Results 11 to 20 of about 6,663 (174)

The role of miRNAs carried by extracellular vesicles in type 2 diabetes and its complications 外泌体miRNA在2型糖尿病及其并发症中的作用

Journal of Diabetes, Volume 15, Issue 10, Page 838-852, October 2023., 2023
Highlights This review outlines the history of miRNA discovery and its major advances in the field of metabolism. We explore the roles of miRNAs in diabetes‐related cognitive impairment. We innovatively propose that miRNAs also act with a certain organ‐targeting specificity due to the organ‐targeting nature of extracellular vesicles, which may aid ...
Yining Chao, Tianwei Gu, Zhou Zhang, Tianyu Wu, Jin Wang, Yan Bi   +5 more
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Sex differences in risk factors for end‐stage kidney disease and death in type 2 diabetes: A retrospective cohort study 2型糖尿病终末期肾病和死亡危险因素的性别差异:一项回顾性队列研究

Journal of Diabetes, Volume 15, Issue 3, Page 246-254, March 2023., 2023
Highlights Sex differences are observed in the progression of chronic kidney disease; however, it is uncertain whether sex is associated with the risk of kidney failure in type 2 diabetes. In this multicenter cohort study, men had a higher risk of end‐stage kidney disease (ESKD) than women, and moderately increased albuminuria was strongly associated ...
Megumi Oshima, Yasunori Iwata, Tadashi Toyama, Shinji Kitajima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kengo Furuichi, Masakazu Haneda, Tetsuya Babazono, Hiroki Yokoyama, Kunitoshi Iseki, Shinichi Araki, Toshiharu Ninomiya, Shigeko Hara, Yoshiki Suzuki, Masayuki Iwano, Eiji Kusano, Tatsumi Moriya, Hiroaki Satoh, Hiroyuki Nakamura, Hirofumi Makino, Takashi Wada   +22 more
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Effect of sodium‐glucose cotransporter 2 inhibitors on the rate of decline in kidney function: A systematic review and meta‐analysis 钠‐葡萄糖共转运蛋白2抑制剂对肾功能下降速度的影响:系统综述和meta分析

Journal of Diabetes, Volume 15, Issue 1, Page 58-70, January 2023., 2023
Highlights Sodium/glucose cotransporter‐2 inhibitors (SGLT‐2i) showed an important renoprotective effect on sustained administration, regardless of the presence of diabetes, the baseline estimated glomerular filtration rate (eGFR) and different types of SGLT‐2i. There was an acute decline of eGFR in the initial administration (4.02 ml/min/1.73 m2), and
Yanbei Duo, Junxiang Gao, Tao Yuan, Weigang Zhao   +3 more
wiley   +1 more source

A novel index, Chinese visceral adiposity index is closely associated with urinary albumin‐creatinine ratio in Chinese community adults, especially in hypertensive or hyperglycemic population: Results from the REACTION study 一个新的指标, 中国人内脏脂肪指数与中国社区成年人(特别是高血压或高血糖人群)尿白蛋白‐肌酐比值密切相关:来自REACTION研究的结果

Journal of Diabetes, Volume 14, Issue 12, Page 792-805, December 2022., 2022
Highlights This is the first large‐sample, multicenter study of the relationship between Chinese Visceral Adiposity Index (CVAI) and urinary albumin to creatinine ratio (UACR) in Chinese community adults. CVAI and UACR were significantly associated in both genders. At higher CVAI levels, the population with prediabetes, diabetes, and hypertension has a
Binqi Li, Weiqing Wang, Zhengnan Gao, Xulei Tang, Li Yan, Qin Wan, Zuojie Luo, Guijun Qin, Lulu Chen, Guang Ning, Yiming Mu   +10 more
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Association between metabolic phenotype and urinary albumin‐creatinine ratio in Chinese community adults: A cross‐sectional study 中国社区成人代谢表型与尿白蛋白/肌酐比值的关系:一项横断面研究

Journal of Diabetes, Volume 14, Issue 8, Page 541-550, August 2022., 2022
HighlightsThis is the first multicenter, large‐sampled cross‐sectional study of the association between different metabolic phenotypes and urinary albumin‐creatinine ratio (UACR) in Chinese community adults. Our study may be helpful for people with increased albuminuria.
Yue Zhang, Binqi Li, Yang Liu, Wenxing Gao, Kang Chen, Anping Wang, Xulei Tang, Li Yan, Zuojie Luo, Guijun Qin, Lulu Chen, Qin Wan, Zhengnan Gao, Weiqing Wang, Guang Ning, Yiming Mu   +15 more
wiley   +1 more source

