Results 11 to 20 of about 5,866 (154)
Journal of Diabetes, Volume 15, Issue 9, Page 714-723, September 2023., 2023 Highlights There was a U‐shaped relationship between glycemic gap and stroke recurrence during a long‐term follow‐up in a Chinese ischemic stroke registry. Clinical physicians should remain vigilant in the fluctuation of glucose level and use individualized glucose control strategies in patients with ischemic stroke.
Kang Yuan +10 more
wiley +1 more source
Journal of Diabetes, Volume 15, Issue 4, Page 289-298, April 2023., 2023 Highlights This long‐term longitudinal study demonstrates the association between alcohol consumption and health outcomes in patients with abnormal glucose metabolism including type 2 diabetes mellitus and prediabetes. Occasional drinking (less than once a week) reduces the risk of all‐cause mortality, while heavy alcohol consumption (≥30 g/day for men
Mengzhao Cui +7 more
wiley +1 more source
Journal of Diabetes, Volume 14, Issue 8, Page 495-513, August 2022., 2022 Highlights During the past 30 years, globally, the disease burden of stroke burden has decreased substantially; however, the disease burden of stroke attributable to high fasting plasma glucose (HFPG) failed to achieve a significant decline. The population‐attributable fraction of HFPG for stroke burden has been increasing across different regions ...
Yang Liu +8 more
wiley +1 more source
The Anatomical Record, Volume 304, Issue 11, Page 2538-2551, November 2021., 2021 Abstract This study aimed to explore the changes in functional connections between cerebral hemispheres and local brain regions functional activities in patients with acute ischemic stroke (AIS) treated with International Standard Scalp Acupuncture (ISSA).
Huacong Liu +11 more
wiley +1 more source
Journal of Advanced Nursing, Volume 77, Issue 3, Page 1546-1555, March 2021., 2021 Abstract Aims Determine sex‐ and age‐associated psychophysical and neurophysiological differences in the processing of pain across the adult lifespan. Design Preliminary, exploratory, cross‐sectional study. Methods Using psychophysics (to measure intensity and unpleasantness) and functional magnetic resonance imaging blood oxygenation level dependent ...
Sebastian W. Atalla +8 more
wiley +1 more source
Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 6, Page 749-760, June 2025.ABSTRACT Objective Placental dysfunction can result in small‐for‐gestational age (SGA) or fetal growth restriction (FGR). The aim of this prospective cohort study was to assess the association of the cerebroplacental ratio (CPR) and other more conventional fetoplacental Doppler indices, circulating placental growth factor (PlGF) levels and soluble fms ...
J. Hong +6 more
wiley +1 more source
Brain and Behavior, Volume 15, Issue 4, April 2025.cTMS can effectively improve the motor function of patients with stroke, with significant efficacy in balance and limb motor function. The therapeutic effect of cTMS was more pronounced when intervening in the subacute phase, and when the excitatory stimulation mode and moderate intensity (≤ 80% RMT) were used.
Yongxin Zhu +7 more
wiley +1 more source
Effect of oleoylethanolamide on the recovery of motor function during the chronic phase after cerebral ischemia in mice and its mechanism [PDF]
, 2017 研究背景：缺血性脑卒中是致残率最高的疾病，患者长期伴有躯体感觉运动功能障碍等脑缺血慢性损伤，给患者及家庭带来极大的痛苦和沉重的负担。目前临床上，对于脑缺血慢性损伤尚无有效的治疗药物，因此，研究和寻找改善脑缺血慢性损伤的药物具有十分重要的意义。研究发现脑缺血损伤慢性期，脑损伤周边区过度激活的星形胶质细胞合成和释放细胞外基质如Neurocan等，可抑制轴突再生，阻碍神经功能恢复。过氧化物酶体增殖物激活受体α(peroxisomeproliferator-activatedreceptor，PPARα ...
张亚莉
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基于生物信息学途径筛选缺血性脑卒中关键基因及药物预测 [PDF]
, 2021 目的筛选缺血性脑卒中的关键基因及重要信号通路，预测可能对脑卒中有用的药物。方法从GEO数据库下载GSE98319基因芯片数据，该数据包含了假手术组、大脑中动脉梗塞组（MCAO）小鼠的基因芯片检测结果。用R语言的Limma包对数据进行差异表达分析，P<0.05且|log2FC|>0.6的基因为差异表达基因。借助STRING网站构建差异表达基因的蛋白质相互作用网络（PPIN）后由Cytoscape软件进行核心子网络筛选及可视化输出。筛选出核心基因后用实时荧光定量PCR（qRT- PCR ...
于瑜, 王钟兴
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, 2010 目的观察前胡甲素(Pd-Ia)对小鼠局灶性脑缺血损伤的保护作用及特点。方法线栓法制备小鼠大脑中动脉栓塞脑缺血损伤模型。Pd-Ia(1,5,10mg/kg)在缺血前0.5h腹腔给药1次;或在缺血前1,0.5h、缺血同时、再灌注同时、再灌后0.5h及再灌后1h各腹腔给予Pd-Ia5mg/kg。脑缺血1.5h,再灌注24h后,测定小鼠神经功能缺失评分、脑梗死体积、脑水肿等评定脑缺血损伤的指标;测定血清中丙二醛(MDA)和超氧化物岐化酶(SOD)的活性。结果Pd-Ia(5,10mg/kg)缺血前0 ...
周宇 +5 more
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