Results 51 to 60 of about 4,450 (159)

超声内镜联合CA242在胰腺癌诊断中的价值评估

open access: yesZhongguo shiyan zhenduanxue, 2014
胰腺癌是我国常见的肿瘤之一,发病率逐年上升,由于其位置特殊、患者临床症状隐匿,使得临床的误诊、漏诊率高。由于胰腺癌早期症状不明显,发现时多数患者已有远处转移,因此多数病人预后较差。寻找能够简便、快速、容易普及的诊断胰腺癌的方法就显得尤为重要。因此提高胰腺癌的诊断正确率是医务工作者的当务之急,近年来,超声内镜(endoscopic ultrasonography,EUS)的检查已经成为胰腺疾病诊断的首选方法[1]。糖抗原CA242是胰腺诊断的血清肿瘤标志物,在发现的众多肿瘤标志物中 ...
葛振远
doaj  

Effect of exosomes as drug carriers in chemotherapy of pancreatic cancer. [PDF]

open access: yesZhong Nan Da Xue Xue Bao Yi Xue Ban, 2023
Xu B, Zuo C.
europepmc   +1 more source

Nomogram construction based on SEER and survival prediction of pancreatic cancer patients [PDF]

open access: yes
Objective To analyze the independent factors affecting the prognosis of pancreatic cancer and construct a prediction model based on surveillance, epidemiology, and end results (SEER) database. Methods The clinical data of 7 801 American pancreatic cancer
LU Zhongxiao, TANG Jie, HUANG Wenhai
core   +1 more source

多层螺旋CT和MRI在胰腺癌诊断及术前评估中的价值研究

open access: yesZhongguo shiyan zhenduanxue, 2021
目的探究多层螺旋CT(MSCT)和磁共振成像(MRI)在胰腺癌诊断及术前评估中的价值。方法选择2016年2月至2019年12月期间成都市龙泉驿区第一人民医院收治的胰腺占位患者作为研究对象,所有患者均行MSCT及MRI扫描,以手术及病理检查结果作为金标准,分析两者诊断胰腺癌的价值及术前分期的符合度。结果 125患者胰腺癌89例,以病理检查结果作为金标准,MSCT诊断胰腺癌的敏感度、特异度、准确度、阳性预测值、阴性预测值分别为86.52%、72.22%、82.40%、88.51%、68.42 ...
秦俭, 修志刚, 何俊, 赵原
doaj  

胰腺癌细胞中Runx3基因表达及甲基化的研究

open access: yesZhongguo shiyan zhenduanxue, 2012
目的观察胰腺癌细胞中Runx3基因表达的情况,探讨其出现表达异常的机制。方法 (1)RT-PCR检测胰腺癌Panc-1、BxPC-3、AsPC-1细胞及正常胰腺组织中Runx3mRNA表达情况(2)Western blotting检测胰腺癌Panc-1、BxPC-3、AsPC-1细胞中Runx3蛋白表达情况;(3)甲基化特异性PCR(MSP)检测胰腺癌Panc-1、BxPC-3、As-PC-1细胞及正常胰腺组织中Runx3基因启动子区CpG岛的甲基化水平。结果 (1)Panc-1、BxPC-3、AsPC-
邱志东   +3 more
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The future directions of artificial intelligence in the biological benefit-dominated diagnosis and treatment of pancreatic cancer [PDF]

open access: yes
Pancreatic cancer is a high malignant tumor with insidious onset, early metastasis, and extremely poor prognosis. How to improve the early diagnosis and the prognosis of the patients is the current research focus.
QI Zhong, XING Ying, CHENG Shi
core   +1 more source

胰腺癌患者血浆中MMP-9T、IMP-1浓度变化及其意义

open access: yesZhongguo shiyan zhenduanxue, 2011
胰腺癌是发生在胰腺器官中的恶性肿瘤,5年生存率不足5%,痊愈率极低[1]。目前仍缺乏有效的实验室胰腺癌诊断指标。基质金属蛋白酶 ...
孙岩, 赵丽, 刘景
doaj  

[ZEB2 Regulates the Migration and Invasion of PANC-1 Pancreatic Cancer Cells: An Experimental Study]. [PDF]

open access: yesSichuan Da Xue Xue Bao Yi Xue Ban, 2023
Zhang RH   +7 more
europepmc   +1 more source

Progress of magnetic iron oxide nanoparticles in targeted diagnosis and treatment of pancreatic cancer [PDF]

open access: yes
Pancreatic cancer has a very poor prognosis. Early diagnosis and treatment are especially critical for improving its prognosis. Nanotechnology has been widely used in the diagnosis and treatment of pancreatic cancer. Relying on the unique physicochemical
REN Jiaqiang, WU Shuai, MO Jiantao, ZHOU Cancan, HAN Liang, WU Zheng
core   +1 more source

胰腺癌患者血浆K-ras和p53基因突变检测的研究

open access: yesZhongguo shiyan zhenduanxue, 2004
目的 检测胰腺癌患者血浆K ras和p5 3基因突变情况 ,初步分析其诊断价值。方法 本研究包括胰腺癌组 2 4例、其他疾病组 14例和健康对照组 2 1例。提取血浆DNA ,采用突变富集PCR RFLP法检测K ras基因第 12密码子突变 ,PCR SSCP 银染法检测p5 3基因第 5~ 8外显子突变。结果  2 4例胰腺癌患者中 17例血浆检测到K ras突变 ,3例检测到p5 3突变 ;2 1例健康对照者血浆中均未检测到K ras和p5 3突变 ;在 38例疑为胰腺肿瘤患者中 ,血浆K ...
奉典旭   +5 more
doaj  

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