Increased neutrophil count Is associated with the development of chronic kidney disease in patients with diabetes 中性粒细胞计数升高与2型糖尿病患者慢性肾脏病变的发展相关

Journal of Diabetes, Volume 14, Issue 7, Page 442-454, July 2022., 2022
HighlightsNeutrophil count was an independent risk factor for CKD in patients with diabetes, especially when it exceeded 3.6 × 109/L, and increased neutrophil count could predict progression of CKD in patients with diabetes. Abstract Background This study aims to investigate the potential association of peripheral inflammatory blood cell parameters ...
Rui Zhang, Jin Chen, Yanqin Xiong, Lihong Wang, Xinmei Huang, Tiange Sun, Bingbing Zha, Yueyue Wu, Cuili Yan, Shufei Zang, Qin Zhou, Zhe Huang, Jun Liu   +12 more
wiley   +1 more source

Current gaps in management and timely referral of cardiorenal complications among people with type 2 diabetes mellitus in the Middle East and African countries: Expert recommendations 目前中东和非洲国家2型糖尿病患者在管理和及时转诊心肾并发症方面的差距:专家建议

Journal of Diabetes, Volume 14, Issue 5, Page 315-333, May 2022., 2022
Highlights This consensus document identifies challenging areas and strategic recommendations for the effective management of cardiorenal complications in type 2 diabetes mellitus in the Middle East and North Africa and Africa. There is a need for optimum glycemic control, early identification of cardiorenal complications, along with risk management ...
Alper Sonmez, Hani Sabbour, Akram Echtay, Abbas Mahdi Rahmah, Amani Matook Alhozali, Fahad Sulman al Sabaan, Fares H. Haddad, Hinde Iraqi, Ibrahim Elebrashy, Samir N. Assaad, Zaheer Bayat, Zeynep Osar Siva, Mohamed Hassanein   +12 more
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Kidney disease parameters, metabolic goal achievement, and arterial stiffness risk in Chinese adult people with type 2 diabetes 中国成年2型糖尿病患者的肾脏疾病参数、代谢目标实现情况和动脉硬化风险

Journal of Diabetes, Volume 14, Issue 5, Page 345-355, May 2022., 2022
Highlights Provide key information on the correlation between kidney disease measures and arterial stiffness by evaluating urine albumin‐creatinine ratio and estimated glomerular filtration rate simultaneously in a large sample with type 2 diabetes. Improving management of arterial stiffness, before reaching the chronic kidney disease stage, should ...
Chen Xu, Li Li, Juan Shi, Bangqun Ji, Qidong Zheng, Yufan Wang, Tingyu Ke, Li Li, Dong Zhao, Yuancheng Dai, Fengmei Xu, Ying Peng, Yifei Zhang, Qijuan Dong, Weiqing Wang   +14 more
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C3c deposition predicts worse renal outcomes in patients with biopsy‐proven diabetic kidney disease in type 2 diabetes mellitus C3c沉积可预测2型糖尿病患者经活检证实的糖尿病肾病更差的肾脏结局

Journal of Diabetes, Volume 14, Issue 4, Page 291-297, April 2022., 2022
Highlights C3c deposition in the kidney was associated with worse renal outcomes and was an independent predictor for ESRD in DKD patients with T2DM. C3c deposition in the kidney might be a novel biomarker indicating DKD progression in T2DM. Abstract Background Although extensive efforts have been paid to identify reliable predictors for renal outcomes
Meng‐Rui Li, Zi‐Jun Sun, Dong‐Yuan Chang, Xiao‐Juan Yu, Su‐Xia Wang, Min Chen, Ming‐Hui Zhao   +6 more
wiley   +1 more source

Combining glomerular basement membrane and tubular basement membrane assessment improves the prediction of diabetic end‐stage renal disease 联合评估肾小球基底膜厚度和肾小管基底膜厚度可提高糖尿病肾病进展为终末期肾脏病的预测能力

Journal of Diabetes, Volume 13, Issue 7, Page 572-584, July 2021., 2021
Highlights The prognostic value of combining tubular basement membrane (TBM) and glomerular basement membrane (GBM) in diabetic nephropathy (DN) was lacking. TBM thickness was strongly correlated with GBM thickness, baseline estimated glomerular filtration rate, and proteinuria. The degree of TBM thickness provided additional value to GBM thickness for
Lijun Zhao, Junlin Zhang, Song Lei, Honghong Ren, Yutong Zou, Lin Bai, Rui Zhang, Huan Xu, Lin Li, Yuancheng Zhao, Mark E. Cooper, Nanwei Tong, Jie Zhang, Fang Liu   +13 more
wiley   +1 more source