例に対して日常臨床として隣接臓器合併切除が行われている.隣接臓器浸潤はTNM分類上T3またはT4に区分され,一般的に切除可能と思われる臓器への浸潤を示す腫瘍はT3とされ,切除不能と考えられる臓器浸潤を伴う腫瘍がT4とされている.T3病変に対する外科治療は一般化してはいるが ...
Yokoi, Kohei, 横井, 香平
core  

Laser‐Induced Graphene/AuNPs‐Gated OECT Biosensor for Sensitive Detection of PD‐L1‐Positive Exosomes Associated With Non‐Small Cell Lung Cancer

open access: yesRare Metals, Volume 45, Issue 10, October 2026.
ABSTRACT Lung cancer remains a major cause of cancer‐related mortality worldwide, and non‐small cell lung cancer (NSCLC) accounts for the largest proportion of diagnosed lung cancer cases. Exosomal programmed death‐ligand 1 (PD‐L1) has attracted increasing attention as a potential liquid‐biopsy biomarker associated with tumor immune regulation; however,
Chen Su   +6 more
wiley   +1 more source

Abstracts

open access: yes, 2022
Cancer Science, Volume 113, Issue S1, Page 1-1874, February 2022.
wiley   +1 more source

A Locally Retentive HfO2–STING Nano‐Radiosensitizer Hydrogel for Enhanced Radioimmunotherapy in Esophageal Cancer

open access: yesRare Metals, Volume 45, Issue 9, September 2026.
ABSTRACT Esophageal squamous cell carcinoma (ESCC) remains associated with frequent local recurrence and distant metastasis despite advances in radiochemotherapy and immunotherapy, highlighting the need for therapeutic strategies that improve both local tumor control and systemic antitumor immune responses.
Dongdong Wang   +7 more
wiley   +1 more source

1肺葉内に同時期に発生した稀な肺癌との重複癌症例の検討 : 肺癌との重複癌II [PDF]

open access: yes, 1976
肺癌 = Japanese Journal of Lung Cancer, 16(3), p.258 ...
籠手田, 恒敏   +11 more
core   +1 more source

当院における間質性肺炎合併肺癌手術例 [PDF]

open access: yes
特発性間質性肺炎(idiopathic interstitial pneumonia以下IIPとする)に肺癌を合併する頻度は少なくない。今回、当院において最近経験した間質性肺炎合併肺癌の2症例に対し縮小手術を行い、いずれも周術期のIIP急性増悪なく経過は良好であった。IIP合併肺癌の治療は ...
堤, 正夫   +7 more
core   +1 more source

Ultrathin MnO2‐PEG‐PD‐L1 Nanosheets Enable Tumor Microenvironment Modulation and NIR‐II Photothermal Immunotherapy for Durable Control of Lung Cancer and Postoperative Recurrence

open access: yesRare Metals, Volume 45, Issue 6, June 2026.
ABSTRACT Lung cancer is one of the most common and deadly malignancies worldwide. Although immune checkpoint inhibitors, including PD‐1/PD‐L1 blockers, have benefited a subset of patients, response rates remain limited, and recurrence is frequent because of the immunosuppressive tumor microenvironment (TME), characterized by hypoxia and dysregulated ...
Yi Ma   +6 more
wiley   +1 more source

Retrospective efficacy analysis of immune checkpoint inhibitors in patients with EGFR‐mutated non‐small cell lung cancer

open access: yesCancer Medicine, Volume 8, Issue 4, Page 1521-1529, April 2019., 2019
It remains unclear EGFR‐mutated patients who have clinical outcomes of Immune checkpoint inhibitors (ICIs). In this study, we revealed the clinical factor of ICI responders among EGFR‐mutated NSCLC. Uncommon mutation and without T790M mutation are associated to ICI efficacy.
Tadaaki Yamada   +16 more
wiley   +1 more source

肺癌患者における肺血行(主にx線による研究) : (III)肺癌の早期診断 [PDF]

open access: yes, 1966
肺癌 = Japanese Journal of Lung Cancer, 6, p.31 ...
玉木, 正男   +3 more
core   +1 more source

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