Results 1 to 10 of about 6,073 (149)
Zhongshan Daxue xuebao. Yixue kexue ban目的探究雌性大鼠性早熟对糖代谢和脂代谢的影响。方法将60只两天龄的雌性大鼠随机分为性早熟组和正常组两组，分别在5天龄时给予达那唑（300 μg/只）或溶剂大豆油进行皮下注射，从21天龄起每天观察大鼠的阴道开口状况。建模成功的两组按照阴道开口顺序分别于阴道开口后3 d、7周龄和12周龄进行处死，处死前空腹12 h。方法测量麻醉后的体重和鼻肛长，通过酶联免疫吸附试验测量葡萄糖、胰岛素、血脂、雌二醇、瘦素和脂联素的浓度，病理切片观察肾周脂肪、子宫和卵巢的变化。结果通过正常组和早熟组两组3个时间点对比 ...
林小雅 +7 more
doaj +3 more sources
Recent Advances in the Pathogenesis of Glucolipid Metabolism Disorder in Obstructive Sleep Apnea-hypopnea Syndrome [PDF]
, 2022 Obstructive sleep apnea-hypopnea syndrome (OSAHS) is a disease marked by apnea, hypopnea, decreased oxygen saturation, and disordered sleep structure, which is a major risk for cardiovascular disease. Recent studies have found that OSAHS patients have an
WANG Yun, HE Yan, LIU Shijie, GAN Lulu, GAO Huifang, LIANG Min, ZUO Zhiheng, YANG Li
core +1 more source
Zhongguo cuzhong zazhi, 2022 目的 探讨磷脂酰肌醇3激酶/蛋白激酶B（phosphatidylinositol-3-kinase/protein kinase B，PI3K/PKB）信号通路介导脂联素对脑缺血再灌注大鼠的保护作用。 方法 随机将SD大鼠分为假手术组、模型组、脂联素治疗组和PI3K/PKB抑制剂LY294002组（抑制剂组），每组15只。通过线栓法构建大脑中动脉缺血模型，缺血1.5 h后再灌注。脂联素治疗组在再灌注2 h后，给予大鼠尾静脉注射脂联素（180 μg/100 g）；抑制剂组在再灌注2 ...
何俊芳, 刘新平, 吕学海, 王斌
doaj +1 more source
Research Progress on the Influence of Intermittent Fasting on Cardiovascular Disease Risk Factors [PDF]
, 2022 In recent years, the prevalence and mortality of cardiovascular diseases in China have shown a significant upward trend, cardiovascular disease has become a major disease endangering the health of Chinese residents.
CUI Yanru, CEN Qiuyu, WEI Juanfang, WANG Wenchun, ZHANG Anren
core +1 more source
Research progress on metabolic syndrome in related skin diseases [PDF]
, 2022 Metabolic syndrome is a set of clinical syndromes with dyslipidemia， hypertension， abdominal obesity and insulin resistance as the main manifestations， and is a risk factor for diabetes mellitus and cardiovascular diseases. In recent years， more and more
Song Mengmeng, Li Xizhi, Luo Zhicheng
core +1 more source
老年良性前列腺增生患者血浆脂联素水平及与药物疗效的关系 [PDF]
Objective: To observe the levels of plasma adiponectin and to explore the relationship between the levels of plasma adiponectin and drug efficacy in geratic patients with benign prostate hyperplasia. Methods: 70 cases of geratic men with benign prostate
Jiang, Hong-feng
core +2 more sources
Combined effects of intermittent fasting and thermogenic fat activation on the treatment and prevention of obesity in mice [PDF]
, 2023 Objective·To investigate the effects of intermittent fasting (IF) combined with thermogenic fat activation on the treatment and prevention of obesity in mice.Methods·Male C57BL/6J mice aged 8 weeks were fed by high-fat diet for 4 months and then used as ...
MA Jing, WU Kaimin, ZHAO Xuyun
core +1 more source
Zhongguo shiyan zhenduanxue, 2022 目的 探讨CT检测腹部脂肪含量在多发性骨髓瘤（multiple myeloma,MM）患者预后中的价值。方法 同时对36例新诊断MM(NDMM)患者和72例健康者腹部CT脂肪含量的检查。主要测量T12到S1的总脂肪面积（TFA）、内脏脂肪面积（VFA）和皮下脂肪面积（SFA）并进行相关分析，同时检测脂联素水平。结果 与健康人相比，NDMM患者的TFA、VFA和SFA均更高，而血浆脂联素显著降低。骨髓浆细胞百分比与SAT呈显著负相关，但与VFA/SFA呈正相关 ...
高珊 +6 more
doaj
, 2018 目的通过测定妊娠期糖尿病患者血清中瘦素、可溶性瘦素受体（soulbe leptin receptor,sLR）、脂联素、抵抗素的含量,探讨脂肪细胞因子与妊娠期糖尿病发病的相关性,初步探索瘦素对胎儿发育的影响。方法选取2014年1-12月在厦门大学附属成功医院连续产检并分娩的673例孕妇为研究对象,跟踪随访至孕晚期。根据孕2428周糖耐量试验结果,采用随机抽样选取50例血糖控制良好的妊娠糖尿病患者纳入妊娠糖尿病组,根据一般资料进行匹配选取50例糖耐量试验结果阴性者纳入正常妊娠组 ...
兰天舒, 林戎, 沈忱, 黄昭穗
core
Effects of tributyltin on Glucose Homeostasis in male mice and the recovery feasibility [PDF]
, 2016 三丁基锡(Tributyltin，TBT)是一种有机锡化合物，TBT暴露对糖尿病发生的影响报道很少。本研究以KM小鼠为对象，研究TBT长期暴露导致小鼠糖尿病发生以及停止暴露后患病小鼠的恢复。采用浓度分别为0.5、5和50μg/kg的TBT通过灌胃法对小鼠进行暴露，每3天灌胃1次，暴露持续45天后立刻恢复60天。结果显示： 1.TBT暴露45天后，小鼠体重增加，相对于对照组，50μg/kg组体重增长显著；TBT暴露小鼠的饥饿血糖水平与对照组相比有显著的升高；并出现葡萄糖不耐受。停止TBT暴露恢复60天后 ...
李炳水
core