Expression and Significance of gp96 and Immune-related Gene CTLA-4, CD8 in Lung Cancer Tissues [PDF]
, 2010 Background and objective It has been proven that gp96 plays an important role in specific cytotoxic immune response which is involved in anti-tumor effect in the body.
Haiyan ZHENG +4 more
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Diagnotic Value of the Combined Determination of Telomerase Activity in Induced Sputum, Pleural Effusion and Fiberobronchoscopic Biopsy Samples in Lung Cancer [PDF]
, 2010 Background and objective It has been proven that telomerase activation correlates with the carcinogenesis, aggressiveness and turnover of lung cancer.
Cheng ZHAO +4 more
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Comparative Analysis of Clinical Epidemiology and Pathological Characteristics of 908 Patients with Primary Lung Cancer of Hunan Province in 1997 and 2007 [PDF]
, 2010 Background and objective Epidemiology of lung cancer will be changed along with time and region. The aim of this study is to acknowledge the tendency of primary lung cancer in hunan province in recent years by comparing and analyzing the distribution of ...
Chengping HU +4 more
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Comparative Proteomics Study on Human High-metastatic Large Cell Lung Cancer Cell Lines Before and After Transfecting with nm23-H1 Gene [PDF]
, 2010 Background and objective As a tumor metastasis suppressor gene, the functions of nm23-H1 gene are still unclear. The aim of this study is to better understand the mechanism of lung cancer metastasis and to find new biomarkers for early diagnosis and new ...
Li MA +6 more
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The Impact of Smoking Status on the Efficacy of Erlotinib in Patients with Advanced Non-small Cell Lung Cancer [PDF]
, 2009 Background and objective Erlotinib is a targeted treatment for advanced non-small cell lung cancer. Smoking status may be one of influencing factors of the efficacy of erlotinib.
Jinji YANG +5 more
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响 Impact on the apoptosis, invasion, proliferation ET-1 interfere with the formation of lung cancer [PDF]
, 2015 摘要 目的: 肺癌是最常见的恶性肿瘤之一,威胁着全世界人民生命和健康。同时它也是世界上发病率和死亡率增长最快的疾病之一。而且大多数肺癌患者到晚期才被诊断发现，在现阶段肺癌的治疗中，它仍然是无法治愈的。Endothelin(ET),由内皮细胞合成，是一种生物活性肽,是一种强烈的血管收缩剂，具有很强的收缩血管作用,随着对内皮素研究的不断深入，人们发现内皮素与肿瘤关系密切，对肿瘤细胞的生长、增殖、转移、凋亡及化学耐药等都方面都有影响。ET能够产生细胞生长因子可以促进肿瘤DNA合成,基因表达和肿瘤细胞增殖 ...
张振宇
core
Zhongguo shiyan zhenduanxue, 2007 目的研究肝细胞生长因子（简称HGF/SF）表达与肺癌微血管密度及肺癌预后的相关性。方法应用免疫组化方法和图像分析仪分析对49例手术切除非小细胞肺癌（NSCLC）标本进行检测分析。结果HGF阳性表达率63.3%,HGF阳性表达主要出现肺癌组织中癌细胞胞浆内,HGF表达与肺癌的微血管生成及肺癌的进展有关,其中Ⅲ期肺癌组HGF阳性率为85.7%高于Ⅰ、Ⅱ期组 ...
刘静 +4 more
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亚洲临床医学杂志, 2020 近年来，基因组学、转录组学和蛋白质组学的重大进展改变了我们对肺癌发病机理的分子机制的理解，并正在彻底改变我们的诊断和治疗方法。虽然这些技术传统上被描述为对手术切除的肿瘤进行大体积活检，但重大的技术进步使它们可以应用于支气管镜下获得的较小样本，这通常是晚期肺癌唯一可用的样本。使用先进的分子技术进行组织学检查的手段包括：通过荧光原位杂交技术对非小细胞肺癌的早期诊断和筛查；通过新的免疫组织化学标记进行准确的组织学诊断以及靶向和常规化疗药物的预后和反应预测。分子生物学技术越来越多地应用于较小的活检标本 ...
东海 王 +4 more
semanticscholar +1 more source
Zhongguo shiyan zhenduanxue, 2019 肺癌占所有新癌症病例的12.4%[1],是全球癌症死亡的主要原因。肺空洞一般定义为肺实变、肿块或结节内的含气空腔[2]。癌性空洞为肺空洞性疾病的常见病因,肺空洞的形成在肺鳞状细胞癌（SCC）中最为常见,并且多提示预后不佳[3]。在一项对244例肺部恶性疾病患者的调查中,27例患者（11%）为空洞性肺癌。其中26例为原发性肺癌,21例为SCC[4]。引起肺空洞的其他原因包括结核分枝杆菌感染 ...
孔田田, 岳小山, 秦玉娇, 盛辉
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