Results 11 to 20 of about 377,353 (146)

PI3K/AKT信号通路介导脂联素对脑缺血再灌注大鼠的保护作用 The Protective Effect of Adiponectin on Rats with Cerebral Ischemia-reperfusion through PI3K/PKB Signaling Pathway

open access: yesZhongguo cuzhong zazhi, 2022
目的 探讨磷脂酰肌醇3激酶/蛋白激酶B(phosphatidylinositol-3-kinase/protein kinase B,PI3K/PKB)信号通路介导脂联素对脑缺血再灌注大鼠的保护作用。 方法 随机将SD大鼠分为假手术组、模型组、脂联素治疗组和PI3K/PKB抑制剂LY294002组(抑制剂组),每组15只。通过线栓法构建大脑中动脉缺血模型,缺血1.5 h后再灌注。脂联素治疗组在再灌注2 h后,给予大鼠尾静脉注射脂联素(180 μg/100 g);抑制剂组在再灌注2 ...
何俊芳, 刘新平, 吕学海, 王斌
doaj   +1 more source

MMC celebrating 6 years of experience and expansion 庆祝MMC六年的经验和壮大

open access: yes, 2022
Journal of Diabetes, Volume 14, Issue 5, Page 356-357, May 2022.
Itamar Raz
wiley   +1 more source

老年良性前列腺增生患者血浆脂联素水平及与药物疗效的关系 [PDF]

open access: yes, 2014
Objective: To observe the levels of plasma adiponectin and to explore the relationship between the  levels of plasma adiponectin and drug efficacy in geratic patients with benign prostate hyperplasia. Methods: 70 cases of geratic men with benign prostate
Jiang, Hong-feng; Department of Gerontology , Affiliated Puai Hospital of Tongji Medical College,Huazhong University of Science and Technology, Wuhan, Hubei, China
core   +1 more source

合成应用于木质纤维素水解液精制的吸附树脂

open access: yes, 2016
对稀酸水解液进行精制脱毒是生化法中高效利用木质纤维素类生物质不可缺少的处理过程.本文以三种混合木质纤维素类生物质水解液为研究对象,以苯乙烯等为原料合成吸附树脂,考察了二乙烯基苯(DVB)浓度、单体和交联剂比例、非极性和弱极性单体等条件对吸附树脂吸附效果的影响.研究发现,固液比1.4∶40 的情况下,不经过任何其他工艺,仅用吸附树脂,糠醛的去除率可以达到76%以上,5一羟甲基糠醛去除率可超过40%,可溶性木质素的最高去除率约为87%,而总糖损失率在8%左右.一定范围内提高交联剂的量可提高树脂的吸附性能 ...
黄超   +5 more
core   +4 more sources

Optimization of Induction Condition of 3T3-L1 Preadipocytes Differentiation(前体脂肪细胞3T3-L1诱导分化条件的优化) [PDF]

open access: yesShipin kexue jishu xuebao, 2014
The present study investigated the influences of the concentration of 3-isobutyl-1-methylxanthine (IBMX), dexamethasone and insulin during the combined induction stage (first stage) and the corresponding induction time, the induction time and ...
WANG Yousheng(王友升)   +2 more
doaj   +1 more source

桉木木质素提取及环氧树脂的合成表征

open access: yes, 2019
利用木质素大分子与双酚A相似性,采用木质素替代双酚A制备环氧树脂可减少化石原料双酚A的使用。采用衣康酸助催化高温液态水耦合酶催化水解法提取人工林剩余物―桉木的木质素。电子扫描电镜SEM检测表明:木质素分子量颗粒分布均一,木质素含量97.6%,酚羟基含量1.48 mmol/g。利用木质素与双酚A结构相似,在碱催化下与环氧氯丙烷反应合成木质素基环氧树脂。傅立叶红外光谱检测表明,氢氧化钠催化下发生了化学反应,生成了环氧基,环氧值为0.36 mol/100g。热失重TGA分析显示:双酚A环氧树脂失重发生在314.
苗长林   +4 more
core   +4 more sources

Renoprotective effects of brown adipose tissue activation in diabetic mice 棕色脂肪激活对糖尿病小鼠的肾脏保护作用

open access: yesJournal of Diabetes, Volume 11, Issue 12, Page 958-970, December 2019., 2019
Highlights This study demonstrates that of brown adipose tissue (BAT) with CL316,243 attenuates the progress of diabetic kidney disease (DKD). Mechanistically, the activation of BAT improved concentrations of circulating adipokines and microRNAs, which further affected the diabetic kidney and reactivated the AMP‐activated protein kinase/sirtuin 1 ...
Ying‐Ying Cai   +10 more
wiley   +1 more source

International clinical practice recommendations on the definition, diagnosis, assessment, intervention, and psychosocial aspects of developmental coordination disorder – Chinese (Mandarin) translation

open access: yesDevelopmental Medicine &Child Neurology, Volume 61, Issue 3, Page E1-E35, March 2019., 2019
目的 本国际临床指南由欧洲残疾儿童学会(the European Academy of Childhood Disability,EACD)牵头制定,旨在解决发育性协调障碍(developmental coordination disorder,DCD)的定义、诊断、评估、干预以及与社会心理方面的临床应用关键问题。 方法 本指南针对五个领域的关键问题,通过文献综述和专家团队的正式讨论达成共识。为保证指南的循证基础,以“机制”、“评估”和“干预”为检索词, 对2012年更新以来提出的最新建议以及新增的“社会心理问题”和“青少年/成人”为检索词进行检索。根据牛津大学循证医学中心证据等级 (证据水平 [level of evidence, LOE]1–4) 将结果进行分类,最终转化为指南建议。并由国际 ...
Jing Hua   +6 more
wiley   +1 more source

腹部脂肪CT检测在新诊断多发性骨髓瘤中的预后价值分析

open access: yesZhongguo shiyan zhenduanxue, 2022
目的 探讨CT检测腹部脂肪含量在多发性骨髓瘤(multiple myeloma,MM)患者预后中的价值。方法 同时对36例新诊断MM(NDMM)患者和72例健康者腹部CT脂肪含量的检查。主要测量T12到S1的总脂肪面积(TFA)、内脏脂肪面积(VFA)和皮下脂肪面积(SFA)并进行相关分析,同时检测脂联素水平。结果 与健康人相比,NDMM患者的TFA、VFA和SFA均更高,而血浆脂联素显著降低。骨髓浆细胞百分比与SAT呈显著负相关,但与VFA/SFA呈正相关 ...
高珊   +6 more
doaj  

脂联素在脂肪组织切口愈合中的作用及机制研究

open access: yesZhongguo shiyan zhenduanxue, 2013
目的观察脂联素在脂肪组织切口愈合(ATWH)中的作用,探讨脂联素在ATWH中的作用机制。方法制作猪ATWH模型;随机分为脂联素干预组和对照组(各组n=5),观察ATWH等级,分析脂联素对ATWH的影响。应用免疫荧光标记技术和电镜观察脂肪细胞凋亡变化情况,分析脂联素水平对脂肪细胞凋亡的影响。结果干预组切口愈合等级显著优于对照组 ...
濮勇, 陶曙, 姜洋, 肖亮
doaj  

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